According to a new study that was published in an issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), chronic obstructive pulmonary disease (COPD) patients using inhaled corticosteroids are likely to have a considerably reduced mortality risk.

It was revealed by the researchers that patients receiving inhaled corticosteroids within a period of 30 days of hospital discharge had a 25 percent reduced all-cause mortality rate. It was also noted that patients using steroids paired with beta-agonists saw a fall in cardiovascular-related deaths by 38 percent.

From News-Medical.Net:

Researchers also found a 23 percent reduced risk of death when comparing the effects of inhaled steroids with bronchodilators in patients in the 65+ group. In all cases, the most significant results were found when inhaled corticosteroids were administered within the first 30 days following hospital discharge.

“Our results indicate that the effect of inhaled corticosteroids is relatively short-term and that those currently using it are relatively better protected, ” said Dr. Macie. “Inhaled corticosteroids should be prescribed as soon as clinically indicated. By treating COPD with inhaled corticosteroids, we have the potential to reduce the effect and prolong life.”

“The findings from this study are intriguing for clinicians and point to the need for further research to define the role and mechanisms of the effect of inhaled corticosteroids on both cardiovascular and respiratory mortality,” said W. Michael Alberts, MD, FCCP, President of the ACCP.

Author Christine Macie, MD, FCCP, Cambridge Hospital, Ontario, Canada, said that COPD is an underrated lung ailment that has associated lung disease.

Tags: chronic obstructive pulmonary disease, COPD, corticosteroids, inhaled corticosteroids

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