Inhaled corticosteroids may have a significantly decreased mortality risk when used by patients with chronic obstructive pulmonary disease (COPD). Studies reported by journal of the American College of Chest Physicians (ACCP), found that relief is granted to patients who receive inhaled corticosteroids within 30 days of hospital discharge. These patients tend to have a 25 percent reduced all-cause mortality rate as per findings of this study.

In the steroid therapy, steroids were paired with beta-agonists to treat chronic obstructive pulmonary disease (COPD) to reduce Cardiovascular-related death rate by 38 percent.

From bio science:

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Dr. Macie and colleagues found that the mortality rates in patients 65+ who received inhaled corticosteroids were 11.7 percent, compared with 13.1 percent for those who did not. Patients in the younger group showed even greater results, with a mortality rate of 3.0 percent for patients receiving inhaled corticosteroids within 90 days, compared with 6.0 percent for those who did not, providing a mortality reduction rate of 53 percent. When patients who received steroids in the year prior were removed from the analysis, mortality was reduced by 34 percent. Researchers attribute this finding to multifactorial reasons, including reductions in exacerbations of the disease and suppression of inflammation.

This therapy showed effects on the basis of ages of patients suffering from COPD. Studies showed mortality rates in patients above 65 years of age who received inhaled corticosteroids were 11.7 percent better as compared with 13.1 percent for those who were not administered with corticosteroids. Patients in the younger group showed even greater results, with a mortality rate of 3.0 percent for patients receiving inhaled corticosteroids within 90 days.

There was also a decrease in the death rate of patients who were given corticosteroids by as much as 23 % as compared to those who were on inhaled steroids along with bronchodilators. The study revealed that there was a potential to cure COPD at a faster rate when corticosteroids is given. However, this steroid therapy needs to be prescribed as COPD after diagnosis to get better results.

Tags: beta-agonists, bronchodilators, cardiovascular, chronic obstructive pulmonary disease (COPD), corticosteroids

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Medical advances have once again hailed good news, this time for the asthmatic patients. It says that older women suffering from asthma inhaling steroids are comparatively less prone to die from other ailments over five years as compared to those not doing so. Where it does say that inhaling corticosteroids do help women in combating other ailments, it does not guarantee that this might work against cancer and similar cases.

The good news indeed is that the intake of these steroids immensely reduces the risk of diseases developing due to cardiovascular malfunctions. The report was released by first taking into account 2,671 women suffering from persistent asthma. The ones found healthier than the rest showed that they were taking inhaled steroids.

From NDTV Doctor:

Therapy with inhaled corticosteroids (ICSs) decreases the risk of asthma exacerbations. Recent studies have suggested that ICS therapy also may decrease the risk of cardiovascular disease, and perhaps of all-cause mortality. To examine this hypothesis in a large, well-characterised cohort of asthmatic women, researchers from America studied 2,671 women with persistent asthma. The participants were asked to complete supplementary asthma questionnaire. Fifty-four percent of these women reported inhaled steroid use.

Over the next five years, it was found that 87 women (3.3 percent) died. Twenty-two women died of cardiovascular causes, 31 from cancer, and 34 died from other causes (including 4 from asthma). The use of inhaled steroid therapy at the outset, relative to non-use, was found to be associated with a significant 42 percent reduced likelihood of dying from any cause and a 65 percent reduced likelihood of dying from a heart-related cause. However, using inhaled steroids did not significantly cut the risk of dying from cancer or other causes.

Thus we see that early dosages of inhaled steroid therapy may prove to be greatly beneficial for cases beyond improved asthma control as well. This further adds and supports the results of two recently done studies from Canada, which mention that steroids administered in inhaled form can have great benefits outside the lungs.

Thus baring some cases of cancer, we see that inhaled steroids have proved to be highly beneficial of asthma patients. This is so because results clearly reveal that around 42 percent of asthma patients showed immunity against any cause and 65 percent particularly against cardio vascular ailments.

Tags: Asthma, asthmatics, cardiovascular, corticosteroids, Inhaled steroids, lungs, steroids

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