Researchers at the University of Bristol are looking for volunteers to find out if hydrocortisone, a drug affecting stress system of the body, could help people with depression and not responding to present forms of treatment.

It is believed that Severe or recurrent depression affects 3-5 percent of the population and 10-30 percent of this population do not respond to the present-day treatment options.

Dr Andrea Malizia leading the team of Bristol researchers has a long-standing clinical and research interest in treatment resistant depression and spearheads a specialist outpatient service at the Bristol Royal Infirmary.

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