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Tuesday 31, Jan 2012

  Hall voters to be consumed by steroids era

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Barry Larkin, still glowing over his election to the Hall of Fame, was asked about next year’s sure-to-be-controversial vote: the first appearances of Barry Bonds, Roger Clemens, and Sammy Sosa on the Cooperstown ballot.

“All I know is playing and competing against some of these guys, they’re the best — period,” he said.

From Online.wsj.com:

The Steroids Era will be the focal point of next year’s Hall ballot, when 550-plus members of the Baseball Writers’ Association of America try to assess three of the most accomplished players in the sport’s history.

For all the home runs and wins, it’s a trio tainted with accusations that their statistics were boosted by performance-enhancing drugs during a period when there were no agreed-upon penalties in baseball for the use of steroids and human growth hormone.

“It’s going to be agonizing,” BBWAA general secretary Jack O’Connell said after Tuesday’s news conference, repeating the phrase for emphasis.

“I’m not going to vote for any of the people that are linked to steroids. I could change down the road, but that’s the real strong feeling I have now,” said Hal Bodley of MLB.com, the former lead baseball writer for USA Today.

Monday 30, Jan 2012

  Anavar

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If you are looking for a steroid that’ll help you cut your extra fat within shortest time possible, Anavar (Oxandrolone) is what you should opt for. Anavar is a mild steroid with very less androgenic element in it which makes it an ideal choice for burning body fat without losing muscle mass or its strength. This steroid is mildly anabolic and is one of the safest options to go for, if one intends to enhance his performance. Chemically Anavar is 17b-hydroxy-17a-methyl-2-oxa-5a-androstane-3-one with molecular weight of 306.4442 g/ml at the base.

One of the prime factors that make this steroid so highly desired is that it is very mild on the HPTA (Hypothalamic-Testicular-Pituitary-Axis) of the body. This is why it is so popular among professionals like body builders and power lifters. It offers immediate strength to the muscles without affecting the natural testosterone levels in the body. This process takes place when the synthesis of phosphocreatine is stimulated in the muscle cells. The greatest advantage of this is that there are no depositions of fluid in the joints after the synthesis takes place. This greatly helps bodybuilders and sportsmen gain muscle strength within very limited period of time without an increase in the body weight.

Anavar also shows best results when it is stacked with other steroids like Deca Durabolin, Dianabol and Testosterone compounds. In other words, it improves the muscle-developing ability of other steroids when combined with them.  For better results, one can stack Anavar with Equipoise, Winstrol, Clenbuterol, T3 Cytomel, and Trenbolone. Many sportsmen also combine it with the human growth hormone. Nolvadex, Femera and Arimidex are most suited options for post cycle therapy purposes. Anavar use happens to be one of the safest practices employed for such purposes.

Hence intake of Anavar is also medically advised to people suffering from disorders like involuntary weight loss such as Grave’s disease and acquired immunodeficiency syndrome (AIDS).  It is also used for the treatment of other ailments such as alcoholic hepatitis, Turner syndrome and anemia and has been certified by the U.S.F.D.A.  Medical researches have found its use for increasing muscle mass and body composition in people with severe surface-area burns. In many patients, it is used to prevent muscle wasting as well.

Another reason why this popular drug is used by body builders so much is that it suppresses appetite without harming the body metabolism. The fact that it does not aromatize to form estrogen, makes it most preferred during pre-competition phases.

Since this mild drug is already a derivative of dihydrotestosterone (DHT), it does not get converted to DHT in the body when consumed. This is why Anavar has a shorter half-life when compared to other anabolic steroids. Hence the risk of side effects such as gynecomastia and liver damage, in this case is minimal. It is only when this steroid is administered in very high quantities for a long period of time that it may show traces of side effects. Anavar however has always been termed as a user friendly steroid which makes it the most recommended drug among bodybuilders.  Those consuming the steroid are likely to see its results six weeks after its administration.

