J.C. Romero, the Philadelphia Phillies star who was suspended for steroid abuse last August, has taken legal action against the makers and distributors of nutritional supplements. The star pitcher alleged that they are responsible for his positive test.

Romero filed a 27-page lawsuit on Monday in New Jersey Superior Court in Camden County. In the lawsuit, he blamed the product 6-OXO Extreme for traces of androstenedione found in his urine on Aug. 26, 2008. The lawsuit also includes various other counts, including negligence, intentional misrepresentation and consumer fraud.

GNC, Vitamin Shoppe, Ergopharm and Proviant Technologies are the four defendants named under the lawsuit. Among these, the latter two companies are owned and operated by Patrick Arnold, an Illinois-based chemist who is in federal prison for having role in the BALCO affair. When asked about the lawsuit, Arnold did not give any statement.

Romero said, “I purchased an over-the-counter supplement that I was told and believed would not cause me to test positive.” “These events have hurt me deeply and placed a cloud over my career, accomplishments and family. It is my hope that I can finally start to put this event behind me and protect the interests of others who rely on manufacturers and retailers to be honest about their products.”

From New York Daily News:

Suspended Phillies reliever J.C. Romero is suing the makers and distributors of nutritional supplements that he says are responsible for his positive steroid test last August.

The 27-page lawsuit, filed Monday in New Jersey Superior Court in Camden County, blames the product 6-OXO Extreme for traces of androstenedione found in the pitcher’s urine on Aug. 26, 2008.

The numerous counts in the lawsuit include negligence, intentional misrepresentation and consumer fraud. The four defendants named are GNC, Vitamin Shoppe, Ergopharm and Proviant Technologies.

The star Phillies pitcher was tested positive for androstenedione on Aug. 26, 2008 and received a 50-game suspension order, which was not made public until January of this year. MLB announced his ban later in January. Despite of his suspension, Romero was allowed to work out with the Phillies in spring training session and in pregame practices without being paid.

Gary Wadler, a New York internist affiliated with the World Anti-Doping Agency stated that Romero situation had highlighted a well-known problem with the under-regulated supplement industry.

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A journalist of The New Yorker, Margaret Talbot made an observation and study on the lifestyle among high school and undergraduate students. In her observation, she said that a lot of the youngsters are not aware that they are actually taking brain steroids or commonly referred as neuro enhancers. According to her, most high school and undergraduate students, take these kinds of drugs in order to cope with all the school works and social life. She stated that students face a lot of pressure because they need to accomplish school requirements, attend to their works and prepare for graduate studies. Thereby, these youngsters do whatever it takes to sustain the physical and psychological demands.

From The Collegian Online:

In this week’s issue of The New Yorker, journalist Margaret Talbot investigated the world of high-school and undergraduate students who are healthy, but take what she calls “neuro-enhancers,” drugs commonly prescribed for A.D.D. such as Ritalin. With these, students seek an edge to grind out long hours to produce quality class work. However, she finds that often times students take these not to be at the top of the class but to basically do everything needed to be considered a well-rounded student. Due to pressures for students to do a lot in little time and to succeed, students will continue to rely on these drugs, and it could only increase in the future.

Talbot also added that neuro-enhancers such as Ritalin are usually given to A.D.D patients. This practice allows students to stay awake until late in the evening in order to produce quality paper works and finish tons of school requirements. She said that these pressures given to the students may be dangerous to them in the future, since they will continue relying on these types of brain stimulants or enhancers.

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In Blissfield Michigan, Travis Babbitt was awarded first place for his public service announcement about steroids and sports. The audio and video production that he presented in Lenawee Intermediate School District Tech Center was entered in a completion through the help of Michigan Association of Broadcasters Foundation. The media production was a result of the 30-to 60-second commercial assignment given to students.

He did a 30-second video containing some footage of his classmates lifting weights. He also included the facts on how steroids can affect people who use them.

Travis Babbitt said that he, himself is involved in sports. He is the defensive lineman for the football team of the Blissfield High School. He also added that his inspiration came from the on going issue in Major League Baseball.

