Growth hormone production traced to human brainAccording to an article published in the Proceedings of the National Academy of Sciences citing a discovery by scientists, the human brain produces growth hormone in human beings.

It was found by the researchers that growth hormone (GH) is produced within a structure deep inside the brain that is involved in memory and emotion, known as hippocampus. It was also found that growth hormone production is more in females than males, and more in adults.

From News-Medical.Net:

The scientists also found that more growth hormone is produced in females than in males, and more in adults. More growth hormone was also produced in response to estrogen. The study has implications for menopausal women using estrogen replacement therapy and for athletes taking growth hormone and anabolic steroids to increase muscle mass.

The scientists suspect that reasoning and mood may also be affected by these differences in the amount of growth hormone in the brain.

“Growth hormone has been associated with growth of muscles and bones, and the production of it was believed to lie mainly in the pituitary gland,” said co-author Ken S. Kosik, co-director of the Neuroscience Research Center at the University of California, Santa Barbara. “No one had thought too much about what growth hormone might be doing in the brain. Hormones in the brain may not be obvious compared to what they are doing in the rest of the body.”

First author Christine P. Donahue. Donahue, formerly a postdoctoral fellow of Ken Kosik and an instructor in the Department of Neurology at Harvard Medical School, said that GH production in men is positively stimulated with stress and is dependent on the estrogen level in women.