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Friday 30, Jul 2010

  Multiple steroid courses show efficacy for improving survival rate

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Multiple steroid courses show efficacy for improving survival rateAccording to a recently concluded study, multiple courses of steroids to expectant mothers could be more than just useful for improving the survival rate of preterm babies.

It was disclosed in the study that use of steroids by women in preterm labor can considerably reduce the need for preterm babies to be put on ventilation.

Babies need to be placed on ventilation when nursing mothers avoid steroid treatment, as per Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study.

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According to a recently concluded study, multiple courses of steroids to expectant mothers could be more than just useful for improving the survival rate of preterm babies.

It was disclosed in the study that use of steroids by women in preterm labor can considerably reduce the need for preterm babies to be put on ventilation.

From Bio-Medicine.org:

“The consensus in recent years has been to no longer give women in preterm labor more than one course of steroids because of possible adverse effects, but it means more babies are born needing ventilation,” said Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study. “These findings may give us back a tool to help give these fragile babies a better chance of survival.”

Before concerns arose in 2000 about safety of multiple courses of steroids, many mothers in on-and-off preterm labor received several rounds before delivering. Now, when mothers go into preterm labor, obstetricians will often administer only a single course of steroids to help strengthen the baby’s lungs upon birth. But if the birth is successfully held off for more than seven days, the mother does not receive another course of medication and the baby’s lungs may not be protected.

This is regrettable, because one of the biggest challenges for babies born preterm is breathing on their own. Many develop respiratory distress syndrome because their lungs have not developed a protective film over their air sacks, called surfactant, which aids in the transfer of oxygen and decreases the work of breathing. Because of that, they may receive medications and supplemental oxygen, which can cause problems of their own.

Babies need to be placed on ventilation when nursing mothers avoid steroid treatment, as per Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study.

Wednesday 07, Apr 2010

  Multiple courses of steroids can guard lungs of preterm babies

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Multiple courses of steroids can guard lungs of preterm babiesMultiple courses of steroids such as betamethasone can prove effective for enhancing the survival rate of babies to nursing women in preterm labor, as per a recent study. It was further revealed in the study that repeated courses of steroids do not bring a negative impact on brains of the babies as previously thought.

Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study, said that nursing mothers avoiding steroid treatment can experience babies needing ventilation.

Amin further remarked that there is still a need to conduct future studies before this treatment can be termed as completely safe and effective.

Wednesday 03, Mar 2010

  Multiple course steroid treatment protects lungs of preterm babies

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Multiple course steroid treatment protects lungs of preterm babiesSurvival rate and lung functioning of preterm babies can improve when repeated courses of steroids are administered to their nursing mothers during preterm labor, as per a study. The study also noted that the use of steroids does not lead to brain damage to baby in womb as was thought previously.

Babies need to be placed on ventilation when steroid-based treatment is avoided or delayed, according to Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study.

It was remarked by Amin that auditory brainstem evoked response or ABR can act as a window into children’s entire brain and there is no result that suggest that administration of multiple courses of betamethasone steroids do not lead to side effects on an infant’s brain.

Thursday 11, Feb 2010

  Safer preemie lung treatment options analyzed

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safer-preemie-lung-treatment-options-analyzedThe use of steroids for treating preemies between 28-32 weeks of age, does not lead to any harm. This finding was disclosed in an issue of Pediatrics and suggested that brains of babies remain virtually unaffected by steroid administration, a fact that nullifies the past belief that repeated courses of steroids in the womb lead to brain damage.

This finding is expected to offer crucial insights to members of the medical fraternity besides offering relief to expecting mothers.

Tuesday 19, Jan 2010

  Multiple steroid courses can protect lungs of preterm babies

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Multiple steroid courses can protect lungs of preterm babies

According to a latest study, repeated courses of steroids administered to nursing women during preterm labor have the potential to improve survival rate of babies. The study also suggested that there is no truth in the long-held belief that steroids cause brain damage to babies in the wombs.

Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study, remarked that babies go on ventilation in cases where steroid treatment is delayed or avoided by nursing mothers.