From The Daily Telegram:

A Blissfield teen received a first-place award for his public service announcement about steroids and sports.

The assignment led to him taking home an award certificate on March 11 at a banquet in Grand Rapids. There he received first-place recognition in the television Michigan High School Athletic Association Sports PSA category by the Michigan Association of Broadcasters Foundation.

“With everything going on in Major League Baseball with steroids, I thought it would be fitting to do that (topic),” he said.

According, Melissa Conklin, Travis’ teacher on audio and video production, that she really insisted every student to join the contest. She also added that the competition will give students, especially if they win, the opportunity to talk with professional broadcasters when they win and attend the award conference.

Travis Babbitt said that he was excited upon knowing that he won the competition. He added that he had pulled out his phone and started sending text messages to his parents and friends. Babbitt will come back and pursue his independent study next year.

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Big Brown, winner of last year’s Kentucky Derby, became popular not just by winning first in the race but also because of steroid issue. Recently, Rick Dutrow Jr., told the media that he did give Big Brown Winstrol every 15th of the month.

Winstrol used to be legal in Kentcucky Derby, but due to the outburst brought by the incident, the use of anabolic steroids was banned. No horse will be allowed to join in the race in Triple Crown series with the 135th running of the Kentucky Derby.

From Daily News:

The steroid ban went into effect on Jan. 1 in almost every racing jurisdiction and had already been adopted by California for last year’s Breeders’ Cup at Santa Anita in October.

In October, the National Thoroughbred Racing Association created the Safety and Integrity Alliance, calling for reforms that include the adoption of uniform medication rules and penalties, the ban of steroids, out-of-competition testing for blood and gene doping agents, pre- and post-race veterinary examinations, mandatory on-track injury reporting, enhanced backstretch security and having each track support and maintain an association with qualified retraining and adoption programs for thoroughbreds no longer competing.

The issues on Big Brown and the death of Eight Belles brought awareness on some unfair practices and procedures done on horses. Aside from steroid ban, other changes were made including the banning of toe grabs placed under the horses’ shoes while racing or training. However, investigations on the cause of death of the Belles revealed that no steroid residues were found in the bodies.

Three trainers, Larry Jones, Rick Dutrow Jr. and Michael Matz agreed on the changes done because they all want is the best for their horses. They believe that there should have national body to employ rules on everything on the sport including licensing and medication.

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The story on steroids of Cardinals’ Troy Glaus as reported by The New York Times last Sunday has made John Moozeliak to comment on the report. He said that he has known Troy for years and he believes that his player will not repeat the same decision he did before. John added that Glaus is working hard to recover and aims to return to the game as soon as possible.

From MLB.com:

“I think he’s very well aware of the decisions he’s made in the past and he is not going to duplicate that again,” Mozeliak said after meeting with Glaus in Phoenix, according to a report in the St. Louis Post-Dispatch.

“I made it very clear that this is something that was in the past and Major League Baseball has dealt with it, and that the Cardinals organization acknowledges that and don’t expect it to come up again,” Mozeliak said. “We understand moving forward that he is committed to this program and getting back to St. Louis as quickly as possible.”

According to the report of The New York Times, Troy Glaus admitted that he told the investigating officials in 2005 that he did use performance-enhancing drugs or steroids in 2003 and 2004. But Troy confirmed that the decision he made was to help him recover from a shoulder injury.

Glaus said that, in 2003, he and the other players were allegedly prescribed by a certain doctor from California to use steroid to repair his torn labrum and rotator cuff in his right shoulder. However, Troy did not make any comment on the specifics of the report made by The Times.

Cardinals’ general manager, John Mozeliak that Troy is doing well on his rehab program and is completely determined to get back to the team. Troy is now rehabbing with a private trainer in Phoenix.

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John Mozeliak, the general of St. Louis Cardinals, has recently spoken to the media regarding the admission of Troy Glaus that he used steroids in 2003 and 2004. According to the statement of Glaus he used that steroid to help him heal his injured shoulder. In 2005, Glaus told the investigating officials that a doctor from California allegedly did prescribe him and the other players of steroids in order to repair a torn labrum and rotator cuff in his right shoulder.

