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Tuesday 08, Nov 2011

  Harm to brain when steroids are given to premature infants

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Preterm infants who are treated with glucocorticoids could be at a growing risk for damage to the cerebellum in the brain, according to a recent study by scientists from the University of California.

Glucocorticoids are usually administered to premature infants to facilitate lung maturation and normalization of breathing and blood pressure.

The study, ‘Preterm Cerebellar Growth Impairment After Postnatal Exposure to Glucocorticoids’, is published in the journal Science Translational Medicine.

Saturday 31, Jul 2010

  Topical steroids beneficial for acute psoriasis patients

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Topical steroids beneficial for acute psoriasis patientsAccording to a study conducted by Alexander Kreuter, M.D, from Ruhr University of Bochum, Germany, and colleagues, the application of topical corticosteroids and maintaining with a less potent agent in the short-term can help patients afflicted with intertriginous psoriasis (IP).

The finding nullified all myths associated with side effects in context to use of topical corticosteroids in the long run.

The finding is expected to offer implications for providing significant relief to intertriginous psoriasis patients who often have complains about intense itching, irritation from sweating, and soreness.

Monday 19, Jul 2010

  Acute Psoriasis Patients beneficiaries of topical corticosteroids

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Acute Psoriasis Patients beneficiaries of topical corticosteroidsPatients with intertriginous psoriasis (IP) can expect relief coming their way when they are treated with an application of topical corticosteroids in the short term and maintenance with a less topical agent, as per a study conducted by Alexander Kreuter, M.D, from Ruhr University of Bochum, Germany, and colleagues.

The study also nullified all myths of side effects associated with use of topical steroids in the long run and the findings are considered to have major implications for treating intertriginous psoriasis patients who regularly complain of intense itching, soreness, and irritation from sweating.

The study suggested that application of corticosteroids for acute disease in the short run followed by maintenance treatment with any of the less potent agents can be classified as a reasonable approach for treating IP patients.

Friday 25, Jun 2010

  Patients afflicted with acute psoriasis benefit from topical corticosteroids

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Patients afflicted with acute psoriasis benefit from topical corticosteroidsAn application of topical corticosteroids and maintenance with a less potent agent in the short run could help patients with intertriginous psoriasis (IP), according to a study conducted by Alexander Kreuter, M.D, from Ruhr University of Bochum, Germany, and colleagues.

The study refuted all myths about side effects related with long-term use of topical corticosteroids.

Monday 17, May 2010

  Continuing steroid doses associated with cerebral palsy

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Continuing steroid doses associated with cerebral palsyRepeated courses of a corticosteroid called betamethasone that is used for improving the survival of unborn premature babies could possibly increase the risk of cerebral palsy in those children.

This finding was revealed as part of results from a multi-center study, which was funded by the National Institutes of Health and led by Ronald Wapner, M.D., professor of obstetrics and gynecology, Columbia University Medical Center and attending obstetrician and gynecologist at NewYork-Presbyterian Hospital/Columbia.

This research was supported by the National Institute of Child Health and Human Development of the National Institutes of Health and the study results were published in an issue of the New England Journal of Medicine.

Wednesday 07, Apr 2010

  Multiple courses of steroids can guard lungs of preterm babies

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Multiple courses of steroids can guard lungs of preterm babiesMultiple courses of steroids such as betamethasone can prove effective for enhancing the survival rate of babies to nursing women in preterm labor, as per a recent study. It was further revealed in the study that repeated courses of steroids do not bring a negative impact on brains of the babies as previously thought.

Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study, said that nursing mothers avoiding steroid treatment can experience babies needing ventilation.

Amin further remarked that there is still a need to conduct future studies before this treatment can be termed as completely safe and effective.

Thursday 11, Feb 2010

  Safer preemie lung treatment options analyzed

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safer-preemie-lung-treatment-options-analyzedThe use of steroids for treating preemies between 28-32 weeks of age, does not lead to any harm. This finding was disclosed in an issue of Pediatrics and suggested that brains of babies remain virtually unaffected by steroid administration, a fact that nullifies the past belief that repeated courses of steroids in the womb lead to brain damage.

This finding is expected to offer crucial insights to members of the medical fraternity besides offering relief to expecting mothers.

Wednesday 06, Jan 2010

  Continued steroid doses to premature infants linked to cerebral palsy

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cerebral-palsy

Repeated courses of a corticosteroid called betamethasone, which is indicated for improving the survival of unborn premature babies, can increase the risks of cerebral palsy in those children.

This finding was disclosed as per results from a multi-center study, funded by the National Institutes of Health and led by Ronald Wapner, M.D., professor of obstetrics and gynecology, Columbia University Medical Center and attending obstetrician and gynecologist at NewYork-Presbyterian Hospital/Columbia.

The study results were published in an issue of the New England Journal of Medicine.

It was remarked by Dr. Wapner that since weekly courses had no long-term benefits and may potentially harm the child, medical doctors must not administer multiple weekly courses of corticosteroids.

Saturday 03, Oct 2009

  Preemie lung treatment options prove safe

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Preemie lung treatment options prove safeAccording to findings of a study in an issue of Pediatrics, preemies between 28-32 weeks of age are not harmed by a treatment option that is no longer used to help in maturing lungs. The concerned study revealed that babies’ brains remain virtually unaffected; a fact that overrules the previously believed fact that repeated courses of steroids in the womb may lead to brain damage.

It is believed that this study would provide new insights to further clinic studies in the same regard.

Wednesday 30, Sep 2009

  Steroids use in preemies linked to cerebral palsy

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Steroids use in preemies linked to cerebral palsy  According to a multi study funded by the National Institutes of Health (NIH), steroids used to improve the lung development of premature babies could actually increase their risk for cerebral palsy.

Steroids, specifically, a corticosteroid called betamethasone is a drug that has shown to decrease neonatal mortality. It is given to women at risk of giving birth prematurely in order to hasten the development of the baby’s lungs.

Obstetrician – gynecologists often practice repeated course of steroids administration every week of up to 10 to 11 times. However, NIH representatives were so concerned with the safety that they wanted to limit the repeated courses for patients enrolled in clinical trials.

A study was performed by the Maternal-Fetal Medicine Network involving infants from the Morgan Stanley Children’s Hospital and 12 other sites around the country. Multiple courses of steroids were given to mothers and by the time the children reached the age of two or three years old, it was found that 6 out of 248 children in the treatment group were diagnosed with cerebral palsy while only 1 out of 238 children in the placebo group was diagnosed with the disease.

Dr. Wapner, head of the study advised that doctors multiple doses of steroids should not be administered since it could potentially do more harm than good.

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