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Sunday 02, May 2010

  Intravenous Immunoglobulin minimizes insensitivity to steroids

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Intravenous Immunoglobulin minimizes insensitivity to steroidsPeople suffering from severe asthma and insensitive to steroids require less of the medication and spend less time in the hospital when compared with those using intravenous immunoglobulin (IVIG) in conjunction with steroids. This finding was disclosed by a research published in the Journal of Allergy and Clinical Immunology.

Researchers were of the view that IVIG increases the sensitivity of the lungs to steroids in part by minimizing lung inflammation.

Erwin Gelfand, M.D., a pediatric immunology and asthma specialist and chair of the Department of Pediatrics at National Jewish Medical and Research Center, said he has noticed asthmatic patients who required high doses of steroids in order to control the disease.

Tuesday 13, Apr 2010

  Insensitivity to steroids reduced by Intravenous Immunoglobulin

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Insensitivity to steroids reduced by Intravenous ImmunoglobulinAccording to a research published in the Journal of Allergy and Clinical Immunology, patients suffering from severe asthma and insensitive to steroids spend lesser time at the hospital beside needing less of the asthma medications while using intravenous immunoglobulin (IVIG) in conjunction with steroids.

It was remarked by Erwin Gelfand, M.D., a pediatric immunology and asthma specialist and chair of the Department of Pediatrics at National Jewish Medical and Research Center that many incidences have been noticed in which asthma patients need high doses of steroids for controlling the disease.

The researchers were of the view that IVIG increases the sensitivity of lungs to steroids to result in reduced lung inflammation.

Monday 23, Nov 2009

  Children with Kawasaki’s disease can benefit from steroids

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Children with Kawasaki's disease can benefit from steroidsAccording to a study that was published in an issue of Pediatrics, steroids can prove their real worth when it comes to reducing damage to the heart in children with Kawasaki’s disease.

This study was quick to highlight knowledge gap among members of the medical fraternity for treating Kawasaki’s disease since the present guidelines from the American Academy of Pediatrics suggest that there is little evidence for suggesting the effectiveness of steroids for treating children with Kawasaki’s disease and reducing damage to the heart.

Stephen Aronoff, MD, lead author of the meta-analysis and Temple University School of Medicine professor and chair of pediatrics, said that a multi-center study will be more than useful in justifying steroid treatment benefits for Kawasaki’s disease.

The study also brought forward recommendations being made available for the standard treatment of Kawasaki’s via aspirin and intravenous immunoglobulin (IVIG).

Sunday 16, Aug 2009

  Steroids considerably minimize damage to heart in children with Kawasaki’s disease

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Steroids considerably minimize damage to heart in children with Kawasaki's diseaseAccording to a study published in an issue of Pediatrics, steroids possess the ability to considerably minimize damage to heart in children with Kawasaki’s disease.

The new finding addresses a knowledge gap as the present guidelines from the American Academy of Pediatrics state that concrete evidence for steroid treatment is still lacking and recommendations are been made for the standard treatment of Kawasaki’s via aspirin and intravenous immunoglobulin (IVIG).

From News-Medical.Net:

“This gap in knowledge led us to examine the benefits of steroids more closely. We looked at research worldwide and were surprised to find eight solid clinical trials showing the value of steroids in significantly reducing heart damage in children with Kawasaki’s disease. Steroids, when combined with aspirin and IVGB, reduced the odds of developing inflammation of the heart blood vessels by half,” said Stephen Aronoff, MD, lead author of the meta-analysis and Temple University School of Medicine professor and chair of pediatrics.

Aronoff was of the view that a presently underway multi-center study will be able to provide any further evidence of benefits of steroid treatment for Kawasaki’s disease, which is considered to be one of the leading causes of acquired heart disease in children inflaming the blood vessels leading to the heart.

Friday 10, Jul 2009

  Intravenous Immunoglobulin Reduces Steroid Insensitivity

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Intravenous Immunoglobulin Reduces Steroid InsensitivityPeople with severe asthma who are insensitive to steroids need less of the medication, fewer bursts of it in emergencies and spend less time in the hospital when using intravenous immunoglobulin (IVIG) in conjunction with steroids.

IVIG is an antibody that is removed from the plasma portion of blood and is concentrated for use as a medication. IVIG regulates the immune system and has been shown to reduce inflammation in the lungs.

IVIG treatments cost several thousand dollars each month for people with severe asthma, but many health insurance companies cover the cost because, hence, IVIG can help lower emergency room and hospital use by patients with severe asthma.

Sunday 14, Jun 2009

  Heart Damage risk gets reduced with steroids in children with Kawasaki’s disease

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Heart Damage risk gets reduced with steroids in children with Kawasaki's diseaseAccording to a study in an issue of Pediatrics, it was revealed that steroids can significantly minimize the odds of heart damage development in children with Kawasaki’s disease. The findings of this study tend to address a knowledge gap as the present guidelines from the American Academy of Pediatrics suggest that the standard treatment is all about aspirin and intravenous immunoglobulin (IVIG).

Stephen Aronoff, MD, lead author of the meta-analysis and Temple University School of Medicine professor and chair of Pediatrics, told that this knowledge gap was the reason that motivated him and his team to examine the benefits of steroids.

Aronoff also remarked that if steroids can be combined with aspirin and intravenous immunoglobulin (IVIG), then the odds of developing inflammation of the vessels of the blood reduce by as much as half.

Kawasaki’s disease is responsible for inflaming the blood vessels leading to the heart. It is considered to be one of the leading causes of acquired heart ailment in the young age group. This ailment can turn into a life-threatening ailment if left untreated for more than 5-10 days.