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Thursday 30, Aug 2012

  Frankie Andreu Responds To Ban On Armstrong

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Frankie Andreu Responds To Ban On Armstrong – Cliff Notes

Frankie Andreu doping lance armstrongA professional from 1989 to 2000 and a member of the US Postal Service team’s roster during the first two Tour de France victories of Lance Armstrong in 1999 and 2000, Frankie Andreu, has expressed surprise that a fighter on the field like Armstrong has decided not to fight the doping charges against him.

Frankie Andreu is a former professional cyclist who was the team captain of the U.S. Postal Service cycling team along with Lance Armstrong in 1998, 1999, and 2000. He admitted that he was introduced to performance enhancing drugs in 1995 while he was riding for Motorola.

Andreu said while discussing the ban of Armstrong that Lance is a fighter and the fact that the U.S. Anti-doping Agency (USADA) has enough information to strip him of his Tour de France titles is surprising.

In 2010, Frankie Andreu and his wife Betsy told a federal agent investigating the case of Armstrong and other cyclists that Lance admitted to using performance enhancing drugs in a hospital room while battling cancer in 1996, which was vehemently denied by Armstrong.

In 2006, Frankie and his wife were called to testify under oath at a civil suit between Armstrong and SCA Promotions in a case where the underwriter (SCA Promotions) refused to pay a bonus of $5 million for his sixth Tour victory because of allegations Armstrong had used banned substances in order to win. At the hearing, the Andreus testified that Lance admitted to using a list of substances, including growth hormone, cortisone, EPO, anabolic steroids, and testosterone to his doctors. In the same, the primary doctor of Lance submitted an affidavit that he had never seen any evidence that indicated that the cyclist admitted to taking performance enhancing drugs.

In an article appearing in the New York Times in 2006, Lance Armstrong said Betsy lied because “she hates me” and Frankie lied because “he’s trying to back up his old lady.” The statement of Armstrong also suggested that the wife of Frankie Andreu may have got confused with possible mention of his post-operative treatment that included anabolic steroids and EPO, which are routinely prescribed to counteract wasting and red-blood-cell destroying effects of intensive chemotherapy.

Frankie Andreu Responds To Ban On Armstrong – Video

Frankie added that Armstrong’s statement accusing USADA of unconstitutional witch hunt left him unimpressed and added that the efforts of the anti-doping agency is to punish dopers and he fully supports that. He added that doping bans by USADA to cheaters would send a pointed lesson to all the riders that the sport is changing and it is for the better. Frankie remarked that only riders can clean up cycling and added, “There’s always going to be the guy who denies and denies that he’s ever used something,” Frankie said. “Nobody really knows what that guy is really doing when he goes home and closes the door.”

Armstrong, in replies of accusations of drug use, said he has been tested hundred times for performance enhancing drugs. He only tested positive for positive for cortisone at the 1999 Tour but was not penalized after he produced a prescription from a doctor that the cortisone was in a skin cream he used for saddle sores.

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Sunday 29, Jul 2012

  Athletes Banned For Doping In Lead-Up To Olympics

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World Anti-Doping Agency President John Fahey recently announced the results of a program that was designed to test athletes under suspicion before they arrived in London.

At least 107 athletes drew doping bans, ruling them out of the games, in the six months to mid-June, Fahey said and acknowledged that perhaps not all would have qualified to compete.
“Had that been their ambition, then I am pleased to say that they are not with us in London,” Fahey told the International Olympic Committee’s annual gathering.

Some of the Athletes who tested positive for Doping with Performance Enhancing Drugs (PEDs)

In another announcement, the International Association of Athletics Federations (IAAF) handed over lengthy bans to nine track and field athletes for doping violations in a crackdown on the use of prohibited substances in the lead up to the London Olympics.

The nine athletes, include Olympic bronze medalist Nataliya Tobias, have tested positive for “sophisticated doping” offenses. Six of these athletes (Morocco’s Abderrahim Goumri, Greece’s Irini Kokkinariou, Turkey’s Meryem Erdogan, and three Russians — Svetlana Klyuka, Nailiya Yulamanova, and Yevgenina Zinurova) were caught for using a new “biological passport” method that builds up a profile of each over a period of time. Erdogan, Klyuka, Yulamanova, and Zinurova admitted the offense and waived the right to a “B” sample.

