Sex steroids and irritability associated with menopauseThere is a possible link between irritability and perimenopausal and postmenopausal women but there are not any study results or evidence suggesting an association.

A study examining association between menopause with sex steroids, gonadotrophins, prolactin and thyroid hormones and with samples including of 163 women, with a mean age of 55.1 years (SD = 5.7) in relation to 124 postmenopausal and 26 perimenopausal women, suggested that a high score is visible on inward and outward irritability scales in women with chronic disease.

Though not linked directly with menopause, it could have been partially influenced by the growing age of menopausal women.

The results of this study are seen by many as evidence that suggests a possible link between menopause and outward irritability.