Steroid-Based Therapy Induce Hair GrowthA kind of steroid therapy has induced hair growth in more than 90% of patients with alopecia universalis. In the clinical evaluation of Dr. Kiumars Pirkalani of Mehr Medical Group in Tehran, Iran, the therapy starts with methotrexate and triamcinolone and then progresses through some of the same drugs used to treat rheumatoid arthritis.

According to Dr. Pirkalani, conventional therapies for alopecia areata and its variants have proven unsatisfactory. Local irritants, such as diphencyprone and dithranol, induce hair growth in no more than half of patients and many of them cannot tolerate the therapies.

During the study, the researchers developed a multistep approach to treat alopecia universalis, by employing two or more drugs. Doctor Pirkalani said that 94% or 102 of 109 patients have responded to weekly triamcinolone and methotrexate.