The Cardinals Manager told the press that he had known Glaus for years and he trust him to work as hard on the rehab as his will to get back on the team.

From MLB.com:

Cardinals general manager John Mozeliak met with Troy Glaus on Monday to discuss a newspaper report that said the third baseman told authorities that he used steroids in 2003 and 2004 to help him recover from shoulder injuries.

“I think he’s very well aware of the decisions he’s made in the past and he is not going to duplicate that again,” Mozeliak said after meeting with Glaus in Phoenix, according to a report in the St. Louis Post-Dispatch.

“At this point, there is no reason [to go over the past]. I’m not going to comment,” Glaus said. “I’m in there [the gym]. I’m doing my exercises, and I’m going to do everything I can to get back as soon as I possibly can. From the exercises I’m doing now or working out — whatever it is I have to do so that when I come back, I’m ready to play.”

Mozeliak believes that Troy Glaus will not do the same mistake again. He also stated that Glaus is serious in getting back on the game as quickly as possible. Troy Glaus is having his rehab with a private trainer in Phoenix.

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A report says, Marijuana, one of the most commonly abused drugs among high school and college students, is tied with a severe form of vomiting syndrome and compulsive bathing behavior. The syndrome is increasingly recognized with extensive marijuana abuse.

Though, this clinical manifestation of severe vomiting sickness linked with chronic abuse of marijuana is doubtful, but was acknowledged by Dr. Sontineni and his colleagues at the Creighton University of Omaha, NE.

Recent findings done to the neurobiology of cannabis led to the recognition of different types of receptors, including forms that mediate neuropsychiatric and immunologic effects.

According to Dr. Sontineni, identification of the syndrome leads to delayed diagnosis and expensive diagnostic investigations. Increased use of marijuana, on a continous basis for several years, by the population of USA, especially among youths, would see a sharp rise in the number of diagnosed cases every year.

The syndrome was first recognized in Australia around the Adelaide hills and from there onwards, scientists and doctors at several institutions across the world are engaged in identifying more cases with this new vomiting syndrome due to chronic marijuana abuse.

From Science Daily:

Marijuana, a commonly abused drug among high school and college students, is linked to a severe form of vomiting syndrome and compulsive bathing behavior. This form of severe vomiting sickness is increasingly recognized with widespread abuse of marijuana. The syndrome usually subsides with strict abstinence from marijuana abuse.

This obscure clinical manifestation of severe vomiting sickness due to chronic abuse of marijuana was recognized by Dr. Sontineni and his colleagues at the Creighton University of Omaha, NE.

Recent research into the neurobiology of cannabis has led to the identification of different receptor types including two specific types that mediate neuropsychiatric and immunologic effects.

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It is a rare case to have steroids busts in East Providence; this is according to Sgt. Diego Mello, East Providence Police. But on April 2, the East Providence arrested Paul Thomas Reis for possessing more than $2,500 worth of steroids.

Prior to the arrest, police said that they had Reis under surveillance after an informant tipped them about Reis selling anabolic steroids and marijuana. Evening of April 2, while the police is observing the actions of Reis, they noticed that he stopped for a while at a certain address in Edward Avenue when he left the area; he was asked to pull over due to a vehicle violation. Reis admitted that he was on his way home to smoke marijuana, so the officers asked his consent to search his residence.

From East Bay RI.com:

On April 2, however, police arrested Paul Thomas Reis, 31, of 175 Hatton St. with more than $2,500 worth of steroids. According to police reports on the incident, the vice unit had been monitoring Mr. Reis after receiving information from confidential informants that he had been selling anabolic steroids and marijuana.

Mr. Reis was charged with two counts of manufacturing, possessing or delivering a schedule III, IV substance, possession of arms by a convict and possession of marijuana first offense.

During the search, police found a briefcase containing multiple brands of steroid compounds - 80 Tamoxifen 10 milligram tablets, 33 ampules of 250 milligram Testosterone Enanthate, 257 Methandienone tables, 358 Stanozolol tables, five bottles of Nandrolone Deca, one bottle of Boldenone, one bottle of Sustanon, and one bottle of Andropen 275. Additionally, they found five receipts from the Medfast Compounding Pharmacy, Pittsburgh, Penn., 25 3ml/22ga syringes and a .22 caliber Davis Industries Derringer handgun, which was reported missing in 2003 at the Plymouth County, Connecticut.