The remaining three, including Olympic bronze medalist Nataliya Tobias, were suspended after further analysis of samples they gave at the World Championships in Daegu last year. Bulgaria’s Inna Eftimova tested positive for a synthetic growth hormone, while Ukrainian Antonina Yefremova was charged after synthetic testosterone was found in their systems. All the three athletes admitted the offense and waived the right to a “B” sample.

“Today’s announcements underline the IAAF’s continued and unwavering campaign against doping in athletics,” IAAF President Lamine Diack said in a statement. “They demonstrate the IAAF’s commitment to use advanced methods to detect doping and to enforce increased sanctions when justified. We will not stint in our resolve to do everything in our power to eradicate cheating.”

London Olympics 2012: Doping Scandal (RT)

Moroccan runner Mariem Alaoui Selsouli was also suspended by the IAAF from the London Olympics after she tested positive for doping. Selsouli tested positive for the diuretic furosemide at the Paris Diamond League meeting on July 6, the governing body said. The runner became an Olympic medal favorite after clocking 3 minutes 56.15 seconds in the 1,500 meters.

”Selsouli has waived her right to the B (backup sample) analysis, and as a result has now been provisionally suspended from all competition in athletics,” the IAAF said in a statement.
The World Anti-Doping Agency list of prohibited substances includes Furosemide and is used by sportsmen as a masking agent for disguising the presence of performance enhancing drugs.

According to another announcement, Greek athlete Paraskevi Papachristou was expelled for posting an offensive comment about African immigrants on Twitter. “With so many Africans in Greece, the mosquitoes from the West Nile will at least be eating some homemade food,” Papachristou said on Twitter.

“I would like to express my heartfelt apologies for the unfortunate and tasteless joke I published on my personal Twitter account,” she later wrote on Facebook.

pdf_iconDownload in PDF: Athletes Banned For Doping In Lead-Up To Olympics

Friday 13, Apr 2012

  Masteron Enanthate- Drostanolone Enanthate

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The world of professional sports does not provide endless opportunities to sportsmen and this is the reason why they need to deliver as and when asked and this “invincibility” is more or less accomplished by those into sports by using performance enhancing drugs such as Masteron enanthate.

Having an anabolic androgenic ratio of 62:25 and an active life of nearly 8 days, Masteron enanthate (also known as Drostanolone enanthate) is best used in doses of 400-600 mg per week by men and 100 mg per week by women. It has the molecular weight of 360.5356 g/mol at the base and can be detected over a period of three months. The anabolic steroid is commonly stacked with long estered cutting cycle steroids such as Trenbolone Enanthate, Clenbuterol, Ephedrine, T3, growth hormone, IGF, and Testosterone.

This steroid is commonly made the part of a pre-contest or an off-season program for adding new muscles while retaining existing muscles. The derivative of DHT (dihydrotestosterone), Masteron enanthate does not convert to estrogen and has the potential to inhibit blocking the conversion of free testosterone to estrogen by aromatization pathway besides enhancing the active free testosterone levels in the circulation. In addition to these advantages, Drostanolone enanthate is also admired for negating the side effects of estrogens and promoting fine muscle details being accentuated like striations. Furthermore, Masteron enanthate is also beneficial to draw out water from between the skin and the muscle to result in a very cut look at low body fat levels.

Last but not the least, Masteron enanthate is a potent anabolic steroid and must be used for legal purposes and under strict medical regulation.

Tuesday 10, Apr 2012

  Hexarelin

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Hexarelin, a powerful GH-releasing peptide, is one of the most admired drugs when it comes to stimulating the release of growth hormone (GH).

Hexarelin has the chemical name of L-Histidyl-2-methyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide; {HIS}{D-2-ME-TRP}{ALA}{TRP}{d-PHE}{LYS}-NH2 and the molecular formula of C47H58N12O6.

The peptide, Hexarelin, is superior to GHRH and GHRP-6 in stimulating GH release and can easily stimulate the secretion of GH, ACTH (adrenocorticotropic hormone), cortisol, and prolactin during sleep. The seven-amino acid peptide is considered more effective and long lasting than GHRH (growth hormone releasing hormone) and a potent GH releasing peptide combination is experienced when Hexarelin is combined with GHRP-6 (Growth Hormone Releasing Peptide–6) compared to pairing of GHRH with GHRP-6. The combination (Hexarelin and GHRP-6) is associated with dramatic enhancements in terms of circulating IGF-1 concentrations in addition to improvements in the terms of serum IGF-1, IGF-binding protein-3 concentrations, and promotion of linear growth. Hexarelin is also beneficial in reestablishing the levels of Insulin-like development factor-I and growth hormones.

