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Friday 04, Jun 2010

  Extended relief possible for giant cell arteritis patients

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Extended relief possible for giant cell arteritis patientsPatients with giant cell arteritis (GCA) can expect a sigh of relief as a study has provided both hope and a practical treatment option for them.

It was found by researchers from Emory University and the Mayo Clinic that newly diagnosed GCA patients were able to considerably taper off use of an oral steroid and relapsed less in the following year with just three days of a high-dose intravenous steroid.

The study was published in an issue of the journal Arthritis & Rheumatism and the research was funded by the National Institutes of Health, the Dana Foundation, the Mayo Foundation and the National Institutes of Health General Clinical Research Center.

Wednesday 01, Jul 2009

  New Interventional Radiology Treatment offers New Paradigm

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New Interventional Radiology Treatment offers New ParadigmAs per a study, graft-versus-host (GHVD) Patients after a bone marrow or cord blood transplant with intravenous steroids who do not respond to the steroid treatment can be treated with higher doses of steroids with a new interventional radiology treatment.

It was found that higher doses of steroids can be given via catheter to the arteries, which are supplying the GHVD-affected organs since the remaining body is spared from side-effects of the steroids, as per Joshua L. Weintraub, M.D., chief of the Division of Vascular and Interventional Radiology at Mount Sinai Medical Center in New York City.

GHVD is a common complication, related to an allogeneic bone marrow transplant, in which the immune cells from the donated cord blood or marrow pose a threat to transplant patient’s body.

This first of its kind study in the United States reveals a viable option for treating patients with GHVD as per Weintraub.

Thursday 11, Jun 2009

  Intravenous Steroids Offer Safe And Practical Treatment For GCA

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Intravenous Steroids Offer Safe And Practical Treatment For GCAA new study offers practical treatment for patients with giant cell arteritis (GCA). Researchers from Emory University and the Mayo Clinic have found that newly diagnosed GCA patients respond well with just three days of a high-dose intravenous steroid. These patients had fewer relapse in the following year and they were also able to taper off the use oral steroids.

For the last 40 years, physicians have been able to treat and reverse some symptoms of GCA by prescribing prednisone, to be taken daily over a year or more. According to Dr. Cornelia M. Weyand, patients improve promptly and reliably, within days of when treated with high-dose intravenous steroid.

Although oral steroid provide relief, Dr. Weyand said that GCA patients are at risk of developing side effects since they have to take prednisone for a long time and in high doses. This can produce side effects such as hypertension, diabetes and osteoporosis. The team claimed that intravenous steroid can help avoid long-term use of steroids.

Saturday 16, May 2009


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CORTICOSTEROIDS IN ULCERATIVE COLITIS CUREA steroid for treatment for ulcerative colitis is corticosteroids. It can suppress the inflammatory response and manage symptoms. According to the report drug therapies for ulcerative colitis basically aims to induce remission and prevent flare-ups (maintain remission).this treatment mainly includes the corticosteroids, which does most of the works.

In case to reduce acute inflammation corticosteroids (steroids) may be accompanied or used alone. Steroids may be used rectally as an alternative to an aminosalicylate only if the disease is limited to the last end of the intestine. Forms taken by mouth may treat moderate-to-severe cases. Intravenous steroids are also advised to those who are less responsive towards less aggressive treatments.

If Drug therapy can bring the disease to the stage of remission and keep it functioning without causing significant side effects, it is considered successful. The patient’s condition is generally considered in remission when the intestinal lining has healed and symptoms such as diarrhea, abdominal cramps, and tenesmus (straining painfully or ineffectively to defecate or urinate) are normal or close to normal.

Other types of drugs can also be used along with corticosteroids to treat particular conditions and symptoms related with ulcerative colitis and Anti-diarrhea medications such as loperamide (Imodium) may be given to help control diarrhea. On the basis of the information it can be conclude that the corticosteroids are effective in the treatment of the ulcerative colitis.