10/12/2019 6:58 pm Welcome to isteroids.com - BLOG

Tuesday 01, Nov 2011

  Teriparatide Becomes Preferred Drug for Steroid-Induced Osteoporosis

Posted By
Pin it Share on Tumblr

Teriparatide, the anabolic agent, has received a boost in status as a preferentially effective treatment for glucocorticoid-induced osteoporosis in the form of a second, confirmatory, randomized double-blind trial.

The trial demonstrated that the drug achieves substantially greater increases in bone mineral density compared to a bisphosphonate.

These positive study findings are bolstered by a biologically plausible mechanism of benefit, according to the observations of Dr. Kenneth G. Saag at the annual meeting of the American Society for Bone and Mineral Research.

Monday 07, Feb 2011

  Bone loss may happen with antiretroviral medications

Posted By
Pin it Share on Tumblr

Bone loss may happen with antiretroviral medicationsAntiretroviral medications may be adding to that risk of bone loss in individuals with HIV infection when compared to people without HIV.

Results of two small but well-conducted studies demonstrated the emphasis towards concern about the differential effects of antiretrovirals on BMD (bone mineral density), as per Dr. Dolores Shoback.

“I think it’s very provocative. We certainly need more data, and this needs to be confirmed,” Dr. Shoback said at a meeting, which was sponsored by the University of California, San Francisco.

Friday 12, Nov 2010

  Steroid-Induced Osteoporosis gets better treated with Teriparatide

Posted By
Pin it Share on Tumblr

steroid-induced-osteoporosis-gets-better-treated-with-teriparatideA recent study has determined that glucocorticoid-induced osteoporosis (OP) is now treatable with a synthetic form of the human parathyroid hormone, Teriparatide.

It was found by the researchers that patients with glucocorticoid-induced OP and administered with teriparatide for 36 months had a greater increase in bone mineral density (BMD) and fewer new vertebral fractures than those treated with alendronate.

The findings of this study are published in the November issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR).

Sunday 01, Aug 2010

  Steroid-induced osteoporosis is better treated with Teriparatide

Posted By
Pin it Share on Tumblr

Steroid-induced osteoporosis is better treated with TeriparatideForteo or injectable Teriparatide is superior to Fosamax or oral Alendronate, in a head-to-head comparison, for increasing the level of bone mineral density (BMD) by as much as two times, according to investigators.

It was remarked by Philip N. Sambrook, M.D., of the University of Sydney that teriparatide could be considered as a first-line therapy for treating osteoporosis induced by steroids.

Kenneth Saag, M.D., of the University of Alabama at Birmingham and his colleagues said that considerable BMD improvements in the spine and hip regions are possible with Teriparatide.

Tuesday 06, Apr 2010

  Teriparatide superior to Alendronate for treating Osteoporosis

Posted By
Pin it Share on Tumblr

The injectable form of Teriparatide, Forteo, is superior to oral Alendronate, Fosamax, in a head-to-head comparison when it comes to improving bone mineral density (BMD) by as much as twice.

Teriparatide promotes greater increases in bone-mineral density at the spine and hip, as per Kenneth Saag, M.D., of the University of Alabama at Birmingham and his colleagues.Teriparatide superior to Alendronate for treating Osteoporosis

Philip N. Sambrook, M.D., of the University of Sydney, said that Saag’s findings suggest that teriparatide is a superior drug for treating steroid-induced Osteoporosis.

Thursday 24, Dec 2009

  Adiponectin, the metabolic link between bone mineral density and obesity

Posted By
Pin it Share on Tumblr

Adiponectin, the metabolic link between bone mineral density and obesityAdiponectin, a protein secreted from adipocytes, has been found to be the metabolic link that can explain, in part, about the positive relationship between obesity and both minimized susceptibility to fractures and bone mineral density, as per researchers at the University of Toronto, Faculty of Medicine, Toronto, Canada.

This study appeared in an issue of Experimental Biology and Medicine.

Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine, said that these intriguing results provide noteworthy insights into adiponectin secretion, from adipocytes, loss of bone mineral density, and resulting increased fractures.

