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Monday 02, Aug 2010

  Bone complications possible with genetic reasons

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Bone complications possible with genetic reasonsDr Christina Haston, a researcher of the McGill University Health Centre research Institute, has remarked that genetic reasons are to be attributed as the cause behind bone complications accompanying cystic fibrosis.

The research article was published in the American Journal of Respiratory and Critical Care Medicine and the study was funded by the Canadian Cystic Fibrosis Foundation, the Canadian Institutes for Health Research, Valorisation Recherche Quebec, and the Fonds de la Recherche en Santé du Québec.

It was disclosed by this study that fragility of the bone can be attributed to genetics; this finding is expected to have critical implications for altering therapeutic practices.

Thursday 13, May 2010

  Genetic cause behind bone complications because of cystic fibrosis

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Genetic cause behind bone complications because of cystic fibrosisGenetic reasons have been suggested as the cause behind bone problems that generally accompany cystic fibrosis, according to a recent study by Dr Christina Haston, a researcher of the McGill University Health Centre research Institute.

The study by Dr. Haston suggested that genetics contribute to bone frailty, a finding that might have some implications in modifying therapeutic practices.

The research article was published in the American Journal of Respiratory and Critical Care Medicine and the study was funded by the Canadian Cystic Fibrosis Foundation, the Canadian Institutes for Health Research, Valorisation Recherche Quebec, and the Fonds de la Recherche en Santé du Québec.

Friday 22, Aug 2008

  Which plays a bigger role in sports – genetics or steroids?

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Victor Conte steroidsFormer BALCO boss Victor Conte has hinted in his letter to the New York Daily News that the sporting world should take a closer look on athletes originating from the Caribbean. Conte says that countries like Jamaica and other Caribbean nations do not have independent anti-doping federations and practice “minimal offseason testing” and, therefore, are of suspect of using steroids. An excerpt from Conte’s letter:

I have no evidence of doping by any of the winners of medals in Beijing, but when times begin falling like rain, questions arise, especially when the record-setters are from countries such as Jamaica and other Caribbean nations….

Conte mentions that in the women’s 100-meter event four of the eight finalists were from the region and Jamaican athletes took the 1-2-3 places in said event with Shelly-Ann Fraser taking home the gold.

He also mentions Jamaica’s Usain Bolt and Trinidad and Tobago’s Richard Thompson who won the gold and silver medal in the 100 meters respectively. Conte describes Bolt’s victory as “a shocking world-record time of 9.69, which is almost unbelievable since he shut it down before the finish line.”

Conte might know the top-secret protocol of doping; however, could he be totally right to hint that these personalities should be under a cloud of suspicion, as he puts it, because of possible use of performance-enhancing drugs?

In the ongoing Olympics, it’s obvious that the track is being dominated by athletes of African ancestry. And if you’re going to mention preeminent figures in Olympic sprinting and running events you’re going to come up with names like Marion Jones, Michael Johnson, Khalid Khannouchi, Donovan Bailey and Maurice Greene. These athletes have one common denominator – their ancestral origin is Africa.

Jon Entine in his The Story Behind the Amazing Success of Black Athletes offers an explanation to this phenomenon and it is not, in any way, connected with steroids.

Genetically linked, highly heritable characteristics such as skeletal structure, the distribution of muscle fiber types, reflex capabilities, metabolic efficiency, lung capacity, and the ability to use energy more efficiently are not evenly distributed among populations and cannot be explained by known environmental factors.

Although scientists are just beginning to isolate the genetic links to those biologically-based differences, it is indisputable that they exist. Each sport demands a slightly different mix of biomechanical, anaerobic, and aerobic abilities. Athletes from each region of the world tend to excel in specific events as a result of evolutionary adaptations to extremely different environments that became encoded in the genes.

Genes, it seems, play major role in on one’s athletic performance. This is why, the article says, whites of European ancestry dominate sports like weightlifting, wrestling, shot-put and hammer. People of this race have “on average, more natural upper-body strength” because they have the mesomorphic body type which such events require – large and muscular, particularly in the upper of the body, with relatively short arms and legs and thick torsos.

This body structure is proving to be an advantage in sports where strength rather than speed is the winning asset.”

East Asians, on the other hand, are a presence in diving, gymnastics and figure skating because they tend to be small and more flexible.

On black athletes Entine says that “there are a range of structural traits shared by genetically-diverse African athletes: low body fat, longer legs in comparison to the rest of their bodies, and narrow hips.”

Here are some of the characteristics enumerated by Entine that explain why black athletes, particularly of West African descent, monopolize the Olympic track today.

•    relatively less subcutaneous fat on arms and legs and proportionately more lean body and muscle mass, broader shoulders, larger quadriceps, and bigger, more developed musculature in general;
•    denser, shallower chests;
•    higher center of gravity, generally shorter sitting height, narrower hips, and lighter calves;
•    longer arm span and “distal elongation of segments” – the hand is relatively longer than the forearm, which in turn is relatively longer than the upper arm; the foot is relatively longer than the tibia (leg), which is relatively longer than the thigh;
•    a higher percentage of fast-twitch muscles and more anaerobic enzymes, which can translate into more explosive energy.