As per a recent study, steroid treatment is an effective form of treatment for patients suffering from sudden sensorineural hearing loss (SSNHL). It initially occurs in one ear and generally causes a 30+ decibel (dB) hearing loss at three consecutive frequencies within a time period of three days.

Scientists from Spain presented a new study which evaluated the effect of intratympanic steroid injections in patients with SSNHL. Studies was conducted on 50 patients diagnosed with unilateral (affecting one ear) SSNHL due to unidentified reasons. Hearing improvement of 15 dB or more in PTA was noted in 32 cases (64 percent) by the intravenous treatment.

There were no statistical differences in age, sex ratio, time of onset to therapy, presence of vertigo and tinnitus, initial hearing level, and final hearing level after intravenous treatment between the two groups.

From medical news today:

As a result of its anti-inflammatory effect, high-dosage systemic steroid therapy is currently the mainstay of the treatment for SSNHL. Despite oral or intravenous steroid therapy for two weeks, approximately 30-50 percent of patients show no response. Animal studies have found that intratympanic steroid injections, introducing steroids through the tympanic membrane, results in reduced systemic steroid toxicity and higher perilymph steroid level selectively. Past research has focused on use of these injections as a secondary-line therapy in SSNHL refractory cases. Other clinicians promote its use as first-line therapy in all SSNHL cases. Nevertheless, few controlled studies have been published comparing the results between intratympanic steroid treatment and other approaches.

The intratympanic methylprednisolone significantly improved the outcome of SSNHL by non-randomized clinical trial showed after intravenous steroid treatment. The therapy including intratympanic steroids was termed as a useful and safe therapy for SSNHL cases that are refractory to standard treatments.

Randomized prospective clinical trials were defined as the researchers suggested that the number of injections, the types of steroids, and the most adequate doses must be definite in their nature. Evidence-based treatment for idiopathic SSNHL was also established by this study. Evaluated results compared initial therapy for SSNHL and steroids that were administrated systemically or by intratympanic injections were mush effective.

Tags: decibel, intratympanic, intravenous treatment, methylprednisolone, sudden sensorineural hearing loss (SSNHL)

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