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Sunday 07, Feb 2010

  Benefits of Avastin effective in delaying brain tumor progression

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Benefits of Avastin effective in delaying brain tumor progressionAs per a retrospective study of 22 patients conducted by a researcher at the Seattle Cancer Care Alliance, the usage of Avastin alone is safe as well as effective for delaying progression of brain tumor when it comes to treating a subgroup of recurrent Grade 3 brain tumors.

Avastin, known generically as bevacizumab, is the first-ever approved therapy for inhibiting angiogenesis.

Angiogenesis is the process by which new blood vessels are developed and transport vital nutrients to a tumor. It is important to note here that Avastin is approved for treating certain metastatic colon cancers and non-small cell lung cancer.

Marc Chamberlain, M.D., author of the study and director of the Neuro-oncology Program at the SCCA and a professor of neurology and neurological surgery at the University Of Washington School Of Medicine, said that Bevacizumab is an important drug of all of the targeted therapies for gliomas.

Tuesday 06, Oct 2009

  Angiogenesis inhibitor reduces edema to improve glioblastoma survival

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Angiogenesis inhibitor reduces edema to improve glioblastoma survivalAccording to a recently concluded study by researchers from the Massachusetts General Hospital, the positive effects of anti-angiogenesis drugs for treating the deadly brain tumor known as glioblastomas gives an impression of originating primarily from edema reduction and not from any direct anti-tumor effect.

The findings of this study suggest that antiangiogenesis therapy can enhance patient survival even in circumstances revolving cases of persistent tumor growth, according to Rakesh K. Jain, PhD, director of the Steele Laboratory in the MGH Department of Radiation Oncology, the study’s co-senior author.

This study is expected to offer a new paradigm to help physicians treating their patients with deadly brain tumors.