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Monday 26, Jul 2010

  Treatment involving inhaled steroids useful for COPD management

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Treatment involving inhaled steroids useful for COPD managementChronic obstructive pulmonary disease (COPD), which is one of the five leading causes of death worldwide, is characterized by an inflammatory response to inhaled fumes such as tobacco smoke that results in breath shortness, limited airflow, and loss of lung function.

Fluticasone propionate, which is an inhaled steroid, could minimize the ability of major pathogens for invading the respiratory epithelium, as per a study by Sebastian Albertí (Institut Universitari d’Investigacions en Ciències de la Salut, IUNICS, Palma de Mallorca, Spain) and colleagues.

Findings of the study are expected to provide implications to physicians all over the world when it comes to treating COPD patients.

Thursday 01, Jul 2010

  Hay fever patients could be treated with steroid nasal sprays

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Hay fever patients could be treated with steroid nasal spraysA research has suggested that fluticasone propionate (Flonase), a corticosteroid nasal spray, is superior to a combination of popular anti-allergy drugs loratidine (Claritin) and montelukast (Singulair) for managing seasonal allergies.

It was remarked by Robert Naclerio, M.D., professor of surgery at the University of Chicago and director of the study that inflammation measures were significantly better for patients afflicted with hay fever and treated with fluticasone propionate.

This finding by researchers from University of Chicago was presented at the 58th annual meeting of the American Academy of Allergy, Asthma and Immunology.

Thursday 08, Apr 2010

  Hay fever patients can expect relief with steroid nasal sprays

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Hay fever patients can expect relief with steroid nasal spraysFluticasone propionate (Flonase), the corticosteroid nasal spray, is effective in controlling seasonal allergies than a combination of two popular anti-allergy drugs: loratidine (Claritin) and montelukast (Singulair). This finding was disclosed by researchers from the University of Chicago.

This study was presented on March 4 at the 58th annual meeting of the American Academy of Allergy, Asthma and Immunology.

Robert Naclerio, M.D., professor of surgery at the University of Chicago and director of the study, said that symptom scores for patients on fluticasone were better than those on a combination of two popular anti-allergy drugs.

Tuesday 06, Apr 2010

  Corticosteroid Nasal spray useful for treating hay fever

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Corticosteroid Nasal spray useful for treating hay feverA corticosteroid nasal spray, fluticasone propionate (Flonase), was found to be an effective option for controlling seasonal allergies when compared to a combination of popular anti-allergy drugs loratidine (Claritin) and montelukast (Singulair), as per researchers from the University of Chicago.

The study was presented at the 58th annual meeting of the American Academy of Allergy, Asthma and Immunology.

Robert Naclerio, M.D., professor of surgery at the University of Chicago and director of the study, said that inflammation measures were significantly better for patients with hay fever taking fluticasone propionate. It was also said that fluticasone may be a better first choice for treating seasonal allergic rhinitis because of its benefits and low cost.

Friday 22, Jan 2010

  Patients suffering from mild, persistent asthma can now expect relief

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Patients suffering from mild, persistent asthma can now expect reliefAccording to a new research, individuals with mild and persistent asthma and administered with twice-daily use of inhaled steroids may make lesser use of inhalers or switch to a new pill.

Stephen P. Peters, M.D., Ph.D., lead author and a professor of pediatrics, internal medicine-pulmonary and associate director of the Center for Human Genomics, remarked that this finding is good news for patients with mild, persistent asthma as it gives them extra choices for asthma management.

Peters said that it would be best for patients faring well with the twice a day inhaled corticosteroid treatment option and seeking other options to talk to their doctors before making a decision.

 


Tuesday 25, Aug 2009

  Acute sinusitis can be prevented with steroids

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Acute sinusitis can be prevented with steroidsAccording to a new review by researchers from Israel, steroid nasal sprays – either alone or with antibiotic therapy – can prove to be effective in preventing and curing acute sinusitis, which can develop following a chest cold.

The review was published in an issue of The Cochrane Library, a renowned publication of The Cochrane Collaboration, which is an international organization evaluating all aspects of health care.

It is believed that approximately 37 million Americans suffer from acute sinusitis. The findings of this review will help them and patients worldwide to get relief.

From News-Medical.Net:

Study participants, who underwent X-rays or nasal endoscopy to confirm diagnosis, received either a placebo or intranasal corticosteroids for two or three weeks, alone or in combination with antibiotics. Intranasal corticosteroids used included fluticasone propionate (Flonase), mometasone furoate (Nasonex) and budesonide (Rhinocort).

Overall, 73 percent of the patients treated with nasal steroids experienced relief or marked improvement of symptoms during the study period, compared with only 66.4 percent of patients who received the placebo.

“For every 100 patients treated with intranasal corticosteroids, seven additional patients had complete or marked symptom relief,” compared to those in the placebo group, the reviewers found.

Researchers pooled data from three of the four studies, excluding the lowest-quality study from the statistical analysis.

None of the studies reported serious side effects, and rates of sinusitis relapse were similar between the treatment and placebo groups.

Stronger doses of nasal steroids appeared to work better. Patients receiving daily doses of 400 micrograms were more likely to experience relief of sinusitis symptoms, than were patients receiving 200-microgram doses.

Allen Seiden, M.D., director of the University of Cincinnati Taste and Smell Center, remarked that more data is required before recommendations for intranasal corticosteroids can be made.

The involved reviewers were of the view that the findings of this review support the clinical rationale behind addition of an intranasal corticosteroid to antibiotic therapy.

Friday 24, Jul 2009

  Everything you need to know about Flonase

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Everything you need to know about FlonaseFlonase nasal spray is a synthetic cortisosteroid that contains an active compononent called fluticasone propionate. Flonase is used to treat nasal conditions like sneezing, runny nose and congestion due to seasonal or year-round allergies. There are certain information that you need to know before using this product. Inform your doctor if you are taking antibiotics, antifungals such as ketoconazole ( Nizoral) or under HIV medication, like ritonavir (Norvir, Kaletra). Flonase can lower the blood cells that help fight off infections in the body. It is a must, therefore, to avoid being near people who are sick or have infections. Some conditions can really be serious or even fatal in people who are using this medication. Immediately call your doctor if you are exposed to measles or chicken pox and ask for preventive treatment. Flonase cannot be used when you are under an infection or if you have been sick. You have to wait until you get well before you can commence treatment. Also, inform your doctor if you have any of the following conditions: glaucoma or cataracts; liver disease; herpes simplex of the eyes; tuberculosis; sore or ulcers inside the nose; recent surgery or injury to the nose.

Tuesday 23, Jun 2009

  Steroid Nasal Spray Effective against Hay Fever

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Steroid Nasal Spray Effective against Hay FeverResearchers from the University of Chicago have found that fluticasone propionate (Flonase), a corticosteroid nasal spray, is more effective than a combination of popular anti-allergy drugs loratidine (Claritin) and montelukast (Singulair) when it comes to controlling seasonal allergies.

The findings of this study were presented at the 58th annual meeting of the American Academy of Allergy, Asthma and Immunology.

Robert Naclerio, M.D., professor of surgery at the University of Chicago and director of the study, remarked that the measures of inflammation were considerably better for Hay fever patients who were taking fluticasone propionate.

During the study, it was found that the use of nasal spray results in fewer eosinophils in patients’ nasal passages and patients using steroid nasal sprays displayed minimal side-effects and had lower levels of eosinophil cationic protein, an inflammation sign.

Naclerio remarked that fluticasone may be a better first choice for the treatment of seasonal allergic rhinitis because of its benefits and low cost.