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Friday 26, Feb 2010

  Frailty in older women possible of being treated with appetite-stimulating hormone

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Frailty in older women possible of being treated with appetite-stimulating hormoneGhrelin, a hormone that stimulates appetite, can be used as an effective option for offering relief to older women suffering from clinical frailty. This finding was revealed by a study presented by Penn Medicine researchers at ENDO, The Endocrine Society’s 91st Annual Meeting.

Frailty is a common geriatric syndrome that is characterized by unintentional weight loss, exhaustion, weakness, and low levels of anabolic hormones prompting increase in risk of falls, hospitalizations, disability, and even death.

Anne Cappola, MD, ScM, Assistant Professor of Medicine in Endocrinology, Diabetes, and Metabolism at the University of Pennsylvania School of Medicine, said that efforts to identify ways for preventing or treating common geriatric conditions has become highly important today due to the associated severe health consequences.

Wednesday 24, Jun 2009

  Appetite-stimulating Hormone to guard Muscle against Atrophy

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Appetite-stimulating Hormone to guard Muscle against AtrophyResearchers have found a potential new form of treatment to help patients fight against the common ailments of muscle atrophy.

Muscular Atrophy is a debilitating process that results in an extensive loss of muscle function and mass resulting in worsening of quality of life. It can take place with aging and inadequate food intake; it may also develop as a result of nerve injury.

Des-acyl ghrelin, which is a form of ghrelin and an appetite-stimulating hormone in the body, is the new form of treatment as per Andrea Graziani, PhD., study’s co-author, molecular biologist with the Department of Clinical and Experimental Medicine and the Biotechnology Center for Applied Medical Research, University of Piemonte Orientale, Novara, Italy.

This study by Graziani and his team is expected to open new treatment avenues for treating all possible forms of atrophy. The study was supported by Telethon, Regione Piemonte, and the Italian Ministry for University and Research.