Critical ethnic disparities in hormonal activity are ignored by doping tests and steroid (testosterone) doping tests should be scrapped for international sporting events, as per a research published ahead of print in the British Journal of Sports Medicine.

The research suggested that a single indiscriminate threshold for picking up steroid abuse in international sport is no fit for the purpose.

From News-medical.net:

Evidence of abuse is determined by the testosterone: epitestosterone ratio, or T:E ratio for short, in the urine. The threshold is set at above four for everyone, and confirmed by chemical analysis (gas chromatography).

To highlight the inadequacy of the current test, the researchers tested the steroid profiles of football players of different ethnicities, after they had deliberately added steroid to their urine samples.

They used gas chromatography, and took account of a variation (polymorphism) in the UGT2B17 gene.

Previous research has indicated that variations in this gene account for some of the differences in the urinary T:E ratio between men of white and Asian ethnic backgrounds. The gene affects metabolism, and therefore the rate at which testosterone is passed out of the body into the urine.

Testosterone derivatives and other hormones, which have the potential to enhance testosterone levels, are among the most widely abused performance enhancing drugs in sports as per the WADA.

Tags: performance enhancing drugs in sports, steroid, steroid profiles, testosterone

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