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Thursday 25, Mar 2010

  Death risk high with use of anti-inflammatory steroids

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death-risk-high-with-use-of-anti-inflammatory-steroidsThe risk of death is higher when anti-inflammatory steroids are used for traumatic head injuries, according to a review of studies about the treatment.

This review was published by the British-based Cochrane Library and draws heavily from a recently concluded study of corticosteroid treatment for brain injury that included 10,008 patients, more than all similar studies combined.

Dr. Phil Alderson, lead author of the Cochrane study, said not all physicians routinely prescribe corticosteroids but usage is quite widespread.

Saturday 13, Feb 2010

  Brain injury treatable with optimization of Progesterone

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Brain injury treatable with optimization of ProgesteroneProgesterone is under testing stage by researchers aiming to optimize the effectiveness of this hormone to treat patients suffering from traumatic brain injury.

Two abstracts highlighting Emory research on the hormone were presented at the 2009 Society for Neuroscience (SFN) meeting in Chicago.

This trial was developed by Donald Stein, PhD, Asa G. Candler Professor of Emergency Medicine at Emory School of Medicine.

The study authors noted that a low amount of Vitamin D can boost ability of progesterone to protect neurons from excito-toxicity, which is a principal cause of brain injury and cell death.

Friday 29, Jan 2010

  Progesterone optimized for treating brain injury

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progesterone-optimized-for-treating-brain-injuryResearchers are moving ahead by testing progesterone in the quest to optimizing the effectiveness of the hormone for treating traumatic brain injury.

In this direction, two abstracts summarizing Emory research on the hormone were presented at the 2009 Society for Neuroscience (SFN) meeting in Chicago.

A multisite phase III clinical trial called ProTECT III will be initiated for examining the effectiveness of the hormone in the coming few months. The trial was developed by Donald Stein, PhD, Asa G. Candler Professor of Emergency Medicine at Emory School of Medicine.

It was noted by the authors that a low amount of Vitamin D has the ability to boost progesterone’s ability to guard neurons from excito-toxicity, which is a principal cause of brain injury and cell death.