A shared process of decision making can be beneficial in assisting doctors and parents who face the extraordinarily complex and controversial choice when infants are born with born with genetic or anatomical anomalies in sexual development and selected for elective corrective surgery.

“Difficult Decisions: Disorders of Sex Development and Surgical Intervention” is published online in the August issue of the Journal of Pediatric Endocrinology and Metabolism.

The big issue to be addressed is the absence of standard approach for infants born with sex development disorder (SDD) or with atypical sexual development.

Tags: congenital adrenal hyperplasia, sex development disorder, sex steroids

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A new research paper has suggested that a shared process of decision making could assist parents and doctors who face the extraordinarily complex and controversial choice when infants are born with born with genetic or anatomical anomalies in sexual development and considered for elective corrective surgery.

Alexander Kon, senior author of the study and associate professor of pediatrics and bioethics at the UC Davis School of Medicine, said the big issue that is addressed is that there is lack of standard approach for infants born with sex development disorder (SDD) or with atypical sexual development.

“Difficult Decisions: Disorders of Sex Development and Surgical Intervention” is published online in the August issue of the Journal of Pediatric Endocrinology and Metabolism.

Tags: congenital adrenal hyperplasia, sex development disorder, sex steroids

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According to new bench research from the Mayo Clinic, female sex hormones could work with beta-agonists in minimizing airway constriction.

Lead student researcher, Elizabeth A. Townsend, of the Mayo Clinic Department of Physiology and Biomedical Engineering, said that it will be of interest to ascertain whether sex steroids such as estrogen and progesterone play a role in modulation of airway tone.

The findings are being presented at the ATS 2010 International Conference in New Orleans.

Tags: Estrogen, estrogens, progesterone, sex steroids, steroids

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Researchers from the Medical College of Georgia have been able to discover chromodomain helicase DNA binding protein 7 or CHD7, a gene, which is responsible for many of the puberty-related complications.

The research team discovered that the gene is able to get mutated in a multi-system complication characterized by complications such as mental retardation and loss of hearing, which is known as the CHARGE syndrome.

The syndrome has an impairment effect on the sense of smell and can prevent production of hormones and sex steroids.

Tags: puberty, sex steroids, steroids

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A gene, chromodomain helicase DNA binding protein 7 or CHD7, has been discovered by researchers from the Medical College of Georgia. This gene is responsible for many of the known complications related with puberty.

It was found by the researchers that this gene gets mutated in CHARGE syndrome, which is a multi-system complication characterized by complications such as mental retardation and loss of hearing; the two disorders are idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome.

The CHARGE syndrome was found to have an impairment effect on the smell sense and inhibits sex steroids and hormone production.

Tags: CHARGE syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome, puberty disorders, sex steroids, steroids

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Overweight children and adults have low levels of SHGB, a protein, in their blood. This protein transports sex steroids besides regulating their entry into tissues.

Geoffrey Hammond and colleagues at the University of British Columbia, Vancouver, recently provided an explanation as to why low levels of SHGB are such a good marker of the metabolic syndrome.

This study is expected to offer implications to aid medical practitioners all over the world for understand medical disorders that increase an individual’s risk of developing type 2 diabetes and heart disease in a better manner.

Tags: sex steroids, SHGB, steroids, type 2 diabetes

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According to a new bench research from the Mayo Clinic, female sex hormones can work with beta-agonists to reduce airway constriction.

The findings are being presented at the ATS 2010 International Conference in New Orleans.

Lead student researcher, Elizabeth A. Townsend, of the Mayo Clinic Department of Physiology and Biomedical Engineering, where she is completing her Ph.D., said sex steroids may play a role in airway tone modulation.

Tags: Asthma, sex steroids, steroids

Posted in Steroid Cycles, steroid nation, Steroids and Anabolic Steroids

A gene that is believed to be responsible for many of the known puberty complications has been identified by researchers from the Medical College of Georgia. The gene is known as chromodomain helicase DNA binding protein 7, or CHD7.

The researchers found that the gene gets mutated in CHARGE syndrome that is a multi-system complication characterized by many problems such as hearing loss and mental retardation; the two disorders are idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome.

It was noted that the CHARGE syndrome may have an impairment effect on the sense of smell along with inhibition of sex steroid and hormone production.

Tags: CHARGE syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome, puberty disorders, sex steroids, steroids

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There is a possible link between irritability and perimenopausal and postmenopausal women but there are not any study results or evidence suggesting an association.

A study examining association between menopause with sex steroids, gonadotrophins, prolactin and thyroid hormones and with samples including of 163 women, with a mean age of 55.1 years (SD = 5.7) in relation to 124 postmenopausal and 26 perimenopausal women, suggested that a high score is visible on inward and outward irritability scales in women with chronic disease.

Though not linked directly with menopause, it could have been partially influenced by the growing age of menopausal women.

The results of this study are seen by many as evidence that suggests a possible link between menopause and outward irritability.

Tags: chronic disease, gonadotrophins, menopause, sex steroids

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Monash University scientists have been able to rejuvenate the immune systems of mice and humans using a common hormone.

The scientists were led by Associate Professor Richard Boyd and Dr Jayne Sutherland from the Monash Immunology and Stem Cell Laboratories. The involved scientists revitalized the thymus, which is responsible for producing the T cells needed for fighting infection but which shuts down from early childhood age.

The achievement was published in an issue of the Journal of Immunology and is expected to offer a new hope to patients with cancer, AIDS and other immunodeficiencies and for transplant patients.

Tags: sex steroids, steroids, thymus

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