Steroid nasal spray may relieve seasonal allergy symptoms better than an oral antihistamine. This was the finding in the study made by Dr. Robert Naclerio and colleagues from University of Chicago. The team compared the effectiveness of fluticasone(Flonase),a corticosteroid nasal spray, with loratadine (Claritin),a nonsedating antihistamine, for treating ragweed allergy on an as-needed basis.

Participants who used the inhaled steroid experienced significantly fewer allergy symptoms and reported less impact on their quality of life than those who took the antihistamine.

From Bio-Medicine:

Researchers say, that a steroid nasal spray may relieve seasonal allergy symptoms better than an oral antihistamine. Dr. Robert Naclerio and colleagues from University of Chicago,compared the effectiveness of fluticasone(Flonase),a corticosteroid nasal spray, with loratadine(Claritin),a non-sedating antihistamine, for treating ragweed allergy on an as-needed basis.

Participants who used the inhaled steroid experienced significantly fewer allergy symptoms and reported less impact on their quality of life than those who took the antihistamine. During the four-week study, 88 participants took either the steroid nasal spray or antihistamine on an as-needed basis. They kept a daily diary of their allergy symptoms and completed a quality-of-life questionnaire.

Researchers looked for chemical evidence of allergic reaction, such as eosinophils, in participants’ blood. Eosinophils are white blood cells involved in defending the body from allergens. For best results, experts generally recommend that you use either an inhaled steroid or an antihistamine on a continuous, long-term basis.

The study suggests that patients with seasonal allergies must until symptoms appear before taking allergy medications. The team also emphasized that steroid nasal spray works better than inhaled corticosteroids, antihistamines in allergic symptoms. Although most doctors prescribe inhaled corticosteroids and antihistamines to patients, these medications are not effective in blocking the allergic response once it has started. Steroid nasal spray is best treatment for allergic symptoms on as-needed basis.

Tags: antihistamine, inhaled corticosteroids, seasonal allergy, steroid spray

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