Duchenne Muscular Dystrophy treatable with corticosteroidsCorticosteroids can be considered as a first-line therapy for treating Duchenne Muscular Dystrophy (DMD), according to a new practice guideline published in the Neurology, the scientific journal of the American Academy of Neurology. It was suggested during the study that patients suffering from the ailment can experience great relief when corticosteroids are administered to them.

Two corticosteroids, prednisone and deflazacort, were recommended as potential treatment methodologies, as they have the unique ability to slowdown the rate of muscle deterioration leading to reduced effects of DMD.

Richard T. Moxley III, MD, of the University of Rochester in Rochester, N.Y. and lead author, said that corticosteroids are the only effective drugs for providing improvements in children with DMD.

From News.Bio-Medicine.Org:

The guideline authors reviewed all available research for the use of corticosteroids in the treatment of Duchenne muscular dystrophy. Corticosteroids are man-made drugs that are similar to the body’s hormone cortisone. Two corticosteroids, prednisone and deflazacort, were found to slow the rate of muscle deterioration, and are recommended as potential treatments to minimize the effect of Duchenne muscular dystrophy.

Prednisone was found to help muscle strength and function and should be offered as a treatment option. Deflazacort, a drug similar to prednisone, is also recommended as a treatment option but is not available in the United States at this time.

“Corticosteroids are the only effective drugs in providing improvements in children with Duchenne muscular dystrophy,” said lead author Richard T. Moxley III, MD, of the University of Rochester in Rochester, N.Y.

It was however remarked that pros and cons of steroid treatment must be evaluated carefully so that complete benefits can be attained.



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