Rituximab can be effective for curing membranous nephropathyRituximab can prove its worth when it comes to treating patients with membranous nephropathy, a kidney disorder, according to findings appearing in the April 2009 print issue of the Clinical Journal of the American Society of Nephrology (CJASN).

Present treatments for this disorder are limited to calcineurin inhibitors, steroids, and chemotherapeutic agents, all of which have some side effects.

Andrew Bomback, MD (University of North Carolina Kidney Center), and his colleagues after conducting the first systematic review of rituximab use in patients with membranous nephropathy compared the effect of rituximab therapy for treating patients struggling against nephropathy.

From News-Medical.Net:

To investigate rituximab’s potential, Andrew Bomback, MD (University of North Carolina Kidney Center), and his colleagues conducted the first systematic review of rituximab use in patients with membranous nephropathy. They collected and analyzed all of the data available on rituximab therapy in this patient population. They found 21 articles to date, all of which were either case reports or case series without controls, meaning that patients taking rituximab were studied for a certain length of time but were not compared with patients not taking the drug.

Dr. Bomback said that further studies are still required to prove value of this drug and usage must be done only in research settings at present.


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