One of the biggest reasons why Hexarelin is popular among professional sportsmen is because this performance enhancing drug has the unique potential of promoting growth of new muscle fibers, increase body strength, and increase size of existing muscle fibers. In addition to these advantages, Hexarelin is also useful in promoting neural protection, joint rejuvenation, protection and healing, and fat reduction. It is also beneficial when used with growth hormone and IGF as Hexarelin restores the natural levels of hormones, such as testosterone, which may have been negatively affected by IGF and GH use.

The recommended dosage of Hexarelin is 200 mcg per day when used via subcutaneous injections and should be stored at a controlled room temperature of 20° to 25°C (68° to 77°F) to maintain its efficacy and shelf life.

Sunday 08, Apr 2012

  GHRP-6- Growth Hormone Releasing Peptide-6

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Belonging to the category of GH secretagogues, GHRP-6 or growth hormone releasing peptide-6 is a synthetic hexapeptide that is admired for stimulating the release of growth hormone (GH) by two completely different mechanisms. While growth hormone releasing peptide-6, on one hand, amplifies the natural GHRH signal transduction pathway, it also acts as a functional antagonist of the hormone to inhibit somatostain (GH secretion).

One of the biggest reasons behind the popularity of GHRP-6 is that it has positive effects on growth hormone release and its use is closely associated with the promotion of food intake by increasing hunger. Moreover, the synthetic hexapeptide is also helpful to aid metabolism and medically recommended to help patients suffering with complications such as growth hormone deficiency, eating disorders, obesity, and cachexia.

It is also useful in promoting muscle mass and strength enhancements besides leading to loss of body fat and weight besides promoting the rejuvenation and strengthening of joints, bone mass, and connective tissue. GHRP-6 may be used for re-stimulating the natural production of growth hormone, when the natural GH secretion has been inhibited by long-term synthetic usage, as it has a direct effect on the feedback loop that signals growth hormone release inhibition. In addition to all these advantages, GHRP-6 is also useful in promoting the sense of well being, healing of joints and tendons, and improving the natural production of growth hormone, besides increasing normal pulsatile physiological secretion level by its hypothalamic action and pulsatile secretory bursts of GH.

The recommended dosage of GHRP-6 is 400-600 mcg administered via subcutaneous method, divided in 2-3 injections and it must be kept at a controlled room temperature of 25°C (77°F) with excursions permitted up to 15-30°C (59-86°F) to maintain its shelf life.

Monday 12, Mar 2012

  Masteron Enanthate

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If you want to lose weight and gain solid muscles but concerned about estrogenic side effects such as gynecomastia, Masteron enanthate is an excellent choice for you. Use of this highly potent anabolic steroid is associated with dramatic and sustaining improvements in terms of body strength and fat loss.

The anabolic steroid is commonly used by sportsmen, especially those into body building and strength athletics, during a pre-contest or off-season program to add or retain size. Originally, Masteron enanthate was developed as an anti-estrogen (under the name Masteril) to treat breast cancer and was administered in a combination with Nolvadex but is now considered one of the most “exotic” androgenic anabolic steroids. This derivative of DHT (dihydrotestosterone) does not convert to estrogen and is very effective in blocking the conversion of free testosterone to estrogen by the pathway of aromatization. By doing this, it marginally increases the amounts of active free testosterone in the circulation and even negates the side effects of estrogens.

Masteron enanthate, which is also known as Drostanolone enanthate, has the chemical name of 17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one Enanthate. It has an active life of approximately eight days and can be detected up to three months. Masteron enanthate has an anabolic androgenic ratio of 62:25.

The recommended dose of Masteron enanthate is 400-600 mg per week for men and 100 mg per week for women. It is generally stacked with long estered cutting cycle steroids such as Trenbolone Enanthate, Clenbuterol, Ephedrine, T3, growth hormone, IGF, and Testosterone. Available in oral and injectable forms, this anabolic steroid can be easily and affordably purchased online with or without a medical prescription.

One of the best things about Masteron enanthate is that it promotes fine muscle details being accentuated like striations and is very effective drawing out water from between the skin and the muscle to offer a very cut look at low body fat levels.

Wednesday 15, Feb 2012

  GHRP-6

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If you want to reap the benefits of growth hormone, GHRP-6 (growth hormone releasing peptide-6) can help you in more than just a way. Classified as a peptide characterized by the release of growth hormone, GHRP6 is a synthetic hexapeptide that belongs to the category of GH secretagogues playing an important role in release of growth hormone by two completely different mechanisms.

