08/12/2019 11:05 pm Welcome to isteroids.com - BLOG

Wednesday 23, Jun 2010

  Steroid concoction termed effective for patients with sinusitis

Posted By
Pin it Share on Tumblr

Steroid concoction termed effective for patients with sinusitisA steroid nasal wash was termed as effective option for treating symptoms of chronic sinusitis without affecting adrenal gland function, as per a small US study. Budesonide, the nasal wash, is yet to get approval from the FDA for treating chronic sinusitis.

As per researchers from the Washington University School of Medicine in St. Louis, this is the first-of-its kind study evaluating safety of such a nasal wash.

Chronic Sinusitis afflicts up to 14 percent of population in the United States and is a continuing inflammation of the nose and sinuses behind it.

Medical practitioners were advised by researchers to advise patients with sinusitis about the possible risks such as reduced bone mineral density that are linked with use of Budesonide in the long run.

Saturday 03, Apr 2010

  Sinusitis can be eased with steroid concoction

Posted By
Pin it Share on Tumblr

Sinusitis can be eased with steroid concoctionA steroid nasal wash, Budesonide, could prove to be an effective option for minimizing the symptoms of chronic sinusitis without resulting in any effect on adrenal gland function.

This finding was disclosed by a small US study. The drug, however, is yet to get approval from the FDA for treating the complication.

It was remarked by researchers from the Washington University School of Medicine in St. Louis that this is the first-of-its-kind study examining the safety of a nasal wash.

The researchers advised the doctors to communicate the risks associated with use of Budesonide such as decreased bone mineral density to the patients.

Wednesday 19, Aug 2009

  Budesonide found to reduce symptoms of chronic rhinosinusitis

Posted By
Pin it Share on Tumblr

Budesonide found to reduce symptoms of chronic rhinosinusitisBudesonide, a form of corticosteroid, used in asthma and nasal polyps, has been found to be effective in treating symptoms of chronic rhinosinusitis.

Rhinosinusitis is a new classification of sinusitis referring to the inflammation of the sinuses including the nose. A sinusitis is considered chronic if it persists for 12 weeks or more. It may occur with nasal polyps but there are cases without.

According to Neil Sachnadani, BS, and colleagues at the Washington University School of Medicine in St. Louis, a nasal wash containing budesonide and saline solution can improve clinical symptoms of rhinosinusitis.

The study was conducted by giving the participants a nasal wash with 0.25 mg budesonide in 5 ml saline solution. The participants have to apply the nasal wash in each nostril for 30 days. They were also made to answer a set of questionnaires relating to their symptoms and related quality of life. This was done before and after the study period.

A standard method of testing used was consyntropin injections. It stimulates the release of cortisol by the adrenal glands. This is to determine the adrenal response after budesonide therapy.

All participants reported some form of relief after therapy. Researchers also found that adrenal responses remained normal even after budesonide therapy. This indicates that budesonide is effective in treating rhinosinusitis without suppressing the adrenal function of the body.

From Eurekalert:

A nasal wash containing the corticosteroid budesonide appears to reduce symptoms of chronic rhinosinusitis without suppressing the function of the adrenal glands, a known complication of this type of drug that would indicate absorption throughout the whole body, according to a report in the March issue of Archives of Otolaryngology–Head & Neck Surgery, one of the JAMA/Archives journals.

Monday 15, Jun 2009

  Steroid Concoction can Ease Sinusitis

Posted By
Pin it Share on Tumblr

Steroid Concoction can Ease SinusitisBudesonide, a steroid nasal wash, can help in minimizing the symptoms of chronic sinusitis without affecting functions of the adrenal gland, as per a small US Study.

Chronic Sinusitis refers to a continuing inflammation of the nose and sinuses behind it, which affects up to 14 percent of the US Population.

Researchers from the Washington University School of Medicine in St. Louis said that this study was the first to examine safety of such a nasal wash besides noting that suppression of the functions of the adrenal gland is a known complication of Budesonide.

The FDA has yet to approve Budesonide as a nasal wash. This means that the nasal wash of this study would be an off-label use of the drug.

In the meanwhile, researchers advised doctors to advise patients about the risks associated with long-term use of Budesonide such as decreased bone mineral density.