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Sunday 29, Jan 2012

  King Mo will not appeal positive steroid test

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Former Strikeforce light heavyweight champion Muhammed Lawal is not expected to file an appeal with the Nevada State Athletic Commission (NSAC).

Lawal tested positive for the anabolic steroid Drostanolone following a Jan. 7, 2012, win over Lorenz Larkin.

From Mmamania.com:

Drostanolone, also found in previous drug test results from Josh Barnett and Hermes Franca, is popular among athletes and competitive bodybuilders because its “anti-estrogenic properties make it a very effective cutting agent.”

But “King Mo” insists he “had no intent of taking any illegal substance.”

That’s according to his manager Mike Kogan, who told the MMA Hour (via MMA Fighting) that Lawal ingested “a supplement called S-Mass Lean Gainer by Rock Solid, which Lawal said he bought at a Max Muscle store in California and used only sporadically for ‘rehab stuff.’”

“When I went to Max Muscle, I figured you can’t buy steroids at a Max Muscle. It’s a chain store,” he said. “That’s like going to a grocery store and buying something illegal there. I guess that’s the mistake I made. When I looked at the bottle, it just had a bunch of numbers on it. It had the ingredients. I didn’t see anything that looked illegal on the bottle, to be honest with you,” Lawal said.

Saturday 28, Jan 2012

  Dianabol

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Dianabol is one of the most common oral steroids called Methandrostenolone. A derivative of testosterone, Dianabol is one of the most popular steroids and exhibits strong anabolic and moderate androgenic properties. Its easy usage and effectiveness is what makes this steroid widely accepted. Its chemical name is 17a-methyl-17b-hydroxy-1,4-androstadien-3-one 1-Dehydro-17 a methyltestosterone.

Dianabol, or D-bol as it is commonly addressed, is widely used because of its remarkable ability to build muscle strength in a relatively very short span of time. It also possesses a multifaceted approach in building the muscles without causing and loss of weight. The Methandrostenolone contained in Dianabol is its most active ingredient and acts in an ergogenic manner when orally administered.

Most common users of D-bol are athletes and particularly bodybuilders seeking maximum muscle mass within minimum time limits. Dianabol contains a powerful anabolic agent which upon entering the body, increases the synthesis of the proteins and also causes the retention of nitrogen in it. Increase in the levels of proteins helps in the balancing of nitrogen in the body which further aids in the development of adaptogenic properties in it. This allows the body to adapt according to increased workloads as well as fatigue.

Dianabol’s primary role is that it lets the acquired muscle protein in the body to stay. This anabolic drug is also known to show considerable growth in body insulin, a hormone produced in the liver. This creates a soothing effect in the body and users of this effective steroid are often seen talking about improved sleep, lower stress levels, better appetite and feeling of relaxation despite outside pressures. This is particularly the result of increased normalizing effect of Dianabol after the RNA synthesis during stress. However, in bodybuilders, it prevents the body from avoiding catabolic stress which helps them perform at a higher level and also recover fast after tedious training regime.

What makes D-bol so sought after is its ability to stimulate strength gain in the muscle in a very direct way. During phases of heavy physical and mental stress & irregular training and caloric retention, this anabolic steroid creates a temporary anabolic state which stops the breaking down of protein so that it releases amino acids in other muscles of the body, making them more intact and strong.

Despite being such a popular muscle-mass building steroid, Dianabol is not very often used in pre-contest cycles. This is particularly because it increasingly aromatizes to estrogen and causes high retention of fluid in the body. It is always advised to administer this anabolic drug in limited amount as high dosage over an extended period of time can strain the functioning of the liver. Some other apparent effects that might occur owing to heavy dosage such as 100mg per day are gynecomastia, acne, oily skin, testicular atrophy, deepening of the voice, hair loss, high blood pressure and loss of libido in some cases.

The dosage of Dianabol is variable. For men, it is advisable to start with 10mg per day which can be increased up to 25mg per day. Women wanting to take Dianabol with an intent to cut fat and gain muscle strength should start with 5mg per day and must not go beyond 10mg in a day.

The active life of this drug is about 3-5 hours. Since it is rapidly absorbed in the digestive juices in the stomach, it is best advised to take it with food and large amount of water to avoid abdominal cramps. The advanced testing systems nowadays can identify metabolites of Dianabol in the urine samples of the user, up to 4 weeks after the last dose is administered.

Being a popular drug, Dianabol is easily available. There are numerous sites on the internet which sell this steroid from where it can be ordered with or without a medical prescription. One should bear in mind that Dianabol is a highly potent drug and hence should be taken only under the supervision of a physician.

