Hay fever and asthma patients can expect a good surprise in the times to come if a new drug, RPL554, is able to live up to expectations of effectively treating respiratory diseases but without many of the side-effects most presently-available drugs produce.

The trial to check efficacy of RPL554 started in November 2009 and is expected to be completed by this summer.

From News-Medical.Net:

Current treatments for asthma and hay fever sufferers are beta-agonists, which open up the airways, and inhaled steroids, which dampen down the inflammation that causes irritation – they are either taken together or singly.

But they have serious side effects, including possible harm to the cardiovascular system and the ‘shakes’ reported by many patients from excess use.

Experts say little progress has been made recently with alternative, effective and practical treatment options for a wide range of people with asthma and hay fever and by combining anti-inflammatory properties and the ability to overcome airway narrowing in a single long-lasting dose via the nose, RPL554 could offer real hope of a significant breakthrough.

According to Dr. Clive Page, chairman of Verona Pharma and a professor of pharmacology at King’s College London, RPL554 is the sole molecule expected to have a low side effect profile. Once-a-day treatment with it can provide significant relief to asthma and hay fever patients.

Tags: Asthma, hay fever, RPL554, steroids

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