Apart from maintaining the natural testosterone levels in the body, Anavar use does not inhibit the release of GnRH (gonadotropin releasing hormone) and LHRH (luteinizing hormone releasing hormone), FSH (Follicle Stimulating Hormone), IGF1 (Insulin like Growth Factor 1), and GH (Growth Hormone) in the body, unlike the case in other anabolic steroids. One of the biggest benefits associated with use of Anavar is that its results are not age dependent. This is so because it is a best option for field professionals who need to stay clean when tested for drugs and still require to keep their weight as well as fat at bay.

One of the most desired aspects of Anavar use is that it does not lead to any weight gains or bulking of the body mass. Instead it cuts the extra fat and also renders strength to the muscles. This is the reason why use of Anavar is so famously opted by both men as well as women and women prefer using Anavar more often than males as it helps them add lean tissue to their body in a short span. Being very slightly androgenic in nature, the risk of virilization is negligible. Thus we often find Anavar being quoted as a Girl Steroid’.

No matter how friendly this drug is, it should not be abused knowingly or unknowingly. Over- use over a period of time might reveal certain changes such as dark urine, acne, muscle cramps, vomiting, nausea and mood swings. These happen only if the drug is used excessively or in disproportionately huge amounts.

Dosage of Anavar among women should not increase 10mg – 20mg a day.  Men are recommended to start with 50mg a day. However depending on the individual some might also begin the cycle with 80mg or even 100 mg per day. It is strictly advisable that Anavar should not be consumed for more than 6-8 weeks as the body might get immune to its action mechanism. One can always resume its use after a break. The active life of Anavar is for 8 to 12 hours and can be detected for almost 3 weeks.

Anavar being a popular drug can easily be bought from the market. It is widely purchased online by sportsmen and bodybuilders. It is available in varied forms such as injectables, capsules and tablets.

Tuesday 24, Jan 2012

  Player Union right to question HGH testing methods

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The ongoing standoff between NFL players with WADA and its American arm, USADA, over human growth hormone testing, is becoming intense with each passing day.

“To me it’s clear that WADA is more interested in bullying us into a test than in scientifically supporting and justifying their testing protocol,” NFL Players Association Executive Director DeMaurice Smith said.

From Washingtonpost.com:

The union has taken the brunt of public criticism for the delay in implementing an HGH test, but WADA is equally to blame for its lack of transparency and refusal to answer some basic questions the union is asking — questions that Congress and NFL Commissioner Roger Goodell also should be asking. Questions such as: Is there enough independently published medical science that validates the test? How was it devised, and its parameters established?

“That’s odd to me,” said Doping researcher Don Catlin, founder of the UCLA Olympic lab and the man who cracked the Bay Area Laboratory Co-Operative case. “I don’t understand it. Scientists with a good finding are usually crawling to get published in a peer-reviewed journal so the world can see it.”

Tuesday 24, Jan 2012

  IGF-1

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Somatomedin C is a protein found in humans and is commonly termed as Insulin-like growth factor 1 (IGF-1).  It is one of the most important hormones responsible for growth in children and has a molecular structure and size similar to that of Insulin.  It has a molecular weight of 7649 daltons and consists of a peptide chain with 70 amino acids in a single chain having three intramolecular disulphide bridges.

It is associated with the peptide family, commonly identified as the growth factors. Known to be a highly anabolic hormone, it is produced in liver and the peripheral tissues particularly in the cells of skeletal muscles. The presence of the Human Growth Hormone (HGH) in the body is considered to trigger the release of IGF-1 as its response. It is one of the most sought after substances by bodybuilders for the reason that it initiates the development of muscles in a very short period. As a result of rigorous training, the body experiences an increase in the Growth Hormone (GH) as well as the IGF-1 which causes the muscle cells to grow. Where GH is considered to have very strong anabolic properties, it is IGF which is believed to be responsible for its primary anabolic nature.

Growth hormone is mainly produced in the anterior pituitary gland which then flows into the blood stream stimulating the liver to produce IGF-1.  As a result, IGF-1  then  leads to the systemic body growth  of all the cells in the body mainly those of the  skeletal muscles, cartilage, bone, liver, kidney, nerves, skin, hematopoietic cell and the lungs. Apart from IFG’s insulin-like effects, IGF-1 also initiates regulated cell growth and development in the nerve cells and cellular DNA synthesis.

