Injecting triamcinolone, the corticosteroid, directly into the eye can possibly slow down the progression of diabetic retinopathy, which is a complication of diabetes that may result in vision loss and blindness.

This finding was presented in a report in the December issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

Proliferative diabetic retinopathy is a complication that occurs when new blood vessels form on the optic disc or another retina component.

From Sciencedaily.com:

Corticosteroids have been shown to interfere with the creation of new blood vessels, possibly by reducing the production of compounds that spur their growth, the authors note. However, steroids are also associated with other eye diseases.

“Use of this intravitreal [injected into the eye] corticosteroid preparation to reduce the likelihood of progression of retinopathy is not warranted at this time because of the increased risk of glaucoma and cataract associated with intravitreal steroid use,” the authors write. “Any treatment to be used routinely to prevent proliferative diabetic retinopathy likely needs to be relatively safe because the condition already can be treated successfully and safely with panretinal photocoagulation. Nevertheless, further investigation with regard to the role of pharmacotherapy for reduction of the incidence of progression of retinopathy appears to be warranted.”

The study was conducted by Neil M. Bressler, M.D., of Johns Hopkins University School of Medicine, Baltimore, and colleagues in the Diabetic Retinopathy Clinical Research Network conducted a study involving 840 eyes of 693 participants having macular edema.

Tags: corticosteroid, Diabetic retinopathy, steroid, triamcinolone

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