Combination of Antibiotic and Steroids for Sinus TreatmentAccording to a study of JAMA, a combination of antibiotic and steroids is useful for treating acute sinusitis with less than severe symptoms.

Acute sinusitis is a sinus infection that is a common clinical problem with symptoms similar to other illnesses, and is often observed in general masses. Researchers showed that anti-inflammatory drugs such as topical steroids are quite beneficial in cases of acute sinusitis.

To determine the effectiveness of the antibiotic amoxicillin and topical steroid budesonide in acute maxillary sinusitis, Ian G. Williamson, M.D., of the University of Southampton, England, and colleagues conducted a double-blind randomized placebo-controlled trial.

240 adults were divided into four groups, antibiotic and nasal steroid (500 mg of amoxicillin 3 times per day for 7 days and 200 ìg of budesonide in each nostril once per day for 10 days); placebo antibiotic and nasal steroid; antibiotic and placebo nasal steroid; placebo antibiotic and placebo nasal steroid.

All this showed that the nasal steroids were effective to patients who had less severe symptoms of sinusitis.