Wednesday 25, Jan 2012

  HCG

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Human chorionic gonadotropin, more commonly referred to as HCG is a glycoprotein consisting of a peptide chain of 244 amino acids. Its molecular weight is 36.7 kDa.

HCH is heterodimeric in nature composed of an α (alpha) subunit identical to that of follicle-stimulating hormone (FSH),luteinizing hormone (LH) and  thyroid-stimulating hormone (TSH) and a β (beta) subunit which forms a distinctive feature of HCG. It’s α (alpha) subunit has a peptide chain of 92 amino acids and β-subunit consists of 145 amino acids. This peptide chain is encoded by six highly-homologous genes, arranged in tandem with pairs inverted on its chromosome. These two subunits are known for creating a hydrophobic core which is surrounded by a high surface area-to-volume ratio, approximately 2.8 times that of that sphere. Most of the amino acids on the outer side are hydrophilic.

This glycoprotein hormone is primarily released in the body when a woman is pregnant. It is released by the developing embryo in the uterus and then later by the syncytiotrophoblast which is actually a part of the placenta surrounding the embryo. Some cancerous tumors are also known to cause the production of this hormone. Hence if it is found in high measures in a patient who is not pregnant, it plays an important role in help rule out any risk of cancer. However, it has still not been found whether the production of HCG is a contributing factor or a result of tumorigenesis taking place in the patient. The luteinizing hormone (LH) is a pituitary analog of HCG and is secreted in the pituitary gland of both males as well as females. Owing to its similarity to LH, this chorionic gonadotropin is clinically used to induce testosterone production in the testes of males and ovulation in the ovaries of females. It is also known to activate apoptosis and play an active role in cellular differentiation and proliferation.

Benefits of HCG:

  • A highly known benefit of HCG is that when combined with a low calorie diet, it triggers the hypothalamus to release upto 2000 to 4000 calories in a single day.
  • HCG when ingested orally is known to target the abnormal fat stored in the body. This fat mainly complies with lipids which do not burn even by dieting and rigorous workouts.
  • HCG intake greatly changes the appetite of a person. From large quantities ingested in a single meal, HCG administration naturally makes the person to eat smaller meals and this habit tends to stay with the person for life.
  • When taken orally, HCG initiates the body to lose some great amount of body fat as well as weight. The body will undergo contouring and one might see a decrease in its circumference until it adjusts itself to its metabolic weight.
  • As the person loses fat, his/her skin retracts improving the tenderness of the skin.
  • A major drawback associated with drugs used for weight loss is that low calorie in the body often leads to loss of muscle mass as well. However, in case of HCG there is no such side effect seen.

Users of HCG have also reported many beauty benefits of its use:

  • They have found that because of healthy eating their acne as well as black spots have greatly reduced.
  • People have experienced elimination of dark circles under the eyes as under HCG diet, fast food and sodas are not consumed which are the main causes of dark circles.

Beneficial in bodybuilding:

  • HCG happens to be one of the most desirable drugs for bodybuilders and people undergoing heavy workouts competitive purposes, for it helps in recovery of muscle soreness way much faster than other steroids.
  • Weight loss caused by HCG administration is rapid but is considered to be safe which is 20 to 40 pounds a month.

Human chorionic gonadotropin is largely employed as a tumor marker, as its β subunit is released by some cancerous cells. Therefore it is used for tracking seminoma, choriocarcinoma, germ cell tumors, hydatidiform mole formation and teratoma.

In order to experience long term benefits of HCG, it is important for the person to maintain the HCG diet as well as regular exercise regime.

Tuesday 24, Jan 2012

  IGF-1

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Somatomedin C is a protein found in humans and is commonly termed as Insulin-like growth factor 1 (IGF-1).  It is one of the most important hormones responsible for growth in children and has a molecular structure and size similar to that of Insulin.  It has a molecular weight of 7649 daltons and consists of a peptide chain with 70 amino acids in a single chain having three intramolecular disulphide bridges.

It is associated with the peptide family, commonly identified as the growth factors. Known to be a highly anabolic hormone, it is produced in liver and the peripheral tissues particularly in the cells of skeletal muscles. The presence of the Human Growth Hormone (HGH) in the body is considered to trigger the release of IGF-1 as its response. It is one of the most sought after substances by bodybuilders for the reason that it initiates the development of muscles in a very short period. As a result of rigorous training, the body experiences an increase in the Growth Hormone (GH) as well as the IGF-1 which causes the muscle cells to grow. Where GH is considered to have very strong anabolic properties, it is IGF which is believed to be responsible for its primary anabolic nature.

