Significance of T/E ratio in steroids use T/E Ratio stands for testosterone / epitestosterone ratio. It is used to determine the relative proportion of testosterone and epitestosterone. The normal level is set at a 1:1 ratio.

T/E ratio is an important indicator of any pathological condition or external administration of any synthetic hormones. It is done by measuring the levels of testosterone glucuronide (TG) and epitestosterone glucuronide (EG) in the urine. If testosterone levels increases, TG also increases. EG, on the other hand, remains unaffected even with increase testosterone metabolism.

However, did you know that if you have flu, it might affect the result of your T/E ratio? Additionally, if you try to get the extra edge in a Friday night game, it might also alter the normal T/E ratio.

Epitestosterone is normally higher in male adolescents compared to adult males. Although epitestosterone is not considered as a performance-enhancing drug, it is banned by many sporting authorities because it can mask the presence of high levels of testosterone in the body, if the standard T/E ratio is used.

Other drugs such as NSAIDs and opioid analgesics may also affect the ratio by increasing the rate of excretion of epitestosterone metabolites.