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Tuesday 29, Sep 2009

  Testosterone deficiency linked to increased mortality in men

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Testosterone deficiency linked to increased mortality in menAccording to as study conducted by the Boston University School of Medicine (BUSM) researchers, deficiencies in androgen hormones, particularly testosterone may be linked increased incidence of cardiovascular disease in men. However, it is alleged to increase the risk of prostate cancer in men.

In the Journal of Andrology, several studies were published linking steroid hormones deficiency to increased mortality in men.

BUSM researchers, in collaboration with researchers from Lahey Clinic Northshore, Peabody, Massachusetts, evaluated several of the published studies linking androgen deficiencies with cardiovascular disease. They have determined that a relationship indeed exist between the two factors.

According to lead author Dr. Abdulmaged M. Traish, professor of biochemistry and urology and director of Laboratories for Sexual Medicine, Institute for Sexual Medicine at BUSM, androgen replacement therapy could be a potential treatment to reduce risk for cardiovascular disease in men. It should be carefully monitored, however, to detect any signs of prostate diseases in men.

Furthermore, the researchers recommend large, long-term, double blind, randomized, placebo controlled clinical trials be performed in order to establish the role of androgen deficiency in increasing the risk of cardiovascular disease in men.

Traish added that these initial findings suggest further studies to be conducted regarding the role of androgens in preventing cardiovascular disease in men.

Friday 05, Jun 2009

  High Dose Of Steroids Linked To Cardiovascular Disease

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High Dose Of Steroids Linked To Cardiovascular DiseasePatients who used high-dose steroids had 2.5-times the risk of developing cardiovascular disease overall than patients who did not use high doses of steroids. This was the assumption of the researchers (as per the Annals of Internal Medicine)when they evaluated the health records of 68,781 people who used steroids between 1993 and 1996.

The patients who were evaluated were also tracked for one to five years. Researchers pointed out that high steroid use happens when patients use more than 7.5milligram of oral, inhaled, topical and nasal steroids every day.

Patients are prescribed with steroid to treat diseases such as asthma, joints disorders, digestive tract problems, psoriasis and some form of arthritis because of its anti-inflammatory property. Although the study did not directly identify steroid as one of the causes, researchers claim that the connection is strong enough to consider the potential risk of heart conditions with high steroid use.