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Tuesday 08, Jun 2010

  Mysterious disease behind self-attack by immune system

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Mysterious disease behind self-attack by immune systemA mysterious disease has been identified by physicians at the University of Florida. This disease leads to a self-imposed attack by the immune system on itself along with sending a warning signal to alert doctors at the onset of its worst symptoms.

Doctors are still unaware about an option for identifying which all of their patients have this unpredictable autoimmune disorder lupus with dangerous and life-threatening aspects, as per the Lupus Foundation of America.

Lupus, the disease, is a result of overactivity of immune system of the body and doctors generally prescribe immunosuppressant drugs for kidney disease treatment, including steroids, for treating this complication.

Saturday 08, May 2010

  Mysterious disease causes immune system to attack itself

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Mysterious disease causes immune system to attack itselfPhysicians at the University of Florida have found that a mysterious disease can cause immune system of the body to turn against itself besides sending a warning signal for alerting doctors at the onset of its worst symptoms.

According to the Lupus Foundation of America, doctors are still unaware about a method to identify which of their patients have the unpredictable autoimmune disorder lupus with dangerous and life-threatening aspects.

It is important to note here that since lupus is a result of overactivity of the body’s immune system, doctors prescribe immunosuppressant drugs for kidney disease treatment, including steroids.

Thursday 22, Apr 2010

  Severe kidney disease can be caused by mutant gene

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Severe kidney disease can be caused by mutant geneRecessive mutations in a gene called phospholipase C epsilon or PLCE1 can lead to a severe, early-onset form of kidney disease and renal failure in children, a previously unknown cause. This finding was revealed by scientists at the University of Michigan Medical School.

The mutant gene identification is important for the scientists since PLCE1 affects the development of podocytes, which are specialized cells playing a vital role in the kidney’s ability to remove waste products from blood and retaining important blood proteins.

Friedhelm Hildebrandt, M.D., the U-M’s Frederick G L Huetwell Professor for the Cure and Prevention of Birth Defects, said this is the first report of infants with two mutations in a recessive gene for nephrotic syndrome (resistant to steroid treatment) that nevertheless responded to treatment with steroids.