Clomid is a popularly referred brand name for the drug Clomiphene or Clomifene. It is a selected estrogen receptor modulator which is known to increase the production of gonadotropins.  For this reason, it is commonly prescribed to women for improving their fertility. Clomiphene citrate is the main ingredient in this estrogen which stimulates the process of ovulation in women, thereby acting as a fertility aid. Chemically it is recognized as a 2-(4-(2-chloro-1,2-diphenylethenyl-phenoxy)-N,N-diethyl-ethanamine. Clomid is also popularly marketed as Serophene and Milophene.

Clomid intake is also common amongst athletes and bodybuilders as it restores the body’s natural testosterone levels that may have been affected by use of harsh and aromatizable steroids and also avoids the occurrence of gynecomastia in post cycle therapy. This steroid is highly effective and also an inexpensive compound. It is for this reason that it is so widely sought by bodybuilders and sportsmen all over the world.

Clomid is ideally a synthetic estrogen which possesses both agonist as well as antagonist properties. Chemically its structure and action is very similar to Nolvadex. However, when ingested in the body, Clomid minimizes the effect of natural estrogen in the body. Clinically it is believed to reduce the negative feedback of estrogen on the hypothalamus, enhancing the release of FSH and LSH. It is because of this mechanism that testosterone production in men is restored. This proves to be highly beneficial for athletes when they administer it at end of their steroid cycle because during the cycle, their endogenous testosterones are usually depressed. Once the anabolic effect from the body is removed, it is important to bring the level of endogenous testosterones back to normal as inability to do so might cause what is called a post-steroid crash.  In a steroid crash, a major loss in the size and the strength of the newly acquired muscle takes place. This is because in the absence of testosterone, the catabolic cortisol hormone becomes dominant. Administration of Clomid at this point, helps avoiding this crash.

For women, the best time to use it is around the contest time when the adjustment of estrogen levels is required. Women should intake this steroid only under the supervision of a physician as excessive intake may increase fat loss as well as muscularity. In some cases, it might cause troubled effects such as poor vision. However, this may take place only when dosages become exceedingly high.

For men, the best dosage is 50 to 100 mg per day. Its administration brings testosterone production to normal levels within the period of 4 to 6 weeks. The regime followed by professionals is 100 mg from day 1 to 11 and 50 mg from days 12 to 21. The restoration of testosterone levels is however, gradual. To achieve an immediate effect, Clomid is often ingested with Human Chorionic Gonadotropin (HCG) for the first two weeks after the anabolic steroid intake is discontinued. This combined intake also aids in restoring the normal ability of the testicles’ responsiveness to endogenous LH. After HCG’s administration along with Clomid is stopped, the user may continue to take Clomid for a certain period. It must be mentioned here that the use of HCG should not exceed more than 2-3 weeks as it may it may initiate the negative feedback inhibition on the hypothalamic-pituitary axis. Also Clomid intake in injectable form has an effect more long lasting in an ancillary drug program. It is also observed that if HCG and Clomid are taken periodically in a steroid cycle, the natural testosterone level can be prevented from reducing. Usage of strong androgens should be avoided for a prolonged period of time. Some bodybuilders take these drugs alternatively, sometimes even after long intervals for the fear of losing their effectiveness if taken together.

Another drug that is widely used in combination with Clomid is Proviron. Proviron is an oral DHT which considerably lowers the aromatase activity in the body, thereby raising the estrogen to androgen ratio. Clomid’s association with Proviron has been proved to be extremely effective. However, it can also be combined with certain specific inhibitors such as Aromasin, Femara, and Arimidex.

A factor that makes Clomid such a popular drug is that it is very safe. Bodybuilders reporting its side effects (after excessive intake) have been very few.  Some common ones include nausea, dizziness, headaches, and hot flushes. Hence over-dose is strictly not recommended. This popular estrogen is widely available in the market under a vast range of brand names. Its popular forms are tablets and injectables.