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Wednesday 08, Jul 2009

  Steroids Increase Myelin Synthesis

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Steroids Increase Myelin SynthesisSteroids help to reduce inflammation, but University of Illinois scientists suggest they also could be used to reverse a loss of myelin – a major problem in multiple sclerosis and other demyelinating diseases and injuries associated with the central and peripheral nervous systems.

Treatment of MS already includes the use of steroids, because they relieve inflammation and speed remission. However, new findings indicate that the steroids dexamethasone and progesterone actually signal the initiation and dramatically increase the rate of myelin synthesis.

What causes a loss of myelin demyelination – in MS cases is not known, but is believed to be the result of an abnormal immune response to bacteria and viruses. When myelin fails to form, it jeopardizes nerve communications leading to altered sensations and other complications. Demyelination is a focal point of research around the world.

Monday 04, May 2009

  Steroid Drug Methylprednisolone Can Treat Multiple Sclerosis

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Steroid Drug Methylprednisolone Can Treat Multiple SclerosisFindings from a study recently announced that a steroid drug can now be used to treat multiple sclerosis (MS) in addition to the usually prescribed MS drugs. This finding was part of the Late-breaking Science Program at the American Academy of Neurology’s 61st Annual Meeting in Seattle, held in April 25 – May 2, 2009.

In the study, 341 people with relapsing-remitting multiple sclerosis (MS) participated. Half of the participants were given both steroid drug methylprednisolone, plus the regular weekly treatment with the drug interferon beta-1a. Meanwhile, the other 50% of the participants were administered with the interferon drug plus a placebo. The participants who were administered with both drugs had 38 percent fewer relapses than those who were only given interferon drug.

These results showed that interfon work only moderate and not everyone responds fully to the treatment, but when combined with steroid drug methylprednisolone, more beneficial effects of controlling multiple sclerosis attacks.