Deficiency of any of these two substances causes stunted growth in children who are then given recombinant GH to restore their condition.  People suffering from IGF-1 often suffer from Laron syndrome (Laron’s dwarfism) and are treated with recombinant IGF-1.

Normally 98% of IGF-1 is always seen to be bound to one of 6 binding proteins (IGF-BP).  The protein responsible for 80% binding of IGF is IGFBP-3and is bound to it in 1:1 molar ratio.

When administered, IGF-1 leads to the building of new muscle tissue by initiating the synthesis of protein along with the retention of nitrogen in the body. The prime functions associated with this are hyperplasia, which causes an increase in the muscle tissue and mitogenesis or the growth of new muscle fibers. This makes IGF -1 a highly favoured option for bodybuilders and power lifters seeking not only their muscle development but growth of muscle fibers as well.

Another benefit of employing IGF-1 is that it has a strong effect on the lipid metabolism of the body. In other words, it also plays a significant role in burning the body fat at a relatively fast rate. IFG-1 is also known to be a neuroprotector as well as a neuropromotor and finds its use in the improvement of functions related to the mind like reflexes, memory and ability to learn.

IGF-1 is employed as one of the most important substances required for the production of connective tissue in the joints, thereby ensuring appropriate bone density.

Being a highly potent drug for the development of muscle mass and fat-cutting, IGF’s Lr3 IGF-1 version is also considered to be equally powerful. Here Lr3IGF-1 stands for Long R3 Insulin-like Growth Factor-I or Long R3IGF-I.  It is a peptide of 83 amino acid analog of human IGF-I consisting of an entire human IGF-1 sequence. However, the only difference is that there is a substitution of an Arg for the Glu at position 3 and 13 amino acid extension at the N-terminus of the peptide.  It is for this reason that Long R3IGF-I is comparatively considered to be a more potent drug.

Some factors believed to cause changes in the levels of growth hormone (GH) and IGF-1 are the user genetic make-up, time of the day it is taken, age, sex, exercise status, stress level, nutrition level and body mass index (BMI). Reduction in IGF-1 signaling is also associated with the contribution of ‘anti-aging’ effects during calorie restriction phase.

A word of caution here is that increased use of IGF is often associated with enhanced risk of cancer.

Friday 20, Jan 2012

  HGH testing by MLB not effective

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The latest feat of Major League Baseball of extended “labor peace” with the Major League Players Association was reached on November 22, 2011.

MLB has apparently won out in its attempt to curb illicit use of human growth hormone (HGH) by its players, as per terms of the latest basic agreement between the parties.

From Sports-central.org:

The lockouts by both the NFL and NBA this year perhaps did not go by unnoticed by MLB brass in its seemingly under-the-radar collective bargaining talks with the MLBPA this past fall. MLB attempted to show up the other leagues’ rather unkempt labor relations.

And MLB Commissioner Bud Selig made it quite clear by way of his public display of self-aggrandizement during the week following a new collective bargaining agreement (CBA) was reached, that his is the first North American professional sports league to agree to such a test for HGH. And perhaps it was indeed Selig’s latest and greatest coup yet, in such a pronouncement, however yet to be realized.

The agreement will run five years in duration and expire on December 1, 2016. Article 39, Sec. 7 (b) of the NFL’s CBA states: “The parties confirm that the Program on Anabolic Steroids and related Substances will include both annual blood testing and random blood testing for human growth hormone, with discipline for positive tests at the same level as for steroids.”

Thursday 19, Jan 2012

  Charges against Bonds dropped

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Days after a judge upheld conviction of the slugger on an obstruction of justice count, federal prosecutors have dropped all the remaining charges against Barry Bonds.

U.S. District Judge Susan Illston was informed by via filed papers from the U.S. attorney’s office in San Francisco that it was dismissing the three charges of making false statements still pending against Major League Baseball‘s all-time home runs leader.

From Espn.go.com:

The deadline for prosecutors to start the process for a retrial on those charges was about 30 days away. Now, Bonds won’t face a new trial on accusations that he lied to a grand jury back in 2003 when he testified that he never knowingly received steroids or human growth hormone from trainer Greg Anderson, and that no one other than his doctors ever injected him with anything.

Assistant U.S. Attorney Matt Parrella declined comment.

