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Tuesday 16, Nov 2010

  Some widely used supplements ineffective against osteoarthritis

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Some widely used supplements ineffective against osteoarthritisA research in 2006 reported that glucosamine and chondroitin, the widely used diet supplements, were no more effective against osteoarthritis than a placebo, except for a small benefit. Now a recently concluded study has suggested that the substances may be ineffective for them, too.

The study, published in the October issue of Arthritis and Rheumatism, found no significant difference between any of the four treatment options and the placebo.

Saturday 12, Jun 2010

  Hormone replacement in joint fluid complemented with positive regenerative effect

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Hormone replacement in joint fluid complemented with positive regenerative effectAccording to researchers from Germany, concentrations of testosterone in men and estrogen in women could have a positive effect on the regenerative potential of cartilage tissue.

In a study, it was suggested that hormone replacement in the joint fluid of men and women could be beneficial to treat late stages of human osteoarthritis (OA) by regenerating damaged tissue.

Results of this evidence-based study appeared in an issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

Thursday 27, May 2010

  Hormone can prevent long-term Osteoarthritis

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Hormone can prevent long-term OsteoarthritisParathyroid hormone (PTH), known as teriparatide in drug form, is the first ever drug that was recently found effective in preventing cartilage loss from osteoarthritis following injury to a joint. It was also found that the hormone can even regenerate some cartilage lost because of osteoarthritis.

This finding was disclosed at an early study presented September 12 at the annual meeting of the American Society for Bone and Mineral Research in Denver.

The study along with Randy Rosier, M.D., Ph.D., professor within the Department of Orthopaedics and Rehabilitation at the University of Rochester Medical Center was led by Erik Sampson, Todd O’Brien, Di Chen, Susan Bukata, J. Edward Puzas, Regis O’Keefe and Michael Zuscik within the Department of Orthopaedics and by Hani Awad in the Department of Biomedical Engineering at the University of Rochester Medical Center.

Wednesday 28, Apr 2010

  Potential regenerative effect seen by hormone replacement in joint fluid

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Potential regenerative effect seen by hormone replacement in joint fluidConcentrations of the sex hormones, testosterone in men and estrogen in women can have a positive effect on the regenerative potential of cartilage tissue as per German researchers.

It was suggested by the study that hormone replacement in the joint fluid of men and women can be advantageous for treating late stages of human osteoarthritis (OA) by regenerating damaged tissue.

Details of this evidence-based study appeared in an issue of Arthritis & Rheumatism, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

Sunday 18, Apr 2010

  Arthritis pain can be reduced by injecting gold into knees

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Arthritis pain can be reduced by injecting gold into kneesPatients affected by osteoarthritis can experience slowing down of the disease progression and pain getting eased with injecting gold into knees but this treatment form is not meant for every patient with rheumatoid arthritis, as per scientists.

As per the Arthritis Research Campaign, approximately 80 million people suffer from this condition and a further 350,000 people suffer from rheumatoid arthritis, which is an autoimmune joint disease where the joints in the body become inflamed.

It was remarked during the study that injecting gold into knees is not a same-treatment-for-all remedy as around 20-30 percent of the affected patients do not benefit from gold.

Friday 12, Mar 2010

  Steroid treatment for osteoarthritis knee victims does not progress disease

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Steroid treatment for osteoarthritis knee victims does not progress diseaseAccording to a review of the literature by researchers at The University of Auckland, steroid treatment for osteoarthritis knee victims does not progress disease as previously thought.

Associate-Professor Bruce Arroll, from the School of Population Health at the University, remarked that osteoarthritic knee pain is one of the primary causes of disability amongst older people.

The study, commissioned by the Accident Rehabilitation and Compensation Insurance Corporation, was co-authored by Dr Arroll and Dr Felicity Goodyear-Smith from The University of Auckland and was published in the British Medical Journal.

Thursday 18, Feb 2010

  PTH therapy highly effective for treating Osteoarthritis

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PTH therapy highly effective for treating OsteoarthritisAn osteoporosis drug may prove its addition worth by preventing cartilage loss arising due to osteoarthritis after a joint injury, as per an early study presented at the annual meeting of the American Society for Bone and Mineral Research in Denver.

Even though presently available drugs such as steroids or non-steroidal anti-inflammatory agents (e.g. Advil, Aleve) are effective for minimizing the level of associated pain yet they are ineffective for completely addressing loss of cartilage due to osteoarthritis that is believed to afflict more than 50 million Americans by 2020.

Physicians are often left clueless when it comes to restoration of cartilage in patients suffering from osteoarthritis, as per Randy Rosier, M.D., Ph.D., professor within the Department of Orthopedics and Rehabilitation at the University of Rochester Medical Center.

Saturday 06, Feb 2010

  Hormone holds promise for preventing joint injuries from resulting in osteoarthritis

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Hormone holds promise for preventing joint injuries from resulting in osteoarthritisAn existing drug for osteoporosis has been hailed as the first ever found for preventing loss of cartilage from osteoarthritis post joint injury besides being useful in regenerating some part of cartilage lost due to osteoarthritis.

This finding was presented on September 12, 2009 at the annual meeting of the American Society for Bone and Mineral Research in Denver.

Randy Rosier, M.D., Ph.D., professor within the Department of Orthopedics and Rehabilitation at the University of Rochester Medical Center, said physicians are presently left with no way to restore cartilage in patients who have lost it to osteoarthritis but the study results suggest that cartilage degeneration can be inhibited and the volume of cartilage in diseased joints be improved, at least in mice.

Thursday 21, Jan 2010

  Hormone promises to prevent long-term Osteoarthritis

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Hormone promises to prevent long-term OsteoarthritisParathyroid hormone (PTH), known as teriparatide in drug form, has been found useful in preventing loss of cartilage resulting from osteoarthritis following injury to a joint. It is also found to regenerate a part of cartilage lost due to osteoarthritis.

These findings were revealed by an early study presented September 12 at the annual meeting of the American Society for Bone and Mineral Research in Denver.

It is worth noting here that the presently followed drugs like steroids or non-steroidal anti-inflammatory agents (e.g. Advil, Aleve) can reduce pain but are unable to address cartilage loss due to osteoarthritis, which is believed to affect more than 50 million Americans by 2020.

The study was co-led by Erik Sampson, Todd O’Brien, Di Chen, Susan Bukata, J. Edward Puzas, Regis O’Keefe and Michael Zuscik within the Department of Orthopaedics and by Hani Awad in the Department of Biomedical Engineering at the University of Rochester Medical Center, and funded by the National Institutes of Health.

 


Friday 04, Dec 2009

  Osteoarthritis can be effectively treated with PTH therapy

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Osteoarthritis can be effectively treated with PTH therapyAn existing osteoporosis drug can prove to be an effective treatment option for preventing cartilage loss from osteoarthritis after a joint injury, as per an early study presented today at the annual meeting of the American Society for Bone and Mineral Research in Denver.

It is important to note that the presently available drugs such as steroids or non-steroidal anti-inflammatory agents (e.g. Advil, Aleve) can be good enough to minimize pain but are not capable of addressing cartilage loss behind osteoarthritis that is believed to afflict more than 50 million Americans by 2020.

According to Randy Rosier, M.D., Ph.D., professor within the Department of Orthopedics and Rehabilitation at the University of Rochester Medical Center, physicians are left with no answer when it comes to bringing back cartilage in patients who have lost the battle to osteoarthritis.

The results of this study, suggesting a slight restoration of cartilage, can prove helpful for physicians treating patients with osteoarthritis.

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