Protein behind Chronic Rhinosinusitis with Polyps identifiedVascular endothelial growth factor (VEGF), a protein necessary for normal blood vessel growth and stimulating blood vessel growth, has been found to be behind cell overgrowth in the development of polyps characterizing one of the most severe forms of sinusitis.

The finding was revealed by researchers at the Johns Hopkins and appeared in an issue of the American Journal of Respiratory and Critical Care Medicine.

Jean Kim, M.D., Ph.D., assistant professor in the Departments of Otolaryngology and Allergy and Clinical Immunology at the Johns Hopkins University School of Medicine, and a researcher at the Johns Hopkins Allergy and Asthma Center at the Johns Hopkins Bayview Medical Center, said that this kind of sinusitis isn’t subtle.