Growth hormone is mainly produced in the anterior pituitary gland which then flows into the blood stream stimulating the liver to produce IGF-1.  As a result, IGF-1  then  leads to the systemic body growth  of all the cells in the body mainly those of the  skeletal muscles, cartilage, bone, liver, kidney, nerves, skin, hematopoietic cell and the lungs. Apart from IFG’s insulin-like effects, IGF-1 also initiates regulated cell growth and development in the nerve cells and cellular DNA synthesis.

Deficiency of any of these two substances causes stunted growth in children who are then given recombinant GH to restore their condition.  People suffering from IGF-1 often suffer from Laron syndrome (Laron’s dwarfism) and are treated with recombinant IGF-1.

Normally 98% of IGF-1 is always seen to be bound to one of 6 binding proteins (IGF-BP).  The protein responsible for 80% binding of IGF is IGFBP-3and is bound to it in 1:1 molar ratio.

When administered, IGF-1 leads to the building of new muscle tissue by initiating the synthesis of protein along with the retention of nitrogen in the body. The prime functions associated with this are hyperplasia, which causes an increase in the muscle tissue and mitogenesis or the growth of new muscle fibers. This makes IGF -1 a highly favoured option for bodybuilders and power lifters seeking not only their muscle development but growth of muscle fibers as well.

Another benefit of employing IGF-1 is that it has a strong effect on the lipid metabolism of the body. In other words, it also plays a significant role in burning the body fat at a relatively fast rate. IFG-1 is also known to be a neuroprotector as well as a neuropromotor and finds its use in the improvement of functions related to the mind like reflexes, memory and ability to learn.

IGF-1 is employed as one of the most important substances required for the production of connective tissue in the joints, thereby ensuring appropriate bone density.

Being a highly potent drug for the development of muscle mass and fat-cutting, IGF’s Lr3 IGF-1 version is also considered to be equally powerful. Here Lr3IGF-1 stands for Long R3 Insulin-like Growth Factor-I or Long R3IGF-I.  It is a peptide of 83 amino acid analog of human IGF-I consisting of an entire human IGF-1 sequence. However, the only difference is that there is a substitution of an Arg for the Glu at position 3 and 13 amino acid extension at the N-terminus of the peptide.  It is for this reason that Long R3IGF-I is comparatively considered to be a more potent drug.

Some factors believed to cause changes in the levels of growth hormone (GH) and IGF-1 are the user genetic make-up, time of the day it is taken, age, sex, exercise status, stress level, nutrition level and body mass index (BMI). Reduction in IGF-1 signaling is also associated with the contribution of ‘anti-aging’ effects during calorie restriction phase.

A word of caution here is that increased use of IGF is often associated with enhanced risk of cancer.

Thursday 03, Nov 2011

  Inquiry launched into steroid dealing

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An inquiry has been launched by detectives into steroid-dealing after the death of a 23-year-old.

Police believe Lewis Allan, who died recently after falling ill at home in Eastbourne, used anabolic steroids over the last year.

From Theargus.co.uk:

Mr Allan was taken ill at his home in Bridgemere Road, Eastbourne, at about 2am on Monday.

He was taken to Eastbourne District General Hospital but was pronounced dead shortly after 3.30am.

Sussex Police are investigating his use of anabolic steroids – a prescription drug sometimes used by bodybuilders.

Possession or importation of the drug for personal use is legal, but supplying it is illegal.

A man has been arrested on suspicion of supplying drugs.

Tuesday 18, Oct 2011

  Kansas business owner indicted in steroid case

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Federal prosecutors alleged in an indictment that a Kansas business owner and a Maryland doctor illegally distributed more than $1.3 million worth of anabolic steroids.

According to court records, Baltazar, who allegedly wrote the prescriptions, did not see the patients in person.

From Kansascity.com:

Scott Lofquist, 51, of Fairway, and Rodney Baltazar, 48, of Elkton, Md., conspired to distribute 1.3 million units of steroids through Lifetime Wellness, Lofquist’s business, between 2008 and 2010, the indictment alleges.

Lofquist operated the business out of his home and from the home of another person in Kansas City, according to court records.

He allegedly sold the drugs to those trying to reverse the course of aging and to bodybuilders and athletes seeking to improve their performance.

Prosecutors are asking a judge to order the men to forfeit $1.36 million in proceeds from the alleged scheme.

Wednesday 31, Aug 2011

  Kidney damage possible in steroid-influenced bodybuilding

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Kidney damage possible in steroid-influenced bodybuildingAthletes using anabolic steroids for gaining muscle mass and strength could end up destroying their kidney function.