Wednesday 02, Dec 2009

  Steroid-induced osteoporosis can be effectively treated with Teriparatide

Posted By
Pin it Share on Tumblr

Steroid-induced osteoporosis can be effectively treated with TeriparatideAccording to a recent study, glucocorticoid-induced osteoporosis (OP) can be effectively treated with a synthetic form of the human parathyroid hormone, Teriparatide. It was found by the involved researchers that patients with glucocorticoid-induced OP and treated with teriparatide for a period of 36 months had a greater increase in BMD (bone mineral density) and experienced fewer new vertebral fractures than patients being treated with alendronate.

The study findings were published in the November issue of Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR).

Kenneth Saag, M.D., from the University of Alabama, remarked that the need of therapies for mitigating the side-effects of steroid use and improving bone mass on a substantial manner is vital.

Friday 30, Oct 2009

  Teriparatide effective than Alendronate for steroid-induced osteoporosis

Posted By
Pin it Share on Tumblr

Teriparatide effective than Alendronate for steroid-induced osteoporosisInjectable teriparatide (foreto) increases BMD (bone mineral density) by as much as two percent when compared to oral alendronate (fosamax) in a head-to-head comparison, according to a recent study.

It was remarked by Kenneth Saag, M.D., of the University of Alabama at Birmingham and his colleagues, that teriparatide was found in a relationship with enhanced improvements in the level of bone mineral density at the spine and hip.

Philip N. Sambrook, M.D., of the University of Sydney, said that teriparatide can prove to be a breakthrough option as a potential first-line therapy for steroid-Induced Osteoporosis as per the findings of Saag and his colleagues.

For informational purposes, teriparatide is currently approved for men and postmenopausal women with osteoporosis suffering from the high risk of fractures.

Tuesday 28, Jul 2009

  Soccer improves the health standards of growing boys

Posted By
Pin it Share on Tumblr

Soccer improves the health standards of growing boysAccording to a new research published by the American College of Sports Medicine (ACSM), long-term and regular participation in soccer greatly improves the health profile of young boys.

The study revealed sharp contrasts between regular and long-term benefits from extracurricular sports participation against physical education alone.

Soccer needs to be promoted as a low-cost option to facilitate sound and healthy growth of growing boys as per lead researcher Jose A. L. Calbet, M.D., Ph.D., of the University of Las Palmas de Gran Canaria in Spain.

It was revealed that growing boys who play soccer not just benefit from increased whole body bone mineral density but they also witness high regional measurements in areas such as femoral neck in the hip and lumbar spine.

Tuesday 28, Jul 2009

  Sex steroid hormones affect bone density in men

Posted By
Pin it Share on Tumblr

Sex steroid hormones affect bone density in menA study conducted by Dr. Channing J. Paller and associates of Johns Hopkins School of Medicine in Baltimore showed that lower serum levels of free estradiol and free testosterone and higher sex hormone – binding globulin (SHBG) concentrations are associated with low bone mineral density (BMD) in adult men. Sex steroid hormones have long been established to have an influence in the bone mineral density of older women, but are less well-studied in men.

The study involved 1,185 adult male participants in the Third National Health and Nutrition Examination Survey (NHANES III).

The researchers identified “consistent relationships” between low free estradiol, low free testosterone and high sex hormone – binding globulin with osteopenia.

Osteopenia is defined as a condition where bone mineral density is lower than normal. It has a BMD score of -1 to -2.5. It is considered by doctors as a precursor to osteoporosis, alhtough not all osteopenic patients will develop osteoporosis later on in life.

Lower levels of sex hormone – binding globulin appeared to also lower the incidence of osteopenia. The researchers concluded that future studies should consider the alteration of clinical management to screen for osteopenia in men of all ages who have low hormone levels, but do not necessarily meet the definition of hypogonadism.

According to Medscape:

These results “call for prospective studies looking at BMD and/or fracture risk in association with hormone levels,” Dr. Paller and colleagues conclude. “In particular, future studies should explore the question of altering clinical management to screen for osteopenia in men of all ages who have low hormone levels, but do not meet the clinical definition of hypogonadism.”

Next »