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Archive for  January 2010

Thursday 28, Jan 2010

Lung function halted by Vitamin D in COPD and Asthma

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Lung function halted by Vitamin D in COPD and Asthma

According to researchers at the University of Pennsylvania, Vitamin D can slow down the progressive decline in the ability to breathe occurring in asthmatic patients as a result of human airway smooth muscle (HASM) proliferation.

Gautam Damera, Ph.D., presented the research at the American Thoracic Society’s 105th International Conference in San Diego on May 20, and said that Calcitriol is effective when it comes to offering anti-inflammatory effects.

It was found by the group that a form of vitamin D synthesized within the body, calcitriol, has the ability to reduce growth-factor-induced HASM proliferation in cells isolated from both persons with asthma and from persons without the complication.

Thursday 28, Jan 2010

Anti-asthmatic and anti-inflammatory drugs without side effects

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Black asthmatic teens more likely to be resistant to steroids than their white counterpartsCorticosteroids are considered to be powerful drugs when it comes to treating inflammatory conditions such as asthma and other chronic diseases. Though they provide relief to the patients, they cannot be completely termed as free from side effects.

In an attempt to develop drugs free from side effects, a research team spearheaded by Dr. Henry J. Lee had been developing “antedrugs” at Florida A&M’s College of Pharmacy.

In the study titled Anti-Inflammatory Activities of New Steroidal Antedrugs Isoxazoline Derivatives that was conducted by Drs. Henry J. Lee, Younes J. Errahali, LeeShawn D. Thomas, Brenda G. Arnold and Glory B. Brown, all of the Florida Agricultural and Mechanical University, College of Pharmacy and Pharmaceutical Sciences, Tallahassee, Florida, the effectiveness of Antedrug was examined.

The project research was supported by the National Institutes of Health.

Wednesday 27, Jan 2010

Asthma management simplified by combo inhaler

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Asthma management simplified by combo inhalerAccording to a recently concluded review, patients suffering from may have a new treatment option allowing them to effectively manage their condition with a single prescribed inhaler that contains two medicines.

It is important to note that asthma patients presently make use of maintenance or preventive medication on a regular basis for controlling symptoms and improving lung function.

This review appeared in an issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates research in all aspects of health care.

Carlos Camargo, M.D., an associate professor of medicine at Harvard Medical School and specializing in asthma and chronic obstructive pulmonary disease, said that this single inhaler therapy is a new and interesting approach to chronic asthma treatment.

Wednesday 27, Jan 2010

Brain tumor progression in recurrent disease can be delayed by Avastin

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Brain tumor progression in recurrent disease can be delayed by AvastinAccording to a retrospective study of 22 patients conducted by a researcher at the Seattle Cancer Care Alliance, the use of Avastin alone can prove to be an effective treatment option when it comes to curing a subgroup of recurrent Grade 3 brain tumors in terms of delaying tumor progression.

Avastin, known generically as bevacizumab, is the first-ever approved therapy that has been designed for inhibiting angiogenesis that is a process by which new blood vessels develop and transport important nutrients to a tumor.

Marc Chamberlain, M.D., author of the study published in the April 15 edition of the journal Cancer and director of the Neuro-oncology Program at the SCCA and a professor of neurology and neurological surgery at the University Of Washington School Of Medicine, said that bevacizumab has the unique potential of being the best palliative treatment.

Wednesday 27, Jan 2010

Teriparatide better than Alendronate for treating steroid-induced Osteoporosis

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osteoporosisGlucocorticoid-induced osteoporosis (OP) is now treatable with Teriparatide, which is a synthetic form of the human parathyroid hormone, according to a recent study.

It was found by the researchers that patients with glucocorticoid-induced osteoporosis and treated with teriparatide for a period of 36 months had a significant increase in BMD (bone mineral density) and fewer new vertebral fractures than those treated with alendronate.

The findings of this study were published in the November issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR).

Wednesday 27, Jan 2010

Athletes on performance enhancers more likely to abuse alcohol and substance drugs

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athleteCollege athletes who make use of performance enhancing substances can be at an increased risk of abusing alcohol and indulging in substance abuse, as per a new research in the Journal of Studies on Alcohol and Drugs.

In a study involving 234 male athletes, it was found that athletes using performance enhancers such as steroids and weight-loss supplements are more likely to use drugs like marijuana and cocaine.

Study co-author Dr. Robert J. Pandina, director of the Center of Alcohol Studies at Rutgers University in Piscataway, New Jersey, said that the concerning implication is that many athletes are not only using recreational drugs but also suffering from harmful effects.

Tuesday 26, Jan 2010

Children open for herbal product experimentation may try illicit drugs

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Children open for herbal product experimentation may try illicit drugsAccording to a recent study, adolescents who have tried herbal products are six times more likely to try illicit drugs such as cocaine and as much as fifteen times more likely to use anabolic steroids when compared to children who have never tried herbal products.

Susan Yussman, M.D., M.P.H., assistant professor of pediatrics in the Division of Adolescent Medicine at the university’s Golisano Children’s Hospital at Strong and study author, remarked that children expressing a desire to experiment with herbal products are more likely to try illicit drugs.

The cross-sectional study may prompt the need for further studies to determine which all herbal products can be associated with use of which certain drugs.

Tuesday 26, Jan 2010

Body Image: Cause of concern among boys and girls

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Body Image: Cause of concern among boys and girlsA nationwide survey of more than 10,000 adolescents that appeared in an issue of Child Health News has reported that body image is a concern among both boys and girls. It was noted that this image may prompt them to use hormones and dietary supplements to improve their physique.

The survey also reported that the adolescent supplement users appear to be deeply influenced by the media.

It was noted that some of the most popular products for improving body image were creatine, amino acids, the amino-acid metabolite HMB, the hormone dehydroepiandrosterone (DHEA), growth hormone, and anabolic steroids.

Dr. Alison Field, an epidemiologist in the Division of Adolescent Medicine and the Department of Psychiatry at Children’s Hospital Boston and the study’s first author, said that protein powders may be relatively safe but steroids have known side effects.

Tuesday 26, Jan 2010

Anti-inflammatory steroid use can increase risk of death

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Anti-inflammatory steroid use can increase risk of deathAccording to a new review of studies about the use of anti-inflammatory steroids for traumatic head injuries such as car crashes, the risk of death is increased due to such usage.

This analysis that was published by the British-based Cochrane Library draws heavily from a study of corticosteroid treatment for brain injury involving more than 10,000 patients.

Dr. Phil Alderson, lead author of the Cochrane study, said that the considerable increase in death with steroids found participating in the trial suggests that steroids are no longer to be routinely used in patients with traumatic head injury.

This review appeared in the January issue of The Cochrane Library, a publication of the Cochrane Collaboration that evaluates medical research.

Tuesday 26, Jan 2010

Long-term aggression triggered by steroids in teens

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Long-term aggression triggered by steroids in teensSteroids can have a long-lasting effect on brains of teenagers and may even flip the brain switch of adolescents for aggression that may last as much as two years, as per a U.S. study.

It was suggested by the study researchers that anabolic steroids may result in brain changes on a permanent basis, a fact that was based on results noticed in hamsters.

In the recent past, neuroscientists have shown a great concern about the rising adolescent abuse of anabolic-androgenic steroids (AASs).

This study appeared in the current edition of Behavioral Neuroscience, Vol. 120, No. 1.

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