The finding was disclosed in a paper being presented at the American Society of Nephrology‘s 42nd Annual Meeting and Scientific Exposition in San Diego, CA.

From Sciencedaily.com:

Reports of professional athletes who abuse anabolic steroids are increasingly common. Most people know that using steroids is not good for your health, but until now, their effects on the kidneys have not been known. Leal Herlitz, MD (Columbia University Medical Center) and her colleagues recently conducted the first study describing injury to the kidneys following long-term abuse of anabolic steroids. The investigators studied a group of 10 bodybuilders who used steroids for many years and developed protein leakage into the urine and severe reductions in kidney function. Kidney tests revealed that nine of the ten bodybuilders developed a condition called focal segmental glomerulosclerosis, a type of scarring within the kidneys. This disease typically occurs when the kidneys are overworked. The kidney damage in the bodybuilders has similarities to that seen in morbidly obese patients, but appears to be even more severe.

It was also suggested that habitual use of steroids has serious harmful effects on the kidneys that were not previously recognized.

Friday 15, Jul 2011

  Suspected steroid ring busted by authorities

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Suspected steroid ring busted by authoritiesA suspected steroid ring in Florida that was accused of distributing anti-aging treatments to celebrities and muscle building drugs to professional athletes has been busted by authorities.

At least eight people were arrested in Florida, New York, and Texas, according to officials.

From Reuters.com:

“There are celebrities involved in the case as consumers,” Albany District Attorney David Soares told reporters in Orlando.

Officials also confirmed a report in Albany Times Union that the investigation could expose steroid use by current and former Major League Baseball players, National Football League players, bodybuilders and college and high school athletes.

Soares alleges the network prescribed anabolic steroids, human growth hormone and other substances over the Internet and without face-to-face examinations, supplying a large portion of the national market for illegal online steroid sales.

“The recent steroid raid in Florida doesn’t surprise me at all. People from all walks of life now are using performance enhancing substances,” Victor Conte, the head of the BALCO lab who served jail time on steroid distribution charges, told Reuters. “From athletes to movie stars, there seems to be an ever-growing need to find a competitive edge.”

Thursday 17, Feb 2011

  Police officer arrested in anabolic steroids supply investigation

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Police officer arrested in anabolic steroids supply investigationA 26-year-old Metropolitan police constable was recently arrested by detectives investigating a body building drug supply racket.

The police officer was held after a series of early morning raids in Swansea, South Wales.

From Guardian.co.uk:

A Metropolitan police spokesman said the men are believed to be linked to a network supplying steroids to hundreds of people across South Wales.

He said: “Officers are expected to meet the highest standards of honesty and integrity. The Met is determined that those who fail to meet these standards will be dealt with swiftly and robustly.”

The operation was carried out by members of Scotland Yard’s directorate of professional standards with officers from South Wales police’s anti-corruption team.

Officers suspect the men were supplying anabolic steroids in pill and injectable forms to bodybuilders and weight trainers.

Some sportsmen claim steroids help them train harder, build muscle mass and recover from exercise more quickly.

Steroids are categorised as class C drugs and can only be sold by pharmacists with a doctor’s prescription.

The officer was arrested on suspicion of supplying controlled class C drugs following an investigation by anti-corruption officers.

Wednesday 29, Dec 2010

  Arnold Schwarzenegger lights up Olympics

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Arnold Schwarzenegger lights up OlympicsArnold Schwarzenegger, the governor of California and former bodybuilding great, recently had his way during the torch exchange of the 2010 Games.

Schwarzenegger was invited by Sebastian Coe to the London Games. Coe demonstrated diplomatic behavior when asked if the former Mr Olympia will be the torch bearer.

From Guardian.co.uk:

Serving politicians are seldom granted the honour; nor are former bodybuilders with a history of steroid use. Schwarzenegger may have won the Mr Olympia title seven times but the Olympics run to a rather different set of rules.

Nonetheless celebrity counts for something and, at an occasion which has fashioned itself as the “green” Games, so does a strong record on green issues during his term as governor of California – a record cited by John Furlong, the head of Vanoc, the Games’ organisers, in defending the invitation. “He has taken an extraordinary position on the environment and has developed a great relationship with the province of British Columbia,” he said.

Certainly it proved to be a hugely popular decision with the Vancouver public, whose enthusiasm for the Olympics, and desire for the 2010 Games to be seen around the world as a success, seems to be building with every passing hour.

Shelley Rudman, Britain’s only medalist from the Turin Winter Games four years ago, was the only undisputed choice and was selected at a team reception in downtown Vancouver.

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