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Archive for  March 2010

Wednesday 31, Mar 2010

Pharmaceutical agents emerging as sports doping products

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Pharmaceutical agents emerging as sports doping productsThe black market is full of non-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) that are used for their performance enhancing qualities, according to researchers from the German Sport University Cologne in Germany.

The detection of Andarine, a drug candidate, in a product sold via the Internet was recently demonstrated for the first time suggesting easy availability of authentic SARMs.

The issue of pharmaceutical agents emerging as sports doping products was recently addressed at the Conference of Parties to the International Convention against Doping in Sport, held October 26-28, 2009 at the United Nations Educational, Scientific and Cultural Organization’s (UNESCO) headquarters in Paris.

Wednesday 31, Mar 2010

New mechanism identified for setting apart males and females

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New mechanism identified for setting apart males and females  A new mechanism has been identified by Walter Wahli and colleagues, at the University of Lausanne, Switzerland underlying the differential expression of proteins in male and female mice.

Expression of liver proteins controls a varying number of whole-body processes like energy generation, and lipid and steroid hormone production and turnover.

The research appeared in September 1, 2009 issue of the Journal of Clinical Investigation.

It was suggested by the authors that PPAR-alpha agonists might provide a new approach to prevent estrogen-induced intrahepatic cholestasis, the most common liver disease during pregnancy.

Wednesday 31, Mar 2010

Asthma control in Preschoolers

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Asthma control in PreschoolersAccording to a review in CMAJ (Canadian Medical Association Journal), asthma is the commonest of all chronic diseases in children besides being a prime reason for hospital admissions yet there is lack of asthma control in 26 to 45 percent of children.

The review offered key insights to differentiate between transient asthma and chronic asthma in preschoolers and information on managing both types.

More research is required to examine the effectiveness of treatments in young children, as per the study authors.

Wednesday 31, Mar 2010

Alarming trends noticed among steroid users

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Alarming trends noticed among steroid usersA new survey of 500 steroid users has revealed that most of the users belong to the non-athlete category and their purpose of using steroids is to improve their physical appearance. It was also revealed that steroid users are administering themselves with larger doses than previously recorded and health concerns related to use of steroids are not enough to deter their steroid use.

The survey results were released at the 52nd American College of Sports Medicine (ACSM) Annual Meeting in Nashville, Tennessee.

This survey was conducted with an aim to ascertain the present-day trends among steroid users.

Tuesday 30, Mar 2010

Natural hormone can guard muscle from atrophy

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Natural hormone can guard muscle from atrophyA new treatment option was recently found by researchers to treat the common problem of muscle atrophy, as per results of an animal study that were presented at The Endocrine Society’s 91st Annual Meeting in Washington, D.C.

Some of the presently recommended options for treating muscle atrophy are anabolic steroids (testosterone) and insulin-like growth factor 1 (IFG-1) but there have been some concerns about their usage due to safety and effectiveness, as per study co-author Andrea Graziani, PhD. and molecular biologist with the Department of Clinical and Experimental Medicine and the Biotechnology Center for Applied Medical Research, University of Piemonte Orientale, Novara, Italy.

The review was supported by Italian agencies: Telethon, Regione Piemonte, and Italian Ministry for University and Research. The study findings were presented by Nicoletta Filigheddu, a researcher at the University of Piemonte Orientale’s Biotechnology Center.

Tuesday 30, Mar 2010

New treatment option for curing severe asthma

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New treatment option for curing severe asthmaAccording to a small study in Thorax, blocking a powerful immune system chemical that is present in large quantities in patients with the severe form of the disease can help in curing severe asthma.

It is believed that around one in ten asthmatics suffers from this severe form of asthma that usually requires progressively higher doses of steroids for controlling the disease symptoms.

The authors noted that this form of treatment can be seen as a potentially new avenue of treatment for severe asthma though further research will be required before this approach can be recommended.

Tuesday 30, Mar 2010

Latest surgical techniques and intervention can benefit people with Biceps Injury

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Latest surgical techniques and intervention can benefit people with Biceps InjuryPeople who suffer from injuries to the distal biceps tendon can expect relief from earlier surgical intervention and new surgical techniques, as per a review article published in the March 2010 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS).

Karen Sutton, MD, assistant professor at Yale Medical School and attending orthopaedic surgeon at Yale New Haven Hospital, said that latest techniques allow for smaller incisions and tendon strength can be restored to within 90 percent to 95 percent of its original strength.

It was also revealed by the study that surgery is the most effective of all options and even simpler when performed within two weeks of the initial injury.

Tuesday 30, Mar 2010

HIV patients are easy victims of osteoporosis

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HIV patients are easy victims of osteoporosisThe introduction of HAART (Highly Active Antiretroviral Therapy) may have improved the survival and quality of life for people infected with the human immunodeficiency virus (HIV-1) but this improved prognosis has also resulted in long term negative disorders, namely osteoporosis.

Osteoporosis is a multifactorial disease characterized by reductions in bone mass leading to an increased propensity to bone fractures.

A study published in the Spanish review Enfermedades Infecciosas y Microbiología Clínica [Infectious Diseases and Clinical Microbiology] revealed that the prevalence of osteoporosis in HIV-1 infected patients.

The authors said that clinical trial results are awaited with a hope to bring new evidence about the possible effectiveness of anti-osteoporotic treatment in these patients.

Monday 29, Mar 2010

Combo inhaler effective for simplifying asthma treatment

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Combo inhaler effective for simplifying asthma treatment  A new treatment option may help people with chronic asthma to manage their condition with a single prescribed inhaler that contains two medicines, as per a review.

Lead reviewer Christopher Cates, M.D., at the Community Health Sciences of St. George’s at the University of London, said that most asthma patients default on inhaled corticosteroids as inhaled steroids do not bring immediate difference to asthma symptoms.

Carlos Camargo, M.D., an associate professor of medicine at Harvard Medical School, specializes in asthma and chronic obstructive pulmonary disease, remarked that this single-inhaler therapy is an interesting approach to treat chronic asthma.

Monday 29, Mar 2010

New treatment options have improved multivisceral transplant survival rates

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New treatment options have improved multivisceral transplant survival ratesThe advent of innovative surgical techniques, novel immunosuppressive protocols, and better post-operative management has improved the survival rate of patients facing multivisceral transplant.

This finding was disclosed by researchers at the Thomas E. Starzl Transplantation Institute in a study published in the October 2009 issue of Annals of Surgery in what was the largest single-center experience of adult and pediatric intestinal and multivisceral transplantation.

The study was led by Kareem Abu-Elmagd, M.D., Ph.D., director, Intestinal Rehabilitation and Transplantation Center, Thomas E. Starzl Transplantation Institute, and professor of surgery, University of Pittsburgh School of Medicine.

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