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Tuesday 06, Jan 2015

  Gold Coast Suns And Carlton In AFL Doping Saga

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Gold Coast Suns And Carlton In AFL Doping Saga

The AFL doping scandal has expanded its horizons than previously thought and revealed, with the Australian Sports Anti-Doping Authority accusing Essendon players of using a second banned drug and sports scientist Stephen Dank of trafficking peptides to Gold Coast Suns and Carlton club officials and covering up doping by a footballer from Gold Coast.

An outline of the case of ASADA and other documents presently before a specially-convened AFL Tribunal alleged that Stephen Dank supplied banned drugs including Human growth hormone (HGH) to a Carlton coach and the banned peptide CJC-1295 to more than one official at the Gold Coast Suns. The sports scientist is also accused of covering up the use of CJC-1295 BY Gold Coast defender Nathan Bock, who retired from the AFL earlier this year.

 The new drug and the involvement of other clubs were revealed by ASADA’s senior counsel, Malcolm Holmes QC, in an outline of the case and a charge sheet issued against Dank. The charges involving Carlton pertain to a high-profile coach no longer working at the club. It is alleged by the Australian Sports Anti-Doping Authority that Stephen Dank provided one or more of Human growth hormone, SARMs, Hexarelin, Mechano Growth Factor, and CJC-1295 to the coach between March and October 2012. The charges involving the Suns predate the Essendon supplements scandal. ASADA also alleges that Dank administered Bombers players with Hexarelin — as well as TB4 — during his time at the club.

The AFL Tribunal hearings into the Essendon supplements scandal will resume from January 12 after a break for Christmas. In a statement, Tribunal chairman David Jones said the hearing of the proceedings was confirmed to commence on December 15, 2014, to continue for a number of days prior to Christmas and then resume on January 12, 2015.

The AFL Anti-Doping Tribunal is chaired by former county court judge Jones, another former county court judge John Nixon and barrister, and former Swans player Wayne Henwood.

According to media reports, the Australian Sports Anti-Doping Authority will seek assistance of the Supreme Court in an attempt to force Shane Charter and compound pharmacist Nima Alavi to give evidence to the Tribunal.

In December, Charter had remarked that he has been bashed and received death threats. Charter – the biochemist who sourced the banned peptide Thymosin beta-4 for Dank, further urged authorities to subpoena Stephen Dank. Essendon has maintained that its players were given Thymomodulin, a Thymosin peptide permitted for use in sport, and not Thymosin Beta 4 throughout 2012. The case of ASADA is heavily reliant on a sworn statement and other documents provided by Charter who has provided details of his role in importing an order of peptides, including Thymosin Beta 4, in December 2011, from China.

Charter is the star witness of ASADA and alleged supplied the substances to sports scientist Stephen Dank. Since the Tribunal does not have the powers to demand that Alavi and Charter appear, the legal team of ASADA is likely to approach the Supreme Court seeking subpoenas under the Commercial Arbitration Act.

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Thursday 12, Jun 2014

  Athletes Abuse Non-Approved Therapeutic Compounds For Performance Gains

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Athletes Abuse Non-Approved Therapeutic Compounds For Performance Gains

Non-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) are commonly being sold on the black market because of their performance enhancing qualities. This finding was revealed by researchers from the German Sport University Cologne in Germany in a study appearing in an issue of Drug Testing and Analysis published by Wiley-Blackwell.

In a product sold via the internet, the availability of authentic Selective Androgen Receptor Modulators was demonstrated for the first time by the detection of the drug candidate Andarine. SARMs represent a class of therapeutics that are used for treating health conditions like osteoporosis, benign prostatic hyperplasia (BPH), sarcopenia, and cancer cachexia. However, none of the agents are approved for therapeutic use though SARMs are gaining widespread popularity in the sport doping communities as it is believed that they offer the advantages of traditional anabolic androgenic steroids like Testosterone with fewer unwanted side effects.

The World Anti-Doping Agency (WADA) prohibited the use of SARMs in sports in 2008 because of their potential for misuse. The World Anti-Doping Agency is in constant touch with drug evaluation bodies, medicine agencies, and pharmaceutical and biotechnological companies on the issues of therapeutics being misused in sports. The preventive approach of WADA was validated with the finding of non-approved arylpropionamide-derived SARM termed Andarine that was commercially available. Declared as green tea extracts and face moisturizer to pass customs, this product was available on the internet for a low price.

Mario Thevis, Ph.D., and colleagues, analyzed the advertised product using state-of-the-art mass spectrometric approaches with high resolution/high accuracy (tandem) mass spectrometry for proving that SARMs lacking clinical approval are distributed and potentially misused in sports. Dr. Thevis said one unit (30 mL) was purchased online and delivered in a box labeled to contain face moisturizer and green tea extract and the sealed bottle did not declare any content and no further documents accompanied package.

Dr. Thevis explained that LC-MS (/MS) analysis of this solution disclosed the presence of S-4 at approximately 150 mg/mL with equal amounts in each container, yielding a total of 4.5 g of the Selective Androgen Receptor Modulator. The active ingredient was identified and characterized by comparison to synthesized reference material regarding retention time and production mass spectrum, its elemental composition (via high resolution/high accuracy mass spectrometry), and elucidation of its mass spectrometric behavior. It was also noted that a considerable amount of byproduct was observed besides the detection of the active ingredient S-4. Dr. Thevis said major concerns result from these findings and added that this product with considerable anabolic properties is readily available without sufficient research on its undesirable effects and this is especially significant where uncontrolled dosing is applied and drug impurities with unknown effects are present in considerable amounts as observed in the studied material. Dr. Thevis concluded our study demonstrates once more that the misuse of therapeutics without clinical approval by athletes cannot be dismissed.

