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Thursday 25, Nov 2010

  COPD management with steroids leads to reduced mortality rate

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COPD management with steroids leads to reduced mortality rateSignificant reductions in mortality rate can be noticed in COPD (chronic obstructive pulmonary disease) patients when inhaled corticosteroids are used.

This finding was disclosed by a study appearing in an issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP).

It was reported by this study that individuals making use of steroids paired with beta-agonists demonstrated a fall in cardiovascular-related death alone by 38 percent.

Friday 20, Aug 2010

  Reduced mortality rate seen with steroids for COPD management

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Reduced mortality rate seen with steroids for COPD managementAccording to a study appearing in an issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians (ACCP), mortality rate can be significantly reduced in COPD (chronic obstructive pulmonary disease) patients when inhaled corticosteroids are used.

The study reported that patients making use of steroids paired with beta-agonists experienced a fall in cardiovascular-related death alone by 38 percent.

W. Michael Alberts, MD, FCCP, President of the ACCP, said the study findings are intriguing for clinicians and suggest the need of future research for defining the roles and mechanisms of the effect of inhaled steroids on both cardiovascular and respiratory mortality.

Friday 30, Jul 2010

  COPD patients could benefit with steroids

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COPD patients could benefit with steroidsReduced mortality risk can be noticed in patients afflicted with chronic obstructive pulmonary disease (COPD) when they are treated with inhaled steroids.

It was remarked by Christine Macie, MD, FCCP, Cambridge Hospital, Ontario, Canada and author of the study that patients on steroids are relatively better protected than those not making use of them.

Dr. Macie also remarked that inhaled corticosteroids could be highly effective to prolong lives of patients with COPD.

Tuesday 27, Jul 2010

  Johns Hopkins experts made call for extra caution

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Johns Hopkins experts made call for extra cautionAccording to Lung disease experts at Johns Hopkins, physicians treating their patients afflicted with COPD (chronic obstructive pulmonary disease) need to observe extra caution while dealing with them.

It was remarked by lead author and pulmonologist M. Brad Drummond, M.D., M.H.S. that this finding has implications and serves a reminder to COPD patients so that they could take necessary preventive steps for avoiding pneumonia, which doubles their risk of death.

As many as 11 million Americans are afflicted with COPD every year and a big majority of this population belongs to the category of past or present-day smokers.

Monday 26, Jul 2010

  Treatment involving inhaled steroids useful for COPD management

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Treatment involving inhaled steroids useful for COPD managementChronic obstructive pulmonary disease (COPD), which is one of the five leading causes of death worldwide, is characterized by an inflammatory response to inhaled fumes such as tobacco smoke that results in breath shortness, limited airflow, and loss of lung function.

Fluticasone propionate, which is an inhaled steroid, could minimize the ability of major pathogens for invading the respiratory epithelium, as per a study by Sebastian Albertí (Institut Universitari d’Investigacions en Ciències de la Salut, IUNICS, Palma de Mallorca, Spain) and colleagues.

Findings of the study are expected to provide implications to physicians all over the world when it comes to treating COPD patients.

Sunday 18, Jul 2010

  Inhaled steroids effective for treating COPD

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COPD treatment is facilitated with inhaled steroidsPatients afflicted with chronic obstructive pulmonary disease or COPD can be effectively treated and experienced reduced mortality risk when treated with inhaled corticosteroids, as per a study appearing in the CHEST, which is a peer-reviewed journal of the American College of Chest Physicians (ACCP).

COPD patients who make use of inhaled corticosteroids benefit from improved survival rates as per Christine Macie, MD, FCCP, Cambridge Hospital, Ontario, Canada and author of this study.

COPD patients administered with inhaled steroids are relatively in a better position than those not using it, as per Dr. Macie. It was also revealed in the study that cardiovascular related deaths were reduced by as much as 38% and a 25% reduced all-cause mortality rate was noticed among patients administered with inhaled corticosteroids within thirty days of discharge from the hospital.

