During a study in which comparisons were made between cromolyn and inhaled steroid treatment in context to treating asthma, it was found that inhaled steroids are better than cromolyn.

This study was conducted by James Guevara, M.D., of the University of Pennsylvania School of Medicine and colleagues and suggested that adults and children with asthma can exercise better control over asthma with inhaled corticosteroids than cromolyn.

From News.Bio-Medicine.Org:

Cromolyn’s manufacturer has changed several times during the past two decades, which may also explain why the drug’s popularity has waned, Storms said. The succession of companies “did not spend one dollar in research in the past 20 years to study cromolyn. All of the data are old and most are forgotten,” he said.

The Cochrane reviewers examined 17 studies involving 1279 children and eight studies involving 321 adults with asthma. They found no differences in serious side effects between those using the steroids and those using cromolyn, but acknowledge that adverse effects were reported inconsistently.

Guevara and colleagues conclude that inhaled corticosteroids were superior to cromolyn regardless of the severity of the asthma. They suggest the results are so decisive that future studies comparing the two types of drugs “may not be warranted.”

The study pointed out that asthmatic patients on inhaled steroids (such as the brand names Pulmicort, Flovent, and Beclovent) had fewer severe asthma flare-ups on a yearly average basis when compared to patients on cromolyn (sold under the brand name Intal).

It was also suggested that patients on steroids scored considerably better on tests of lung function and made less use of asthma inhalers.

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Tags: Asthma, asthma inhalers, asthma treatment, beclovent, cromolyn, flovent, inhaled cromolyn, Inhaled steroids, intal, pulmicort, steroids

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