The issue was addressed at the Conference of Parties to the International Convention against Doping in Sport, at the United Nations Educational, Scientific and Cultural Organization’s (UNESCO) headquarters in Paris.

pdf_iconDownload in PDF: Athletes Abuse Non-Approved Therapeutic Compounds For Performance Gains

Friday 20, Apr 2012

  SARMS sweeping world sport

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SARMS or Selective Androgen Receptor Modulators that mimic testosterone and totally undetectable are sweeping world sport these days.

The new designer drug is believed to be already being used in Australian high performance sport.

SARMS just enhances testosterone production and/or utilisation,” Charlie Francis, former coach of Ben Johnson, said.”And you throw that together with human growth hormone and you’ve got a pretty potent cocktail.”

Thursday 19, Apr 2012

  Hi-tech drugs may remain totally undetectable

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A new designer drug that is already being used in Australian high-performance sport is sweeping world sport.

The drug mimics testosterone and is totally undetectable. Selective Androgen Receptor Modulators (SARMS) have widely become popular on internet forums and received thousands of testimonials.

“We think those numbers are more in the double digits. Now that’s a concern. If there is more than 10 per cent of the athletes in the world being tempted to take the shortcut by taking prohibited substances, then we’ve got an issue that is not being confronted as well as it should be,” WADA said.

Tuesday 30, Nov 2010

  Potential pharmaceutical agents sold as doping products

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Potential pharmaceutical agents sold as doping productsResearchers from the German Sport University Cologne in Germany have disclosed that non-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) are prompting a demand high due to their performance enhancement qualities.

The study highlights that the misuse of therapeutics by athletes, without clinical approval, cannot be dismissed, as per Mario Thevis, Ph.D.

Selective Androgen Receptor Modulators (SARMs) represents a class of therapeutics meant to treat health complications such as benign prostatic hyperplasia (BPH), sarcopenia, osteoporosis, and cancer cachexia. They are gaining popularity in the world of professional sport doping community because they offer advantages of traditional anabolic/androgenic steroids such as testosterone with fewer unwanted side effects.

Tuesday 07, Sep 2010

  Promising pharmaceutical agents proving as doping products

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Promising pharmaceutical agents proving as doping productsPerformance enhancing qualities of non-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) are prompting a demand high, according to researchers from the German Sport University Cologne in Germany.

SARMs represent a promising class of therapeutics for treating diseases such as benign prostatic hyperplasia (BPH), sarcopenia, osteoporosis, and cancer cachexia and gaining popularity in the sports doping community as they provide benefits of traditional anabolic/androgenic steroids such as testosterone with fewer unwanted side effects.

Mario Thevis, Ph.D. remarked that the study demonstrates that the misuse of therapeutics by athletes, without clinical approval, cannot be dismissed.

Wednesday 26, May 2010

  SARMs emerging as doping products in sports

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SARMs emerging as doping products in sportsNon-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) are being sold for their performance enhancing qualities on the black market, as per researchers from the German Sport University Cologne in Germany.

This availability of authentic SARMs was recently highlighted after detecting Anadrine in a product sold on the Internet and is getting popular as SARMs provide advantages of traditional anabolic/androgenic steroids such as testosterone with fewer unwanted side effects.

Mario Thevis, Ph.D., said that the study highlighted that the misuse of therapeutics without clinical approval cannot be overruled.

Monday 01, Mar 2010

  SARMs sale witnessing highs like never before

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SARMs sale witnessing highs like never beforeThere have many highs in the sale of non-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) in the black market for their performance enhancing qualities.

This finding was revealed by researchers from the German Sport University Cologne in Germany when the detection of the drug candidate Andarine was demonstrated in a product sold via the Internet.

The issue of SARMs sold openly and cheaply (readily available without sufficient research on its undesirable effects) in the black market was recently addressed at the Conference of Parties to the International Convention against Doping in Sport, held October 26-28, 2009 at the United Nations Educational, Scientific and Cultural Organization’s (UNESCO) headquarters in Paris.

Wednesday 10, Feb 2010

  SARM sale on high for enhancing performance

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sarm-sale-on-high-for-enhancing-performanceThe sale of non-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) is on an all-time high in the Internet black market. According to researchers from the German Sport University Cologne in Germany, this demand hike is due to the performance enhancing features of these SARMs.

The researchers were able to identify one drug that was sold on the Internet that included Andarine suggesting that anabolic agents are readily and affordably sold on the online black market.

The study findings were presented in an issue of Drug Testing and Analysis published by Wiley-Blackwell.

John Fahey, WADA President, said that strict laws need to be adopted by government agencies for preventing distribution and sale of steroids in sporting events.

Thursday 17, Dec 2009

  New sports doping products sold on the Black Market

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New sports doping products sold on the Black MarketNon-steroidal and tissue-selective anabolic agents such as Selective Androgen Receptor Modulators (SARMs) are being openly sold on the black market because of their performance enhancing characteristics, according to researchers from the German Sport University Cologne in Germany.

This finding emerged after detection of the drug candidate Andarine in a product sold via the Internet that highlighted that the availability of authentic SARMs.

Mario Thevis, Ph.D., and colleagues, said that SARMs that come with considerable anabolic properties are readily available without sufficient research on their undesirable effects. This issue was recently addressed at the Conference of Parties to the International Convention against Doping in Sport, held October 26-28, 2009 at the United Nations Educational, Scientific and Cultural Organization’s (UNESCO) headquarters in Paris.

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