Monday 15, Jun 2009
Corticosteroids advantageous over Remicade for Induction of Remissions in Patients with Ulcerative Colitis
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According to a New Report from Decision Resources, one of the leading research and advisory firms in the world for pharmaceutical and healthcare issues, Abbott/Eisai’s Humira will earn the Gold Standard Status for Ulcerative Colitis in 2012.
It was found by Decision Resources that surveyed gastroenterologists have been able to ascertain the effect of a therapy on induction of remission. This effect is regarded as an important attribute in influencing decisions of the researchers in moderation to severe ulcerative colitis.
It was revealed during the relevant studies and clinical data that corticosteroids have an advantage over Remicade in this attribute.
From Bio-Medicine.Org:
The new report entitled Ulcerative Colitis: Opportunity Awaits Therapies That Treat Moderate to Severe Disease More Effectively Than Infliximab finds that a drug that maintains remission in a higher percentage of patients with moderate to severe ulcerative colitis than infliximab at one year would earn a 30 percent patient share in the United States and a 15 percent patient share in Europe, according to surveyed U.S. and European gastroenterologists.
In 2008, Decision Resources’ proprietary clinical gold standard for ulcerative colitis was prednisone. Based on available data and expert opinion, Abbott/Eisai’s Humira (adalimumab) will earn gold-standard status for ulcerative colitis in 2012, following its approval for the indication in 2011. Interviewed experts believe that adalimumab has potential to be superior in maintenance of remission when compared to infliximab.
Decision Resources Analyst Benjamin Guikema, Ph.D. remarked that adalimumab is believed to be more effective than infliximab with regard to the maintenance setting. Furthermore, adalimumab is able to offer superior safety and tolerability when compared to other available drugs in the market.
Guikema also remarked that Adalimumab comes with a minimal risk of prominent organ toxicity that gives it a noteworthy advantage over all other present-day therapies.
These findings will surely give the deserving importance to steroids in the world of medicines and health ailments.
Tags: adalimumab, corticosteroids, gastroenterologists, remicade, severe ulcerative colitis, steroids, ulcerative colitis
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