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Friday 23, Jul 2010

  Capsaicin useful for treating cancer of the prostate

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Capsaicin useful for treating cancer of the prostateCapsaicin, which is a pepper component used for turning up heat in jalapeqos, could be used for driving and killing cells of prostate cancer and not just for tongue burning, according to a study appearing in an issue of Cancer Research.

A team of researchers from the Samuel Oschin Comprehensive Cancer Institute at the Cedars-Sinai Medical Center in collaboration with colleagues from UCLA disclosed that the pepper ingredient could be useful to program death of cells or apoptosis of the prostate cancer cells.

Capsaicin prevents the molecular mechanism participating in pathways (NF-kappa Beta) leading to death of different cells and also prevents cancer cell progression through regulation of androgen receptors, which are steroid activated proteins controlling expression of certain growth related genes.

Wednesday 23, Jun 2010

  Capsaicin can provide relief to prostate cancer patients

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Capsaicin can provide relief to prostate cancer patientsCapsaicin, which is a pepper component used to turn up heat in jalapeqos and burn the tongue, can be helpful in driving and killing prostate cancer cells according to a study appearing in an issue of Cancer Research.

According to a team of researchers from the Samuel Oschin Comprehensive Cancer Institute at the Cedars-Sinai Medical Center in collaboration with colleagues from UCLA, the pepper component can be termed as useful for programming cell death or apoptosis of the prostate cancer cells.

Capsaicin prevents the molecular mechanism participating in pathways (NF-kappa Beta), which results in apoptosis of different cell types besides preventing cancer cell progression by regulating androgen receptors that are steroid activated proteins controlling expression of certain growth related genes.

Thursday 06, May 2010

  Prostate cancer progression can speed with hormonal nutritional supplements

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Prostate cancer progression can speed with hormonal nutritional supplementsAccording to a recent research, progression of prostate cancer and reduction in efficacy of anti-cancer drugs can be stimulated by hormonal components in over-the-counter dietary supplements.

This discovery by researchers at UT Southwestern Medical Center appeared in an issue of Clinical Cancer Research and reaffirmed that people visiting the doctors’ offices must inform them about any herbal or hormonal dietary supplements they are taking or considering taking.

It was recommended by the researchers that documentation of supplement use becomes part of routine health assessment for all patients, especially cancer patients.

Wednesday 10, Mar 2010

  Protein known to suppress androgen receptors may be useful for treating prostate cancer

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protein-known-to-suppress-androgen-receptors-may-be-useful-for-treating-prostate-cancerAccording to a finding reported in Proceedings of the National Academy of Sciences Online Early Edition, a protein known for regulating androgen receptor expression may be the focal point to stage and treat testosterone-fueled prostate cancer.

This finding was reported by researchers from the College of Georgia.

Dr. Yehia Daaka, Distinguished Chair in Oncologic Pathology in the MCG School of Medicine and co-author of the study, said that an increase in the number of androgen receptors is considered to be behind the progression of prostate cancer in men with advanced disease.

Collaborators on this study included Dr. Vijayabaskar Lakshmikanthan, postdoctoral fellow; Dr. Lin Zou, former postdoctoral fellow;  Jae Kim, graduate student; Dr. Nidia C. Messias, assistant professor; and Dr. Zhongzhen Nie, assistant professor; from the MCG Department of Pathology; and Drs. Allison Michal, and Jeffrey L. Benovic from Thomas Jefferson University.

Wednesday 17, Feb 2010

  Pepper component may prove effective for prostate cancer treatment

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Pepper component may prove effective for prostate cancer treatmentCapsaicin, a pepper component used in turning up heat in jalapeqos, can do more things than just burning up the tongue. In a study that appeared in an issue of Cancer Research, it was revealed that the pepper component can drive and kill prostate cancer cells to a considerable extent.

A team of researchers from the Samuel Oschin Comprehensive Cancer Institute at the Cedars-Sinai Medical Center in collaboration with colleagues from UCLA said that Capsaicin is useful when it comes to ensuring programmed cell death or apoptosis of the prostate cancer cells.

Capsaicin inhibits the activity of NF-kappa Beta, which is believed to be a molecular mechanism participating in pathways, resulting in apoptosis of different cell types. It also inhibits progression of cancer cells by regulating androgen receptors, which are steroid activated proteins controlling expression of specific growth related genes.

Thursday 28, Jan 2010

  Androgen receptor suppressing protein can improve diagnosis and treatment of prostate cancer

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prostate_cancerAccording to researchers from the Medical College of Georgia, a protein that is helpful in regulating expression of androgen receptors may prove to be a new focal point for staging and treating testosterone-fueled prostate cancer.