It was also remarked by Amin that ABR (auditory brainstem evoked response) can be termed as a window into the entire brain. The study concluded by suggesting that there were no results to suggest that an infant brain administered with multiple courses of betamethasone steroids gets affected in any way.

Saturday 24, Oct 2009

  Lungs of Preterm babies protected with multiple courses of steroids.

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Lungs of Preterm babies protected with multiple courses of steroids.Repeated courses of steroids administered to nursing women during preterm labor can prove effective when it comes to improving survival rate of babies. It was also suggested that steroids do not result in brain damage to baby in womb as was thought previously.

It was remarked by Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study, that more babies need ventilation when steroid treatment is delayed or avoided by nursing mothers.

Amin also remarked that ABR (auditory brainstem evoked response) can be termed as a window into the entire brain and there were no suggesting results for proving that an infant’s brain receiving multiple courses of betamethasone steroids gets affected in any way.

Saturday 03, Oct 2009

  Preemie lung treatment options prove safe

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Preemie lung treatment options prove safeAccording to findings of a study in an issue of Pediatrics, preemies between 28-32 weeks of age are not harmed by a treatment option that is no longer used to help in maturing lungs. The concerned study revealed that babies’ brains remain virtually unaffected; a fact that overrules the previously believed fact that repeated courses of steroids in the womb may lead to brain damage.

It is believed that this study would provide new insights to further clinic studies in the same regard.

Monday 28, Sep 2009

  Risk for respiratory infections enhanced by oxygen-rich lifesaving efforts

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Risk for respiratory infections enhanced by oxygen-rich lifesaving effortsEvery year, many thousands of premature infants fight a battle to breathe. Thanks to lifesaving interventions like steroids administered to mothers for stalling preterm labor, air enriched with extra oxygen, and even mechanical ventilation – most of these infants survive with enough lung function to grow and get discharged from the medical center.

However, a new research probing into one such intervention – air enriched with extra oxygen – revealed that breathing oxygen-enriched air in the early weeks can actually wrap signaling pathways, which can rev up the body for fighting against respiratory infections such as flu, according to University of Rochester Medical Center researcher Michael O’Reilly, Ph.D.

O’Reilly admits that there is more research to be undertaken in this aspect but he hopes that there is some way to enhance lung functioning in the first generation of survivors.

Wednesday 08, Jul 2009

  Repeated Courses Of Steroids – Safe On Preterm Babies

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Repeated Courses Of Steroids – Safe On Preterm BabiesA study finds that repeated courses of steroids to women in preterm labor do not result in brain damage of the baby in the womb as believed and that the treatment enhances the survival rate of the babies.

Previous studies showed neurological complications from multiple courses of dexamethasone, a steroid prepared with sulfur. However, clinicians do not use that steroid anymore and have switched to sulfur-free steroids, such as betamethasone. The study was based on infants who received betamethasone prior to birth, and they did not show the same adverse effects as previous studies.

Researchers said that there were no significant differences in the brain’s responses to the testing between the 50 babies who received one course of steroids and the 29 who received multiple courses, even when controlled for gestational age, birth weight, race and exposure to illegal drugs. There were also no significant differences between the 51 infants who received no steroids and those who did. The only medical difference between those infants who received one course and those who received more was that the ones who received more were less likely to need mechanical ventilation the day they were born.

Tuesday 16, Jun 2009

  Multiple Courses of Steroids protect lung of Preterm Babies

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Multiple Courses of Steroids protect lung of Preterm BabiesA recently concluded study revealed that repeated courses of steroids to nursing women in preterm labor can enhance the survival rate of babies. It was also revealed that multiple courses of steroids do not result in brain damage of the baby in womb as thought previously.

Sanjiv Amin, M.D., assistant professor of Pediatrics at the University of Rochester Medical center and author of the study, remarked that more babies are expected to be born needing ventilation when steroid treatment is avoided by the nursing mothers.

Amin also remarked that auditory brainstem evoked response (ABR) is like a window into the whole brain and there were no results that can prove that the brain of an infant whose mother received multiple courses of betamethasone steroids gets affected in any way.

It was also remarked by Amin that there is a need to conduct more relevant studies so that the treatment can be termed as completely safe and effective.

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