According to a study, some children suffering from asthma are genetically less responsive to inhaled corticosteroids.

It was remarked by researcher Gregory Sawicki, M.D. of Children’s Hospital in Boston, that there can be many reasons for this finding.

Dr. Sawicki noted that many studies of asthmatic adults have already suggested that even rigorous use of inhaled steroids does not lead to well controlled asthma in all adults.

From News-Medical.Net:

Of the 914 children in the study, inhaled steroids were recommended for 435 who had persistent asthma, meaning they had symptoms on a regular basis. Among children who weren’t recommended for inhaled steroid treatment, most reported well-controlled asthma. Among those recommended for inhaled steroid treatment, 44% reported consistently using the medicine; 35% said they intermittently used the medicine and 21% said they didn’t use it at all.

“The majority of children with mild asthma are less likely to have symptoms as they get older and may not need to be on daily steroids,” Dr. Sawicki said. “The flip side is that if a child has poor asthma control, the parents and doctor need to make sure the child is adhering to their inhaled steroid treatment. But variation in response to inhaled steroids, as other medications, is well described.”

This data came from the Child Asthma Management Program Continuation Study (CAMPCS), one of the largest groups of children with mild to moderate asthma in the nation who have been followed over 10 years.

Tags: Asthma, Inhaled steroids, steroid treatment, steroids

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