Friday 25, Jun 2010

  Inhaled corticosteroids helpful for COPD patients

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Inhaled corticosteroids helpful for COPD patientsReduced mortality risk is experienced in patients with COPD (Chronic obstructive pulmonary disease) who are administered with inhaled corticosteroids. This finding was disclosed in a study published in the CHEST, peer-reviewed journal of the American College of Chest Physicians (ACCP).

It was said by Christine Macie, MD, FCCP, Cambridge Hospital, Ontario, Canada and author of the study that inhaled corticosteroids are effective in prolonging lives of patients with COPD.

COPD patients who are using inhaled corticosteroids are relatively better protected than those not making use of them, as per Dr. Macie.

Tuesday 08, Jun 2010

  Macrolide antibiotic use can minimize COPD exacerbations

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Macrolide antibiotic use can minimize COPD exacerbationsAccording to a London-based study, frequency of exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) can be reduced by almost 35 percent with the use of a macrolide antibiotic in the long term.

It was remarked by lead author of the paper, Terence A. R. Seemungal, Ph.D., and Jadwiga Wedzicha, M.D., principle investigator that the study results suggest that there is a significant effect of low-dose macrolide therapy on the frequency of exacerbation, and severity with moderate to severe COPD.

From News-Medical.Net:

While their findings are encouraging, Dr. Seemungal points out that they must be put in context with future findings. Furthermore, the threat of growing antibiotic resistance resulting from widespread prophylactic use of erythromycin is not a trivial concern. “In this scenario, substantial, widespread emergence of macrolide bacterial resistance is virtually foreordained, with attendant reduction in the antimicrobial usefulness of this drug class,” wrote Ken M. Kunisaki, M.D. and Denise E. Niewoehner, M.D., of the Veterans Affairs Medical Center in Minneapolis, in the accompanying editorial. “Balancing benefit against harm could pose a dilemma for which there might be no clear answers.”

Moreover, not all of the study patients were treated with guideline-recommended therapy, such as inhaled corticosteroids or inhaled long-acting bronchodilators, which have been shown to decrease exacerbation frequency. The degree of added benefit of erythromycin over and above standard therapy will require further study.

“Observations that any intervention might decrease the frequency and severity of acute exacerbations in COPD present considerable public health implications,” observed John Heffner, M.D., past president of the ATS. “Exacerbations occur about once a year among patients with moderate to severe COPD and account for more than $30 billion dollars in direct and indirect costs annually in the United States alone.”

The study results were published in the first issue for December of the American Journal of Respiratory and Critical Care Medicine, which is published by the American Thoracic Society.

Sunday 16, May 2010

  COPD patients using inhaled steroids at risk for severe pneumonia

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COPD patients using inhaled steroids at risk for severe pneumoniaMedical practitioners generally recommend inhaled steroids to patients affected by Chronic Obstructive Pulmonary Disease (COPD) but a study has found out that these anti-inflammatory drugs could increase the risk of pneumonia.

It was remarked by the researchers that present inhaled corticosteroid use was linked with a significant 70 percent increase in the risk of being hospitalization for pneumonia. This remark came after evaluating a large cohort of patients with COPD.

These findings were reported in the second issue of the July American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Saturday 24, Apr 2010

  Risk of pneumonia can increase dramatically with inhaled corticosteroids

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Risk of pneumonia can increase dramatically with inhaled corticosteroidsA great sense of caution has been recommended by lung disease experts at John Hopkins when it comes to prescribing inhaled corticosteroid drugs to patients with chronic obstructive pulmonary disease (COPD).

This caution call was made after evidence was found suggesting that a widely used anti-inflammatory medication increases the risk of pneumonia by a full third.

It was remarked by the researchers that it is not clear why the corticosteroid treatment increases the risk but it is suspected that it is because corticosteroids suppress the immune system.

Pulmonologist M. Brad Drummond, M.D., M.H.S., led the study and was supported by Eddy Fan, M.D.; other researchers involved in this study, conducted solely at Hopkins, were Elliott Dasenbrook, M.D., M.H.S.; Marshall Pitz, M.D., M.H.S., now at the University of Manitoba, in Winnipeg, Canada; and David Murphy, M.D.

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