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Tuesday 04, Jan 2011

  Prematurity treatment put at rest with steroids

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Prematurity treatment put at rest with steroidsExpecting mothers administered with injections of steroids before giving birth face no increased risk of heart diseases at age 30 when compared to mothers receiving a placebo treatment.

This finding was disclosed in a study by University of Auckland that was published in the Lancet.

The study was supported by the Health Research Council of New Zealand, the Auckland Medical Research Foundation, and the New Zealand Lottery Grants Board.

Monday 22, Nov 2010

  Some dietary supplements may be risky for users

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Some dietary supplements may be risky for usersThe potentially beneficial bacteria and yeasts available as diet supplements and in some foods, probiotics, may not be as beneficial as widely believed.

A new study has suggested that probiotics can be deadly under certain circumstances.

The study was the largest randomized, double-blinded trial of its kind and published online in The Lancet.

Friday 27, Aug 2010

  Sore throat pain can be effectively managed with steroids

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Sore throat pain can be effectively managed with steroidsA single 10 mg dose of the steroid, dexamethasone can be useful in terms of safety, efficacy, and affordability for treating bacterial or viral pharyngitis (sore throat), as per a Mayo Clinic study published in an edition of Laryngoscope.

In a study involving 118 patients, it was revealed that patients given dexamethasone in a shot or a pill form reported pain relief four hours sooner than patients on placebo in pill or injection form.

Sixty seven percent of patients administered with steroids returned to normal activity in 12 hours and 84 percent returned to normal activity in 24 hours.

Monday 09, Aug 2010

  Increased rejection occurrence noticed with early withdrawal of steroids

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Increased rejection occurrence noticed with early withdrawal of steroidsAccording to a study published in an issue of Liver Transplantation, the official journal of the American Association for the Study of Liver Diseases (AASLD) and the International Liver Transplantation Society (ILTS), the early withdrawal of steroids after liver transplantation can lead to reduced tolerance to glucose and increased rejection occurrence.

This first double-blind placebo-controlled study was instrumental in emphasizing upon the effects of early withdrawal of steroids.

Saturday 24, Jul 2010

  Multiple doses of steroids helpful for preemies

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Multiple doses of steroids helpful for preemiesAdministration of a second dose of steroids to babies, still in the womb, can prove useful for reducing the risk of post-birth respiratory problems in the future without posing any concerns in terms of baby growth, according to a new research.

A 31 percent reduction was experienced in overall composite neonatal morbidity when a second steroid dose was administered to babies who are born before 34 weeks, as per study author Dr. James Kurtzman, an associate clinical professor in the division of maternal-fetal medicine in the department of obstetrics and gynecology at the University of California, Irvine.

The study demonstrates that we are faring better for prevention and management of premature births, as per Dr. Peter Bernstein, a maternal-fetal medicine specialist at Montefiore Medical Center in New York City.

Friday 02, Jul 2010

  Steroids not effective for treating traumatic brain injuries

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Steroids not effective for treating traumatic brain injuriesIndividuals suffering from traumatic brain injuries should not be administered with steroids with an aim to reduce the associated inflammation, according to a research.

It is estimated that approximately 1.4 million individuals in the United States alone suffer from Traumatic brain injuries every year causing 50,000 deaths.

This finding was disclosed by researchers after comparing mortality rates among patients who received steroids to those who received a placebo.

Monday 19, Apr 2010

  Inhaled steroids beneficial for patients with cystic fibrosis

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Inhaled steroids beneficial for patients with cystic fibrosisAccording to a finding presented in an issue of the American Journal of Respiratory and Critical Care Medicine and published by the American Thoracic Society, there is no difference in terms of benefits when comparisons are made between cystic fibrosis (CF) patients on inhaled corticosteroids and those who didn’t use inhaled steroids for six months.

Ian M. Balfour-Lynn, M.D., F.R.C.P., of the Department of Pediatric Respiratory Medicine at Royal Brompton Hospital in London, and six associates concluded that it is safe for the patients to stop using corticosteroids for lowering their drug burden, save money, and minimize adverse side effects.

Dr. Balfour-Lynn remarked that replacing the corticosteroids with a placebo was safe as it did not led to a significant increase in lung-related adverse effects leading to withdrawal from the study, nor an increased need for oral corticosteroids.

Thursday 01, Apr 2010

  Continued benefits possible only with regular administration of asthma drugs

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Continued benefits possible only with regular administration of asthma drugsAccording to new results from a comprehensive childhood asthma study, there are no improvements after the steroid drugs are discontinued for children whose asthma improved while taking these drugs for many years.

This study, published in advance online publication of the Journal of Pediatrics, disclosed that children who took the medications during the trial and now in their last teens displayed no differences in terms of asthma control when compared with the children who received the placebo.

Robert C. Strunk, M.D., a Washington University pediatrician at St. Louis Children’s Hospital and lead author of the study, said that asthma control gets in kids with asthma as they grow older.

Saturday 13, Mar 2010

  Phase III trial results of BENLYSTA presented

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Phase III trial results of BENLYSTA presentedHuman Genome Sciences, Inc. (Nasdaq: HGSI) and GlaxoSmithKline PLC (GSK) recently announced the full presentation of results from the first of two pivotal Phase 3 trials of BENLYSTAâ„¢ (belimumab) in seropositive patients with systemic lupus erythematosus (SLE), BLISS-52.

The data was presented in Philadelphia at the 73rd Annual Scientific Meeting of the American College of Rheumatology (ACR).

It was noted that belimumab plus standard of care in BLISS-52 attained a clinically significant improvement in patient response rate compared with placebo plus standard of care.

Friday 26, Feb 2010

  Frailty in older women possible of being treated with appetite-stimulating hormone

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Frailty in older women possible of being treated with appetite-stimulating hormoneGhrelin, a hormone that stimulates appetite, can be used as an effective option for offering relief to older women suffering from clinical frailty. This finding was revealed by a study presented by Penn Medicine researchers at ENDO, The Endocrine Society’s 91st Annual Meeting.

Frailty is a common geriatric syndrome that is characterized by unintentional weight loss, exhaustion, weakness, and low levels of anabolic hormones prompting increase in risk of falls, hospitalizations, disability, and even death.

Anne Cappola, MD, ScM, Assistant Professor of Medicine in Endocrinology, Diabetes, and Metabolism at the University of Pennsylvania School of Medicine, said that efforts to identify ways for preventing or treating common geriatric conditions has become highly important today due to the associated severe health consequences.

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