Allen Ruby, the lawyer of Bonds, refused to discuss whether Bonds intended to appeal the obstruction conviction.

Tuesday 17, Jan 2012

  Police officers jailed after steroids plot

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Two disgraced St Helens-based police officers will spend time in jail after admitting being part of a plot to deal illegal and dangerous bodybuilding drugs.

Detective Constable Paul Fletcher and Sergeant Paul Hornby were exposed by an undercover police officer and it was found that they were involved in the supply chain of anabolic steroids and human growth hormone.

From Sthelensstar.co.uk:

Fletcher, aged 47, was sentenced to the most severe punishment of seven and a half years in prison after Liverpool Crown Court was told he also admitted leaking confidential information to an underworld criminal about the arrest of four men following a house burglary in Dentons Green.

He also offered advice to a suspect who was being investigated for firearms offences and revealed the identity of a police informant, placing him in danger.

Fletcher, of Downall Green Road, Wigan, even encouraged his son, Paul Fletcher Jr., to enter the world of criminality and deal in steroids.

Tuesday 17, Jan 2012

  Shot-putter Carl Fletcher banned

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After being convicted of trafficking anabolic steroids by UK Anti-Doping, shot-putter Carl Fletcher has received a suspension of four years.

Fletcher was sentenced to nine months in prison drug offences including the supply of a number of anabolic steroids, including testosterone, human growth hormone, and Trenbolone, all of which are banned under the code of World Anti-Doping Agency.

From Guardian.co.uk:

Fletcher, who was provisionally suspended from all competition on 8 November, is banned from participation in sport until 7 November 2015.

The UKAD chief executive, Andy Parkinson, said the case demonstrated the extent to which it was increasingly working with law enforcement agencies, in this case including Merseyside police and the Serious Organised Crime Agency.

“This case proves the invaluable role that law enforcement agencies have in the fight against doping in sport and demonstrates that our intelligence system is working effectively,” he said.

“I would like to thank Merseyside police and Soca for their vital assistance in helping our intelligence team with this case. By attacking the supply chain and those that supply performance-enhancing substances, we stand a better chance of protecting the right of the clean athletes to compete in doping-free sport,” Parkinson said.

Sunday 15, Jan 2012

  WADA stays ahead of cheats

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The World Anti-Doping Association knows micro-dosing, testosterone patches, and sample manipulations are going on and the anti-doping agency is confident it is getting better at catching the cheats.

“Nothing surprises me,” director-general David Howman said. “There are many examples of athletes being stupid because they know there’s going to be a full programme at events like this and yet they still take the risk. I don’t understand it and I don’t think there will be an example where it doesn’t happen.”

From Nzherald.co.nz:

Wada is getting more scientifically savvy, but recognises that people are paying smart people large sums of money to stay ahead of the pack.

That is why it has forged an alliance with Interpol and is using a more investigative-based approach to catching cheats.

“There are more examples nowadays of micro-dosing, where substances can go in and out of the body reasonably quickly. We have more cases of manipulation, where athletes can manipulate their samples, and so we have to be wary.”

“Those who are supplying the drugs are making a lot of money. There are many countries where it is legal to distribute steroids, to distribute EPO, to distribute human growth hormone. Why not invest in that business and make a lot of money? We need to stop that,” Howman said.

Tuesday 10, Jan 2012

  HGH testing in new collective bargaining agreement

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The new collective bargaining agreement of the Major League Baseball will include blood testing for human growth hormone.

A report in the New York Times said testing would begin in February during spring training.

The penalty for a positive HGH test will be the same as a positive steroid test — a 50-game suspension, according to the sources.

From Espn.go.com:

Baseball’s new labor contract also will include a rise in the minimum salary to $480,000 and luxury taxes on both amateur draft signings and international free agents coming to the major leagues.

There also will be a slight increase in the total of players eligible for salary arbitration after the 2012 season, when there also will be a new method to determine compensation for clubs losing top major league free agents. There also will be modifications to the luxury tax on high-payroll teams, but the threshold will remain at $178 million next year.

Sources told ESPN.com’s Jayson Stark that labor negotiators of the MLB have reached a “handshake agreement” on all major issues.

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