According to a new study conducted by researchers from the Ohio State University Medical Center, a substance created by the immune cells play a pivotal role in disease progression in animals, closely mimicking multiple sclerosis. The study found out that blockage of this molecule known as macrophage migration inhibitory factor (MIF) can effectively prevent disease progression.

Though MIF may be considered of less importance for MS initiation, it is imperative for the progression of multiple sclerosis, as per principal investigator Caroline C. Whitacre, Professor of molecular virology, immunology and medical genetics.

From News-Medical.Net:

“Our results suggest that MIF may be less important for initiating MS, but that it may be necessary for MS progression,” says principal investigator Caroline C. Whitacre, professor of molecular virology, immunology and medical genetics.

“These findings indicate that in the future we can perhaps use MIF levels to predict the onset of a relapse. But more importantly, perhaps this study will lead to drugs that can halt the course of MS by blocking the action of MIF.”

The findings clearly suggested that MIF levels can be used for predicting the onset of a relapse. Most importantly, the study is believed to create new roadways for halting the course of MS by blocking MIF activities.

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Tags: disease progression, macrophage migration inhibitory factor, MIF, multiple sclerosis

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