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Saturday 15, May 2010

  Brain damage can be curbed by blood pressure drug

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Brain damage can be curbed by blood pressure drugPrazosin, a drug used to treat high blood pressure and enlargement of the prostate, could protect the brain from damage caused by Alzheimer’s disease, post-traumatic stress disorder, depression and schizophrenia.

The drug, which is also prescribed as an antipsychotic medication, tends to block the increase of steroids hormones known to the world as glucocorticoids. This finding was disclosed by researchers at the Oregon Health & Science University and Portland Veterans Affairs Medical Center.

The study was funded by the U.S. Department of Veterans Affairs.

Friday 12, Mar 2010

  Need for volunteers in treatment resistant depression research

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Need for volunteers in treatment resistant depression researchResearchers at the University of Bristol are looking for volunteers to find out if hydrocortisone, a drug affecting stress system of the body, could help people with depression and not responding to present forms of treatment.

It is believed that Severe or recurrent depression affects 3-5 percent of the population and 10-30 percent of this population do not respond to the present-day treatment options.

Dr Andrea Malizia leading the team of Bristol researchers has a long-standing clinical and research interest in treatment resistant depression and spearheads a specialist outpatient service at the Bristol Royal Infirmary.

Wednesday 25, Feb 2009


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survey-suggests-other-indirect-side-effects-of-steroid-useA recent survey done on the use of anabolic steroids in the athletes of the National Football League revealed that the drugs are correlated with various injuries and medical problems later on in life. The survey was sent to 3,693 members of the NFL Retired Players Association and about 20.3% of the players from the 1980′s admitted to having used steroids during their careers. That time, it was still accepted to take steroids since testing for performance enhancing drugs in the NFL started only in 1987. Most of those who used steroids were offensive linemen and defensive linemen, and they also registered with the highest rate of injuries including problems with joint ligaments and cartilage.

While there is no information on the type, duration and dosage of steroids these athletes used, researchers claim the finding to be a “snowball effect”. This means that after the joint problems have occurred, other disease entities developed directly or indirectly due to the injuries. These include inactivity, osteoarthritis, depression, obesity and diabetes. Indeed, if you look at the natural history of these diseases, they are related to one another. Many respondents claimed that they have also suffered from these effects after they had been injured due to steroid use.