It was noted that levels of the protein, βarrestin2, were lower in certain prostate cancer cells than in normal prostate cells. It was also noted that the expression of testosterone-fed androgen receptors is higher in such cases.

The findings were reported in Proceedings of the National Academy of Sciences Online Early Edition.

The study’s corresponding author, Dr. Yehia Daaka, Distinguished Chair in Oncologic Pathology in the MCG School of Medicine, said that an increase in the volume of androgen receptors is considered to be behind prostate cancer progression in men with advanced complication.

Wednesday 13, Jan 2010

  Prostate cancer cells can be killed by Capsaicin

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Prostate cancer progression can be triggered by hormonal nutritional supplementsAccording to a study published in an issue of Cancer Research, a popular pepper component used to turn up heat in jalapeqos is effective for driving and killing prostate cancer cells along with burning the tongue.

Capsaicin, the pepper component, is effective for facilitating prostate cancer cells to undergo programmed cell death or apoptosis, as per a team of researchers from the Samuel Oschin Comprehensive Cancer Institute at the Cedars-Sinai Medical Center in collaboration with colleagues from UCLA.

Capsaicin proves its worth by curbing cancer cell growth by regulating androgen receptors, which are steroid activated proteins controlling expression of certain growth relating genes. Since it inhibits the NF-kappa Beta, which is regarded as a molecular mechanism participating in pathways leading to apoptosis in varying cell types, it is able to deliver such results.

Monday 21, Dec 2009

  Progression of prostate cancer may speed up with hormonal nutritional supplements

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Progression of prostate cancer may speed up with hormonal nutritional supplementsResearchers at UT Southwestern Medical Center have discovered that progression of prostate cancer may be promoted and a reduction in the effectiveness of anti-cancer drugs may be experienced with the presence of hormonal components in over-the-counter dietary supplements.

The findings, which appear in today’s issue of Clinical Cancer Research, reaffirm that patients must communicate their doctors about their present or expected use of herbal or hormonal dietary supplements before seeking an advice.

Dr. Roehrborn, Dr. Shahrokh Shariat, a resident in urology and the study’s lead author, and their colleagues analyzed the supplement and found that product label listed ingredients were either not present or misrepresented about concentrations of the present ingredients and even failed to list all the containing steroid hormones in the product.

Tuesday 15, Dec 2009

  Androgen suppressing receptors can enhance diagnosis of prostate cancer

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Androgen suppressing receptors can enhance diagnosis of prostate cancer  According to medical College of Georgia researchers, βarrestin2, a protein that is useful for regulating expression of androgen receptors can prove a new focal point for staging and curing testosterone-fueled prostate cancer. The findings of this study were reported in Proceedings of the National Academy of Sciences Online Early Edition.

An increase in the number of androgen receptors is what is considered behind the growth of prostate cancer progression in men with advanced disease, as per study’s corresponding author, Dr. Yehia Daaka, Distinguished Chair in Oncologic Pathology in the MCG School of Medicine.

The involved collaborators included Dr. Vijayabaskar Lakshmikanthan, postdoctoral fellow; Dr. Lin Zou, former postdoctoral fellow;  Jae Kim, graduate student; Dr. Nidia C. Messias, assistant professor; and Dr. Zhongzhen Nie, assistant professor; from the MCG Department of Pathology; and Drs. Allison Michal and Jeffrey L. Benovic from Thomas Jefferson University.

Friday 04, Sep 2009

  Capsaicin found efficacious for driving and killing prostate cancer cells

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Capsaicin found efficacious for driving and killing prostate cancer cellsCapsaicin, which is popularly known to the world as the pepper component used in turning up heat in jalapeqos, is not only meant for burning the tongue but also for driving and killing prostate cancer cells according to a study published in an issue of Cancer Research.

According to a team of researchers from the Samuel Oschin Comprehensive Cancer Institute at the Cedars-Sinai Medical Center in collaboration with colleagues from UCLA, Capsaicin can prove to be beneficial for resulting in prostate cancer cells to undergo programmed cell death or apoptosis.

Since Capsaicin facilitates the inhibition of the activity of NF-kappa Beta that is considered to be a molecular mechanism participating in pathways leading to apoptosis in varying cell types, it proves effective inhibiting growth of cancer cells by regulating androgen receptors, which are steroid activated proteins controlling expression of certain growth relating genes.

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