The molecular formula of GHRP-6 is 46H56N12O6 and it has high performance liquid chromatography of 99.68 percent. It plays an all-important role in the inhibition of somatostain (GH) secretion for amplifying the natural signal transduction pathway of growth hormone releasing hormone (GHRH).

Medically, GHRP-6 is prescribed to promote improvements in normal pulsatile physiological secretion level through hypothalamic action and pulsatile secretory bursts of growth hormone. Besides this, GHRP-6 is also effective in the stimulation of hunger and intake of good besides being extremely useful to treat deficiency of growth hormone and disorders such as eating problems and obesity.

The recommended dose of GHRP6- is 400-600 mcg per week or 100 mcg per day via subcutaneous injections to boost body strength, stamina, and performance levels besides promoting the processes of fat burning and restoring the natural production of IGF-1 and GH. Growth hormone releasing peptide-6 is also considered beneficial to improve sleep patterns and the sense of well being. Use of GHRP-6 should not be made without recommendation of a qualified medical practitioner. GHRP-6 is required to be stored at a controlled room temperature of 25°C (77°F) with excursions permitted up to 15-30°C (59-86°F) for protecting its shelf life.

Tuesday 24, Jan 2012

  IGF-1

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Somatomedin C is a protein found in humans and is commonly termed as Insulin-like growth factor 1 (IGF-1).  It is one of the most important hormones responsible for growth in children and has a molecular structure and size similar to that of Insulin.  It has a molecular weight of 7649 daltons and consists of a peptide chain with 70 amino acids in a single chain having three intramolecular disulphide bridges.

It is associated with the peptide family, commonly identified as the growth factors. Known to be a highly anabolic hormone, it is produced in liver and the peripheral tissues particularly in the cells of skeletal muscles. The presence of the Human Growth Hormone (HGH) in the body is considered to trigger the release of IGF-1 as its response. It is one of the most sought after substances by bodybuilders for the reason that it initiates the development of muscles in a very short period. As a result of rigorous training, the body experiences an increase in the Growth Hormone (GH) as well as the IGF-1 which causes the muscle cells to grow. Where GH is considered to have very strong anabolic properties, it is IGF which is believed to be responsible for its primary anabolic nature.

Growth hormone is mainly produced in the anterior pituitary gland which then flows into the blood stream stimulating the liver to produce IGF-1.  As a result, IGF-1  then  leads to the systemic body growth  of all the cells in the body mainly those of the  skeletal muscles, cartilage, bone, liver, kidney, nerves, skin, hematopoietic cell and the lungs. Apart from IFG’s insulin-like effects, IGF-1 also initiates regulated cell growth and development in the nerve cells and cellular DNA synthesis.

Deficiency of any of these two substances causes stunted growth in children who are then given recombinant GH to restore their condition.  People suffering from IGF-1 often suffer from Laron syndrome (Laron’s dwarfism) and are treated with recombinant IGF-1.

Normally 98% of IGF-1 is always seen to be bound to one of 6 binding proteins (IGF-BP).  The protein responsible for 80% binding of IGF is IGFBP-3and is bound to it in 1:1 molar ratio.

When administered, IGF-1 leads to the building of new muscle tissue by initiating the synthesis of protein along with the retention of nitrogen in the body. The prime functions associated with this are hyperplasia, which causes an increase in the muscle tissue and mitogenesis or the growth of new muscle fibers. This makes IGF -1 a highly favoured option for bodybuilders and power lifters seeking not only their muscle development but growth of muscle fibers as well.

Another benefit of employing IGF-1 is that it has a strong effect on the lipid metabolism of the body. In other words, it also plays a significant role in burning the body fat at a relatively fast rate. IFG-1 is also known to be a neuroprotector as well as a neuropromotor and finds its use in the improvement of functions related to the mind like reflexes, memory and ability to learn.

IGF-1 is employed as one of the most important substances required for the production of connective tissue in the joints, thereby ensuring appropriate bone density.

Being a highly potent drug for the development of muscle mass and fat-cutting, IGF’s Lr3 IGF-1 version is also considered to be equally powerful. Here Lr3IGF-1 stands for Long R3 Insulin-like Growth Factor-I or Long R3IGF-I.  It is a peptide of 83 amino acid analog of human IGF-I consisting of an entire human IGF-1 sequence. However, the only difference is that there is a substitution of an Arg for the Glu at position 3 and 13 amino acid extension at the N-terminus of the peptide.  It is for this reason that Long R3IGF-I is comparatively considered to be a more potent drug.

