As per the biggest study of its kind, rituximab that is used to treat rheumatoid arthritis (RA) is safe and effective at the same time. The results of this study were presented for the first time at the Annual European Congress of Rheumatology, EULAR 2005, in Vienna.

It was remarked by lead author, Professor Paul Emery from the University of Leeds in the UK, of the DANCER Study (Double blind placebo controlled dose ranging study) that rituximab is very much effective and better option than a placebo.

From News-Medical.Net:

Professor Paul Emery from the University of Leeds in the UK led the DANCER study (Double blind placebo controlled dose ranging study), designed to confirm the efficacy of rituximab for the treatment of patients with active RA who have failed to improve on one or more disease modifying anti-rheumatic drugs (DMARDs). Rituximab targets a specific type of immune cell and helps to control inflammation and pain.

The DANCER study involved 465 men and women who had had arthritis for about 10 years. It examined the relative efficacy of two different dose levels of rituximab, as well as the role of anti-inflammatory drugs, glucocorticoids (steroids), in the treatment programme.

Professor Emery said that findings of this study clearly suggest that rituximab is safe and well-tolerated for patients with rheumatoid arthritis.

Tags: glucocorticoids, placebo, Rheumatoid arthritis, rituximab, steroids

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