According to scientists from the UT Southwestern Medical Center, patients suffering from pneumonia can get great relief when corticosteroids are added to the traditional antimicrobial therapy.

In a study available online, researchers at UT Southwestern show that mice infected with a type of severe bacterial pneumonia and treated with antibiotics and steroids recovered faster and had lesser lung inflammation than mice treated with antibiotics alone.

From News-Medical.Net:

“Some people might think that if you give steroids, it would counteract the effect of the antibiotic,” said Dr. Robert Hardy, associate professor of internal medicine and pediatrics and the study’s senior author. “But it turns out you need the antibiotic to kill the bug and the steroid to make the inflammation in the lung from the infection get better. The steroids don’t kill the bugs, but they do help restore health.”

Pneumonia is a lung infection typically characterized by breathing difficulties and spread by coughing and sneezing. Symptoms include headache, fever, chills, coughs, chest pain, sore throat and nausea. Pneumonia caused by the Mycoplasma pneumoniae bacterium is generally a less severe form of the disease that can occur in any age group. It accounts for 20 percent to 30 percent of all community-acquired pneumonia cases.

Dr. Hardy said, “”It turns out that the group that got both the antibiotic and the steroids did the best”.

The study results possibly suggest a potentially new and effective therapy not only for treating patients with pneumonia but also for helping patients in the midst of an asthma attack due to M pneumoniae infection.

Tags: corticosteroids, lung inflammation, pneumonia, steroids

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