Some factors believed to cause changes in the levels of growth hormone (GH) and IGF-1 are the user genetic make-up, time of the day it is taken, age, sex, exercise status, stress level, nutrition level and body mass index (BMI). Reduction in IGF-1 signaling is also associated with the contribution of ‘anti-aging’ effects during calorie restriction phase.

A word of caution here is that increased use of IGF is often associated with enhanced risk of cancer.

Monday 23, Jan 2012

  T3 Cytomel

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Cytomel is the market name for Liothyronine sodium and is the L-isomer of triiodothyronine (T3). It is one of the most potent forms of thyroid hormone and is used in the treatment of hypothyroidism and myxedema coma. It stands under the systematic (IUPAC) name of sodium (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl] propanoate.

Cytomel is a favoured drug because it acts fast and has a shorter biological half-life due to less plasma protein binding with thyroxine-binding globulin and transthyretin. In the body it is known to enhance the basal metabolic rate, initiate protein synthesis and increase body’s receptivity to catecholamines, particularly adrenaline by permissiveness.

There are two categories of thyroid hormone preparations. First is the Natural hormone preparation which is derived from an animal steroid and second is the synthetic preparation. Natural steroid includes desiccated thyroid derived from domesticated animals and thyroglobulin, derived from thyroid glands of the hog. The United States Pharmacopeia (USP) has standardized the total iodine content of natural preparations. In the body, this natural T3 initiates the process of oxidative metabolism of the energy producing food substrates or those stored in the fat, muscles and glycogen. This takes place in the mitochondria of our cells, which are popularly called the ‘powerhouses’ because it is here that energy for the consumption of the body is produced.

Consumption of Cytomel increases the absorption of nutrients into the mitochondria. It also leads to an increase in the rate at which these food particles are burned to produce energy. This takes place by catalyzing the activities of enzymes involved in the oxidative metabolic pathway of the oxidation process. Hence an increase in the metabolic rate means higher requirement of fuel in the body. And if the body happens to be in a hypocaloric state, it will start burning the fat in the body at even a higher rate. This primarily takes place because of increase in the ATP produced in the mitochondria. In other words, an increased in the level of ATP causes an increase in overall metabolic activity of the body which is why Cytomel is taken.

Here an important thing to be kept in mind is that since mitochondrion needs fuel to facilitate its production of energy, it uses anything that comes its way to do so. It means that it there aren’t any food substrates available for the body to produce energy, the body uses the fat, proteins and even glucose to draw its fuel from. It might also start to feed on the muscles in the body to create this energy. Considering this function of the mitochondria, it is imperative that Cytomel be taken along with other anabolic steroids. This is because if the user is on a diet while taking Cytomel and does not combine it with other anabolic steroids along with it, he might lose out a great amount of muscle.

Hence Cytomel plays an important role in optimizing the metabolic rate of the user’s body. This is exactly what bodybuilders tend to achieve during their training period. Because of its ability to synthesize protein at a fast rate, Cytomel use is considered to be one of the best options to be included during pre-contest dietary. This is because it helps in the elimination of what is called the ‘sticky fat’ or the fat which somehow doesn’t want to leave your body in the last weeks of your dieting.  Many experts think that instead of taking in the last phase to cut fat, it can be always be taken initially as well when one wants to burn maximum fat by increasing body’s metabolism.

For best results in minimum time, it is highly recommended that Cytomel be used with Insulin, Anabolic Steroids and the Growth Hormone. Cytomel proves to be very useful when taken with Clenbuterol as it stops the down regulation of beta 2 receptors caused by Clen.

It is best advised to use Cytomel for optimizing your body’s metabolic rate for 9 to 10 months a year. The remaining 2 to 3 months can be used as a recovery period.

Some common side effects associated with Cytomel (incase of heavy dosage for a prolonged period) are excessive sweating, stomach cramps, irritability, insomnia, vomiting, weight loss, headache, increased appetite, fever, and diarrhea.

Friday 30, Dec 2011

  Steroid supply leads to disgrace for doctor

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A doctor who is alleged to have a gang association and a reputation for supplying anabolic steroids to body builders has been struck off the register on charges relating to irregular prescribing.

Johannes Wilson, the doctor, was understood to have left the country and did not appear or defend himself at the Health Practitioners Disciplinary Tribunal (HPDT) hearing.

The doctor was found guilty in July 2006 of professional misconduct for three failed vasectomies on two men.

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