Reis is facing multiples charges on illegal possession of steroids and marijuana, and another count on possession of a firearm.

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Steroid dependency caused several psychiatric disorders; this is what the new study has revealed. According to Professor Harrison G. Pope of Harvard Medical School, disorders relating to conduct and image are linked to steroid addiction or dependency. These results were achieved after interviewing and examining the medical histories of 134 weight lifters, which were grouped into three – non-steroid users, steroid users that has no dependency and steroid users that had developed addiction..

Body image and conduct disorders are respectively the juvenile versions of anti-social disorder and obsession to body size and appearance. Pope said that even steroid dependency is a new scenario in drug abuse; researches should totally reveal the disadvantages of using steroids. He added that science has just started finding answers to the long-term hazards of steroids.

From Harvard Crimson:

A new study has found that people with conduct disorder, body image disorder, or both are more prone to become dependent on anabolic steroids, according to Harrison G. Pope ’69, a Harvard Medical School professor of psychiatry and lead author of the study.

“Doctors know a lot about alcohol problems and addiction to profitable street drugs, but they know little about anabolic steroids, they’re poorly understood,” he said. “This is an area where [the scientific community] needs to be educated as this problem comes over the horizon.”

According to Pope, there are some wrong notions about steroids, particularly the belief on developing prostate cancer. He said that steroid users are not prone to develop this type cancer but rather increase the chance of having cardiac diseases and mood disorder. He stated that some effects maybe reversible once steroid is stopped.

There are no conclusions yet on this study, but Pope believes that having more researches on this issue is the essential in order to dig deeper on the continuous issue of steroids.

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A new drug compound has been identified by the researchers at the University of Southern California and according to them the drug appears to target tumor cells and surrounding blood vessels without showing any negative side effect usually associated with Cox-2 inhibitors.

As per the data presented at the AACR 100th Annual Meeting 2009, the compound named 2.5-dimethyl-celecoxib (DMC) would have a strong anti-tumor effect even while attacking the vasculature that provides the blood supply necessary for tumor growth.

Florence M. Hofman, professor of pathology at the Keck School of Medicine of USC, said “If left behind, the blood vessels within the tumor will help the tumor cells to survive and re-grow.” He further added that they believed that DMC might prove useful in the treatment of brain tumors, such as gliomas, which are highly vascular and also appeared to be a promising long-term treatment as it did not have the negative cardiovascular effects typically associated with Cox-2 inhibitors.

Hofman explained that Cox-2 inhibitors are most commonly used as anti-inflammatory drugs and have been effective in treating certain kinds of cancer. However, its long-term use can cause increased risk of heart attack and stroke while DMS mainatins its anti-tumor activity without inhibiting action of Cox-2.

From Science Daily:

Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors.

The compound 2.5-dimethyl-celecoxib (DMC) appears to have a strong anti-tumor effect while also attacking the vasculature that provides the blood supply necessary for tumor growth, according to data presented at the AACR 100th Annual Meeting 2009. The findings were presented on April 19.

“If left behind, the blood vessels within the tumor will help the tumor cells to survive and re-grow,” says Florence M. Hofman, Ph.D., professor of pathology at the Keck School of Medicine of USC. “We believe that DMC will be particularly useful for treating brain tumors such as gliomas, which are highly vascular.

The study focused on testing the effectiveness of the DMC compound by isolating endothelial cells, which lines the interior surface of blood vessels, from human nonmalignant brain and glioma tissues and treating them with DMC.

In the study, the researchers found that the drug was not only cytotoxic to tumor-associated endothelial cells, but also suppressed cell proliferation process and migration occurrence without having toxic effects on normal tissues.

Hofman concluded with the saying that though their research focused mainly on brain tumors, but they believed that the drug might work for several different tumors that are dependent on blood vessels. However, further research would help them in understanding its full potential.

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